ARDELYX, INC.
Business
Ardelyx is a commercial-stage biopharmaceutical company developing and commercializing innovative medicines addressing unmet medical needs. The company markets two approved therapies based on tenapanor: IBSRELA for irritable bowel syndrome with constipation and XPHOZAH to reduce serum phosphorus in chronic kidney disease patients on dialysis. Ardelyx also develops a next-generation NHE3 inhibitor and has collaboration agreements for tenapanor commercialization in Canada, Japan and China. The company operates as a single reportable segment focused on U.S. and ex-U.S. biopharmaceutical commercialization and development.
Summary from 10-K filed 2026-02-19
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 407 | 334 | 124 | 52 | 10 | |
| Cost of sales | 40 | 51 | 18 | 4 | 1 | |
| Research and development | 72 | 52 | 36 | 35 | 91 | |
| Selling, general and administrative | 337 | 259 | 134 | 77 | 72 | |
| Total costs and operating expenses | 448 | 362 | 188 | 112 | 163 | |
| Loss from operations | −41 | −28 | −63 | −64 | −154 | |
| Interest expense | −20 | −13 | −5 | −3 | — | |
| Non-cash interest expense related to the sale of future royalties | −8 | −7 | −4 | −2 | — | |
| Other income, net | 9 | 9 | 7 | 2 | 687,000 | |
| Loss before provision for income taxes | −61 | −39 | −66 | −67 | −158 | |
| Provision for income taxes | 969,000 | 266,000 | 547,000 | 8,000 | 4,000 | |
| Net loss | −62 | −39 | −66 | −67 | −158 | |
| Net loss per share of common stock - basic (in dollars per share) | −0.26 | −0.17 | −0.3 | −0.42 | −1.52 | |
| Net loss per share of common stock - diluted (in dollars per share) | −0.26 | −0.17 | −0.3 | −0.42 | −1.52 | |
| Shares used in computing net loss per share - basic (in shares) | 241 | 235 | 219 | 159 | 104 | |
| Shares used in computing net loss per share - diluted (in shares) | 241 | 235 | 219 | 159 | 104 | |
| Unrealized gains (losses) on available-for-sale securities | 141,000 | −167,000 | 278,000 | −48,000 | −2,000 | |
| Comprehensive loss | −61 | −39 | −66 | −67 | −158 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 68 | 65 | 21 | 96 | 72 | |
| Short-term investments | 197 | 185 | 163 | 28 | 44 | |
| Accounts receivable | 72 | 58 | 22 | 8 | 502,000 | |
| Inventory | 18 | 21 | 12 | 3 | 0 | |
| Prepaid commercial manufacturing | 14 | 16 | 19 | 14 | 9 | |
| Prepaid expenses and other current assets | 14 | 11 | 8 | 5 | 7 | |
| Total current assets | 382 | 356 | 246 | 154 | 134 | |
| Property and equipment, net | 2 | 1 | 1 | 1 | 2 | |
| Inventory, non-current | 105 | 70 | 37 | 25 | 0 | |
| Right-of-use assets | 5 | 2 | 6 | 9 | 13 | |
| Other assets | 7 | 5 | 4 | 881,000 | 1 | |
| Total assets | 502 | 436 | 298 | 190 | 150 | |
| Accounts payable | 19 | 16 | 11 | 11 | 4 | |
| Accrued compensation and benefits | 19 | 15 | 13 | 8 | 5 | |
| Current portion of operating lease liability | 1 | 2 | 4 | 4 | 3 | |
| Deferred revenue | 1 | 11 | 7 | 4 | 0 | |
| Accrued expenses and other current liabilities | 48 | 35 | 15 | 12 | 7 | |
| Total current liabilities | 89 | 78 | 50 | 66 | 53 | |
| Operating lease liability, net of current portion | 4 | 1 | 2 | 6 | 10 | |
| Long-term debt | 203 | 151 | 50 | 0 | 0 | |
| Deferred revenue, non-current | 14 | 7 | 9 | 9 | 5 | |
| Deferred royalty obligation related to the sale of future royalties | 26 | 26 | 20 | 11 | 0 | |
| Total liabilities | 335 | 262 | 131 | 92 | 67 | |
| Commitments and contingencies (Note 19) | — | — | — | — | — | |
