Allogene Therapeutics, Inc.
Business
Allogene Therapeutics, Inc. is a clinical-stage immuno-oncology company developing genetically engineered allogeneic CAR T cell therapies for cancer and autoimmune diseases. Its main product candidates and development activities include cemacabtagene ansegedleucel (cema-cel), ALLO-316, ALLO-329, the anti-CD52 agent ALLO-647, and associated gene‑editing, CAR constructs and manufacturing services. The company organizes operations across oncology programs (e.g., LBCL and RCC), autoimmune disease programs, and a manufacturing/technical operations platform (Cell Forge 1) supporting clinical and potential commercial production. It pursues global clinical development and commercialization through clinical trial sites, strategic collaborations, licensed rights in the U.S., EU and UK, and an off‑the‑shelf frozen product distribution model.
Summary from filing dated 2025-03-13
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Collaboration revenue - related party | 0 | 22,000 | 95,000 | 156,000 | 114 | |
| Research and development | 150 | 192 | 243 | 256 | 220 | |
| General and administrative | 57 | 65 | 72 | 79 | 74 | |
| Impairment of long-lived asset | 2 | 16 | 13 | 0 | 0 | |
| Total operating expenses | 209 | 273 | 328 | 336 | 294 | |
| Loss from operations | −209 | −273 | −328 | −336 | −180 | |
| Interest and other income, net | 19 | 20 | 18 | 5 | 2 | |
| Interest expense | −1 | −181,000 | 0 | — | — | |
| Other income (expense), net | 215,000 | −4 | −18 | −9 | −4 | |
| Total other income (expense), net | 18 | 16 | 472,000 | −5 | −2 | |
| Loss before income taxes | −191 | −257 | −327 | — | −257 | |
| Income tax expense | 0 | −443,000 | 0 | — | 0 | |
| Net loss | −191 | −258 | −327 | −340 | −182 | |
| Net unrealized gain on available-for-sale investments | 358,000 | 866,000 | 9 | −7 | −3 | |
| Net comprehensive loss | −191 | −257 | −318 | −348 | −185 | |
| Net loss per share, basic (in dollars per share) | −0.87 | −1.32 | −2.09 | −2.38 | −1.34 | |
| Net loss per share, diluted (in dollars per share) | −0.87 | −1.32 | −2.09 | −2.38 | −1.34 | |
| Weighted-average number of shares used in computing net loss per share, basic (in shares) | 221 | 195 | 157 | 143 | 136 | |
| Weighted-average number of shares used in computing net loss per share, diluted (in shares) | 221 | 195 | 157 | 143 | 136 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2023 2023-09-30 | FY 2023 2023-06-30 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 52 | 75 | 83 | 69 | 155 | |
| Short-term investments | 199 | 217 | 366 | 396 | 337 | |
| Prepaid expenses and other current assets | 8 | 11 | 10 | 8 | 10 | |
| Total current assets | 258 | 303 | 459 | 473 | 502 | |
| Long-term investments | 8 | 81 | 0 | 32 | 53 | |
| Operating lease right-of-use asset | 40 | 45 | 64 | 79 | 80 | |
| Property and equipment, net | 73 | 86 | 99 | 103 | 106 | |
| Deposit placed in escrow | 23 | 21 | 0 | — | — | |
| Restricted cash | 10 | 10 | 10 | 10 | 10 | |
| Other long-term assets | 4 | 2 | 7 | 10 | 9 | |
| Total assets | 416 | 549 | 643 | 713 | 773 | |
| Accounts payable | 4 | 5 | 6 | 6 | 10 | |
| Accrued and other current liabilities | 28 | 30 | 31 | 31 | 44 | |
| Total current liabilities | 33 | 36 | 37 | 37 | 55 | |
| Lease liability, noncurrent | 75 | 83 | 88 | 90 | 92 | |
| Other long-term liabilities | 16 | 8 | 5 | 5 | 5 | |
| Total liabilities | 123 | 127 | 131 | 133 | 152 | |
| Commitments and Contingencies (Notes 6 and 7) | — | — | — | — | — | |
| Preferred stock, $0.001 par value: 10,000,000 authorized as of December 31, 2025 and December 31, 2024; no shares were issued and outstanding as of December 31, 2025 and December 31, 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value: 400,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 229,413,523 and 212,210,597 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively | 229,000 | 212,000 | 169,000 | 168,000 | 167,000 | |
| Additional paid-in capital | 2,303 | 2,242 | 2,075 | 2,059 | 2,039 | |
| Accumulated deficit | −2,011 | −1,820 | −1,562 | −1,476 | −1,414 | |
| Accumulated other comprehensive gain (loss) | 269,000 | −89,000 | −955,000 | −2 | −4 | |
| Total stockholders equity | 293 | 422 | 512 | 581 | 621 | |
| Total liabilities and stockholders equity | 416 | 549 | 643 | 713 | 773 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −191 | −258 | −327 | −340 | −182 | |
| Stock-based compensation | 38 | 52 | 66 | 84 | 81 | |
| Depreciation and amortization | 12 | 14 | 14 | — | — | |
| Net amortization/accretion on investment securities | −4 | −8 | −7 | 3 | 7 | |
| Impairment of equity investment and equity method investment | 0 | 2 | 7 | 0 | 0 | |
| Non-cash rent expense | 4 | 5 | 7 | 2 | 3 | |
| Non-cash collaboration revenue - related party | 0 | −14,000 | −63,000 | −104,000 | −76 | |
| Share of loss from equity method investments | 0 | 2 | 11 | — | — | |
| Deposit placed in escrow | −3 | −21 | 0 | — | — | |
| Prepaid expenses and other current assets | 3 | −492,000 | 1 | 3 | 3 | |
| Other long-term assets | −1 | 4 | −1 | −3 | −646,000 | |
| Accounts payable | −1 | −503,000 | −8 | 5 | −767,000 | |
| Accrued and other current liabilities | −3 | −1 | −7 | 2 | 4 | |
| Operating lease liabilities | −8 | −6 | −6 | — | — | |
| Other long-term liabilities | 1 | 259,000 | −611,000 | −2 | 910,000 | |
| Net cash used in operating activities | −149 | −200 | −238 | −221 | −185 | |
| Purchases of property and equipment | −386,000 | −694,000 | −2 | −5 | −21 | |
| Proceeds from sales of investments | 0 | 5 | 6 | 0 | 0 | |
| Proceeds from maturities of investments | 234 | 432 | 598 | 359 | 728 | |
| Purchase of investments | −138 | −361 | −439 | −248 | −526 | |
| Net cash provided by investing activities | 96 | 76 | 163 | 106 | 164 | |
| Proceeds from issuance of common stock upon exercise of stock options | 0 | 813,000 | 2 | 489,000 | 8 | |
| Proceeds from issuance of common stock under the employee stock purchase plan | 895,000 | 2 | 2 | 2 | 4 | |
| Proceeds from CIRM award | 7 | 2 | 0 | — | — | |
| Net cash provided by financing activities | 30 | 117 | 96 | 3 | 12 | |
| Net decrease in cash, cash equivalents and restricted cash | −24 | −8 | 21 | −111 | −9 | |
| Right-of-use asset obtained in exchange for lease liability | 0 | 2 | 0 | 31 | 20 | |
| Property and equipment purchases in accounts payable and accrued and other current liabilities | 107,000 | 64,000 | 0 | 678,000 | 2 | |
| Cash paid for amounts included in the measurement of lease liabilities | −13 | −13 | −12 | −10 | −6 |