Acrivon Therapeutics, Inc.
Business
Acrivon Therapeutics is a clinical-stage biopharmaceutical company discovering and developing precision oncology medicines using its proprietary Generative Phosphoproteomics AP3 platform to identify drug-sensitive tumors and predict patient responders based on proteomic biomarkers. The company's lead program, ACR-368 (a CHK1/2 inhibitor licensed from Eli Lilly), is in Phase 2b development for endometrial cancer with a companion diagnostic called OncoSignature. Internally discovered programs include ACR-2316 (a WEE1/PKMYT1 dual inhibitor in Phase 1) and ACR-6840 (a CDK11 inhibitor in preclinical development). Acrivon operates clinical trials in the United States and Europe with an internal CLIA-certified laboratory for OncoSignature testing.
Summary from 10-K filed 2026-03-19
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 60 | 64 | 46 | 24 | — | |
| General and administrative | 24 | 25 | 21 | 9 | — | |
| Total operating expenses | 84 | 89 | 67 | 33 | 16 | |
| Loss from operations | −84 | −89 | −67 | −33 | −16 | |
| Interest income | 6 | 9 | 7 | — | — | |
| Other expense, net | −270,000 | −558,000 | −322,000 | 2 | 21,000 | |
| Total other income, net | 6 | 9 | 7 | 1 | −59,000 | |
| Net loss | −78 | −81 | −60 | −31 | −16 | |
| Net loss per sharebasic | −2.02 | −2.38 | −2.74 | −7.56 | −9.32 | |
| Net loss per sharediluted | −2.02 | −2.38 | −2.74 | −7.56 | −9.32 | |
| Weighted-average common stock outstandingbasic | 39 | 34 | 22 | 4 | 2 | |
| Weighted-average common stock outstandingdiluted | 39 | 34 | 22 | 4 | 2 | |
| Unrealized (loss) gain on available-for-sale investments, net of tax | −336,000 | 530,000 | 12,000 | −95,000 | — | |
| Comprehensive loss | −78 | −80 | −60 | −31 | — |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 41 | 40 | 36 | 30 | 100 | |
| Short-term investments | 77 | 140 | 91 | 98 | — | |
| Prepaid expenses and other current assets | 2 | 2 | 2 | 4 | 805,000 | |
| Total current assets | 120 | 182 | 130 | 132 | 100 | |
| Property and equipment, net | 5 | 4 | 3 | 2 | 290,000 | |
| Operating lease right-of-use assets | 3 | 4 | 4 | 5 | 6 | |
| Long-term investments | — | 5 | — | 42 | — | |
| Restricted cash | 203,000 | 198,000 | 414,000 | 388,000 | 388,000 | |
| Other assets | 2 | 2 | 251,000 | — | — | |
| Total assets | 130 | 197 | 138 | 181 | 107 | |
| Accounts payable | 2 | 758,000 | 5 | 904,000 | 964,000 | |
| Accrued expenses and other current liabilities | 12 | 15 | 7 | 5 | 1 | |
| Operating lease liabilities, current | 1 | 1 | 877,000 | 726,000 | 664,000 | |
| Total current liabilities | 16 | 17 | 13 | 7 | 3 | |
| Operating lease liabilities, non-current | 2 | 3 | 4 | 4 | 5 | |
| Total liabilities | 17 | 20 | 17 | 11 | 8 | |
| Commitments and contingencies (Note 13) | — | — | — | — | — | |
| Common stock, $0.001 par value; 500,000,000 shares authorized as of December 31, 2025 and 2024; 31,648,856 and 31,231,264 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 31,000 | 31,000 | 23,000 | 22,000 | 2,000 | |
| Additional paid-in capital | 387 | 373 | 238 | 227 | 1 | |
| Accumulated other comprehensive income | 111,000 | 447,000 | −83,000 | −95,000 | — | |
| Accumulated deficit | −275 | −197 | −116 | −56 | −25 | |
| Total stockholders' equity | 113 | 177 | 121 | 170 | −24 | |
| Total liabilities and stockholders' equity | 130 | 197 | 138 | 181 | 107 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −78 | −81 | −60 | −31 | −16 | |
| Depreciation expense | 1 | 1 | 500,000 | 400,000 | 37,000 | |
| Stock-based compensation expense | 15 | 14 | 12 | 2 | 497,000 | |
| Non-cash operating lease expense | 1 | 932,000 | 778,000 | — | — | |
| Net amortization of premiums and accretion of discounts on investments | −437,000 | −4 | −3 | −698,000 | — | |
| Prepaid expenses and other current assets | 190,000 | 237,000 | 2 | −4 | −764,000 | |
| Accounts payable | 2 | −4 | 4 | −245,000 | 798,000 | |
| Accrued expenses and other liabilities | −3 | 8 | 3 | 3 | 866,000 | |
| Operating lease liabilities | −936,000 | −1 | −754,000 | −667,000 | −572,000 | |
| Other assets | 137,000 | −1 | — | — | — | |
| Net cash used in operating activities | −64 | −66 | −43 | −30 | −14 | |
| Purchases of investments | −82 | −203 | −57 | −150 | — | |
| Proceeds from maturities of investments | 150 | 154 | 109 | 11 | — | |
| Purchases of property and equipment | −2 | −3 | −1 | −2 | −238,000 | |
| Net cash provided by (used in) investing activities | 66 | −52 | 51 | −142 | −238,000 | |
| Proceeds from issuance of common stock in private placement | — | 70 | — | 5 | — | |
| Proceeds from issuance of pre-funded warrants in private placement | — | 60 | — | — | — | |
| Proceeds from exercise of stock options | 1,000 | 90,000 | 775,000 | 24,000 | 1,000 | |
| Payments of offering costs | — | −7 | −1 | −3 | — | |
| Payments of tax withholdings related to vesting of restricted stock units | −750,000 | −3 | −1 | — | — | |
| Net cash (used in) provided by financing activities | −749,000 | 121 | −2 | 102 | 112 | |
| Net increase in cash, cash equivalents, and restricted cash | 2 | 4 | 7 | −70 | 98 | |
| Deferred offering costs in accrued expenses and other current liabilities | 143,000 | — | — | — | — | |
| Purchases of property and equipment included in accounts payable | — | 17,000 | 635,000 | — | 30,000 | |
| Right-of-use assets obtained in exchange for operating lease liability | — | 56,000 | 437,000 | — | 6 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Acrivon Therapeutics, Inc.'s CIK number?
Acrivon Therapeutics, Inc.'s SEC CIK number is 0001781174 (1781174). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Acrivon Therapeutics, Inc.'s SEC filings?
All of Acrivon Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Acrivon Therapeutics, Inc. last report earnings?
Acrivon Therapeutics, Inc. (ACRV) most recently filed an earnings 8-K with the SEC on May 13, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-221626). This is Acrivon Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Acrivon Therapeutics, Inc.'s most recent earnings 8-K?
Acrivon Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 13, 2026 under accession 0001193125-26-221626. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Acrivon Therapeutics, Inc.'s latest earnings 8-K →
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