| Common stock, $0.0001 par value per share; 500,000,000 shares authorized; 244,351,501 and 238,015,825 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively | 24,000 | 24,000 | 23,000 | 20,000 | 13,000 | |
| Additional paid-in capital | 1,114 | 1,059 | 1,013 | 879 | 796 | |
| Accumulated deficit | −947 | −885 | −846 | −780 | −713 | |
| Accumulated other comprehensive income | 198,000 | 57,000 | 224,000 | −54,000 | −6,000 | |
| Total stockholders equity | 167 | 173 | 167 | 98 | 83 | |
| Total liabilities and stockholders equity | 502 | 436 | 298 | 190 | 150 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization expense | 3 | 2 | 1 | 1 | 3 | |
| Non-cash lease expense | 2 | 4 | 4 | 3 | 3 | |
| Stock-based compensation | 49 | 37 | 14 | 11 | 12 | |
| Non-cash interest expense | 9 | 7 | 4 | 2 | 283,000 | |
| Non-cash royalty revenue related to the sale of future royalties | −9 | −3 | 0 | 0 | — | |
| Other, net | −4 | −5 | −3 | 685,000 | — | |
| Accounts receivable | −14 | −36 | −14 | −7 | −502,000 | |
| Inventory | −32 | −42 | −21 | −28 | 0 | |
| Prepaid commercial manufacturing | 2 | 7 | −10 | −4 | −9 | |
| Prepaid expenses and other assets | −4 | −5 | −6 | 2 | 502,000 | |
| Accounts payable | 3 | 5 | 279,000 | 7 | −1 | |
| Accrued compensation and benefits | 4 | 2 | 5 | 2 | −250,000 | |
| Operating lease liabilities | −2 | −5 | −4 | −3 | −3 | |
| Accrued and other liabilities | 15 | 21 | 4 | 4 | 1 | |
| Deferred revenue | −3 | 2 | 3 | 9 | 550,000 | |
| Net cash used in operating activities | −42 | −45 | −90 | −70 | −153 | |
| Proceeds from maturities and redemptions of investments | 211 | 178 | 84 | 67 | 126 | |
| Purchases of investments | −219 | −195 | −215 | −50 | −73 | |
| Purchases of property and equipment | −1 | −1 | −344,000 | −55,000 | −2 | |
| Net cash used in investing activities | −9 | −18 | −131 | 18 | 51 | |
| Proceeds from issuance of common stock in at the market offering, net of issuance costs | 0 | 0 | 119 | 72 | 101 | |
| Proceeds from 2022 Loan Agreement, net of costs | 49 | 99 | 22 | 27 | 0 | |
| Proceeds from the sale of future royalties, net of issuance costs | 0 | 0 | 5 | 10 | 0 | |
| Proceeds from issuance of common stock under equity incentive plans | 6 | 8 | 1 | 202,000 | 1 | |
| Payments of the previously outstanding exit fees | 0 | −1 | −2 | 0 | 0 | |
| Net cash provided by financing activities | 55 | 107 | 146 | 75 | 83 | |
| Net increase (decrease) in cash and cash equivalents | 3 | 43 | −75 | 24 | −19 | |
| Cash paid for interest | 16 | 11 | 4 | 3 | 3 | |
| Cash paid for income taxes | 485,000 | 266,000 | 51,000 | 6,000 | 4,000 | |
| Right-of-use assets obtained in exchange for lease obligations | 4 | 1 | 339,000 | 0 | 2 | |
| Issuance of common stock for services | 315,000 | 257,000 | 337,000 | 390,000 | 190,000 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is ARDELYX, INC.'s CIK number?
ARDELYX, INC.'s SEC CIK number is 0001437402 (1437402). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find ARDELYX, INC.'s SEC filings?
All of ARDELYX, INC.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did ARDELYX, INC. last report earnings?
ARDELYX, INC. (ARDX) most recently filed an earnings 8-K with the SEC on Apr 30, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001437402-26-000021). This is ARDELYX, INC.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is ARDELYX, INC.'s most recent earnings 8-K?
ARDELYX, INC.'s latest earnings 8-K (Item 2.02) was filed Apr 30, 2026 under accession 0001437402-26-000021. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View ARDELYX, INC.'s latest earnings 8-K →
Look up any company's CIK number →