Aclaris Therapeutics, Inc.
Business
Aclaris Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing novel small and large molecule product candidates for immuno-inflammatory diseases. It develops monoclonal and bispecific biologics and oral small-molecule kinase inhibitors, including bosakitug, ATI-052, ATI-2138, lepzacitinib and zunsemetinib, and provides contract research services. Key business areas include biologics development, small-molecule discovery and preclinical programs supported by its proprietary KINect platform, and partnered development/licensing activities. It advances candidates through clinical trials and pursues collaborations and commercialization partnerships across the United States, Greater China (via licensees) and other international markets.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 8 | 19 | 31 | 30 | 7 | |
| Cost of revenue | 2 | 3 | 3 | 4 | 5 | |
| Research and development | 53 | 34 | 98 | 78 | 44 | |
| General and administrative | 22 | 22 | 32 | 25 | 24 | |
| Licensing | 5 | 13 | 15 | 8 | — | |
| Revaluation of contingent consideration | 2 | 3 | −27 | 5 | 24 | |
| In-process research and development | — | 87 | 7 | — | — | |
| Total costs and expenses | 84 | 161 | 129 | 120 | 96 | |
| Loss from operations | −76 | −142 | −97 | −90 | −90 | |
| Interest income | 8 | 8 | 9 | — | — | |
| Non-cash royalty income | 4 | 2 | — | — | — | |
| Total other income | 11 | 10 | 9 | — | — | |
| Net loss | −65 | −132 | −88 | −87 | −91 | |
| Net loss per share, basic | −0.53 | −1.71 | −1.27 | −1.33 | −1.6 | |
| Net loss per share, diluted | −0.53 | −1.71 | −1.27 | −1.33 | −1.6 | |
| Weighted average common shares outstanding, basic | 123 | 77 | 70 | 65 | 57 | |
| Weighted average common shares outstanding, diluted | 123 | 77 | 70 | 65 | 57 | |
| Unrealized gain on marketable securities, net of tax of $0 | 513,000 | 203,000 | 791,000 | −673,000 | −229,000 | |
| Total other comprehensive income | 513,000 | 203,000 | 791,000 | −673,000 | −130,000 | |
| Comprehensive loss | −64 | −132 | −88 | −88 | −91 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 20 | 25 | 40 | 45 | 27 | |
| Short-term marketable securities | 71 | 89 | 79 | 172 | 164 | |
| Accounts receivable, prepaid expenses and other current assets | 6 | 12 | — | — | — | |
| Total current assets | 96 | 126 | 129 | 232 | 205 | |
| Marketable securities | 61 | 90 | 63 | 12 | 34 | |
| Property and equipment, net | 761,000 | 1 | 2 | 1 | 1 | |
| Other assets | 3 | 3 | 4 | 3 | 4 | |
| Total assets | 160 | 220 | 197 | 255 | 251 | |
| Accounts payable | 13 | 5 | 9 | 10 | 10 | |
| Accrued expenses | 9 | 20 | 19 | 9 | 10 | |
| Deferred income | 4 | 4 | — | — | — | |
| Other current liabilities | 3 | 3 | 3 | — | 693,000 | |
| Total current liabilities | 29 | 32 | 31 | 22 | 23 | |
| Other liabilities | 2 | 4 | 3 | 2 | 2 | |
| Deferred income, net of current portion | 16 | 20 | — | — | — | |
| Contingent consideration | 11 | 9 | 6 | 33 | 28 | |
| Total liabilities | 57 | 65 | 40 | 57 | 54 | |
| Preferred stock, $0.00001 par value; 10,000,000 shares authorized and no shares issued or outstanding at December 31, 2025 and December 31, 2024 | — | — | — | — | — | |
| Common stock, $0.00001 par value; 400,000,000 and 200,000,000 shares authorized at December 31, 2025 and December 31, 2024, respectively; 120,499,433 and 107,850,124 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | |
| Additional paidin capital | 1,070 | 1,058 | 928 | 881 | 793 | |
| Accumulated other comprehensive income | 610,000 | 97,000 | −106,000 | −897,000 | −224,000 | |
| Accumulated deficit | −968 | −903 | −771 | −682 | −595 | |
| Total stockholders' equity | 103 | 156 | 157 | 198 | 197 | |
| Total liabilities and stockholders' equity | 160 | 220 | 197 | 255 | 251 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −65 | −132 | −88 | −87 | −91 | |
| Depreciation and amortization | 454,000 | 807,000 | 863,000 | 797,000 | 923,000 | |
| Stock-based compensation expense | 12 | 11 | 21 | 15 | 14 | |
| Accounts receivable, prepaid expenses and other assets | 6 | −5 | — | — | — | |
| Accounts payable | 8 | −4 | −1 | 368,000 | 4 | |
| Accrued expenses and other liabilities | −8 | −4 | 12 | — | — | |
| Deferred income | −4 | 24 | — | — | — | |
| Net cash used in operating activities | −47 | −20 | −78 | −68 | −52 | |
| Purchases of property and equipment | −111,000 | −121,000 | −1 | −605,000 | −308,000 | |
| Purchases of marketable securities | −40 | −120 | −136 | −165 | −235 | |
| Proceeds from sales and maturities of marketable securities | 89 | 86 | 183 | 178 | 68 | |
| Payments of deferred transaction consideration for in-licensed assets | −833,000 | — | — | — | — | |
| Acquisition of in-licensed assets, including transaction costs | — | −36 | — | — | — | |
| Net cash provided by (used in) investing activities | 48 | −70 | 46 | 13 | −168 | |
| Proceeds from issuance of common stock under securities purchase agreement, net of issuance costs | — | 75 | 27 | 73 | — | |
| Payments of deferred transaction consideration for in-licensed assets | −5 | — | — | — | — | |
| Payments of employee withholding taxes related to restricted stock unit award vesting | −446,000 | −409,000 | −102,000 | −34,000 | −3 | |
| Proceeds from exercise of employee stock options and the issuance of stock | — | 32,000 | 94,000 | 157,000 | 1 | |
| Net cash (used in) provided by financing activities | −6 | 75 | 27 | 73 | 225 | |
| Net decrease in cash and cash equivalents | −5 | −15 | −5 | 18 | 5 | |
| Additions to property and equipment included in accounts payable | 21,000 | — | — | 24,000 | 143,000 | |
| Fair value of warrants issued in connection with in-license agreement | — | 45 | — | — | — | |
| Deferred transaction consideration in connection with in-license agreement | — | 6 | — | — | — |