Actinium Pharmaceuticals, Inc.
Business
Actinium Pharmaceuticals, Inc. develops targeted radiotherapies that use biologic molecules linked to radioisotopes to treat advanced and relapsed or refractory cancers. Its main product candidates include Actimab‑A (Ac‑225 CD33‑targeted therapy), Iomab‑ACT (I‑131 CD45 targeted conditioning), ATNM‑400 (Ac‑225 prostate cancer program) and the Iomab‑B program, supported by preclinical research and proprietary Ac‑225 cyclotron production. Key business areas comprise clinical development, preclinical R&D, in‑house and CDMO manufacturing, isotope production technology and strategic collaborations such as an NCI CRADA. Actinium conducts clinical trials and supplies investigational products through major cancer centers, CDMOs and clinical networks in the U.S., Canada and international markets including Europe.
Summary from filing dated 2025-03-31
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 90,000 | — | 81,000 | 1 | 1 | |
| Research and development, net of reimbursements | 21 | 30 | 39 | 23 | 18 | |
| General and administrative | 15 | 12 | 13 | 12 | 8 | |
| Total operating expenses | 36 | 42 | 52 | 35 | 26 | |
| Loss from operations | −36 | −42 | −52 | −34 | −25 | |
| Interest income net | 2 | 4 | 3 | — | — | |
| Total other income | 2 | 4 | 3 | 1 | 190,000 | |
| Net loss | −34 | −38 | −49 | −33 | −25 | |
| Net loss per common share basic (in Dollars per share) | −1.09 | −1.27 | −1.83 | −1.37 | −1.2 | |
| Net loss per common share diluted (in Dollars per share) | −1.09 | −1.27 | −1.83 | −1.37 | −1.2 | |
| Weighted average common shares outstanding basic (in Shares) | 31 | 30 | 27 | 24 | 21 | |
| Weighted average common shares outstanding diluted (in Shares) | 31 | 30 | 27 | 24 | 21 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 48 | 73 | 77 | 109 | 78 | |
| Prepaid expenses and other current assets | 1 | 2 | 2 | 2 | 1 | |
| Total Current Assets | 49 | 75 | 78 | 111 | 80 | |
| Property and equipment, net of accumulated depreciation of $1,064 and $891 | 295,000 | 364,000 | 550,000 | 604,000 | 340,000 | |
| Restricted cash long term | 335,000 | 324,000 | 313,000 | 302,000 | — | |
| Operating lease right-of-use assets | 2 | 2 | 2 | 2 | 241,000 | |
| Finance leases right-of-use assets | 10,000 | 20,000 | 30,000 | 3,000 | 58,000 | |
| Total Assets | 52 | 77 | 81 | 114 | 80 | |
| Accounts payable and accrued expenses | 7 | 8 | 8 | — | — | |
| Operating leases current liability | 711,000 | 569,000 | 530,000 | 494,000 | 245,000 | |
| Finance leases current liability | 11,000 | 11,000 | 11,000 | 4,000 | 62,000 | |
| Total Current Liabilities | 8 | 8 | 8 | 11 | 7 | |
| Long-term license revenue deferred | 35 | 35 | 35 | — | — | |
| Long-term operating lease obligations | 972,000 | 984,000 | 2 | 2 | — | |
| Long-term finance lease obligations | — | 9,000 | 19,000 | — | 3,000 | |
| Total Liabilities | 44 | 44 | 45 | 48 | 7 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, $0.001 par value; 50,000,000 shares authorized, 0 shares issued and outstanding | — | — | — | — | — | |
| Common stock, $0.001 par value; 1,000,000,000 shares authorized; 31,195,891 shares issued and outstanding at December 31, 2025 and 2024, respectively | 31,000 | 31,000 | 28,000 | 26,000 | 22,000 | |
| Additional paid-in capital | 418 | 409 | 374 | 355 | 329 | |
| Accumulated other comprehensive loss | −20,000 | — | — | — | — | |
| Accumulated deficit | −410 | −376 | −338 | −289 | −256 | |
| Total Stockholders Equity | 8 | 33 | 36 | 66 | 74 | |
| Total Liabilities and Stockholders Equity | 52 | 77 | 81 | 114 | 80 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 9 | 5 | 4 | 3 | 2 | |
| Depreciation expense | 173,000 | 197,000 | — | — | — | |
| Amortization of right-of-use assets | 648,000 | 614,000 | 583,000 | — | — | |
| Prepaid expenses and other current assets | 219,000 | −15,000 | 49,000 | −158,000 | −161,000 | |
| Accounts payable and accrued expenses | −346,000 | −387,000 | −2 | 5 | 1 | |
| Operating lease liabilities | −577,000 | −530,000 | −494,000 | −272,000 | — | |
| Net Cash Used In Operating Activities | −25 | −33 | −47 | 9 | −21 | |
| Purchase of property and equipment | −104,000 | −11,000 | −153,000 | −366,000 | −133,000 | |
| Net Cash Used In Investing Activities | −104,000 | −11,000 | −153,000 | −366,000 | −133,000 | |
| Payments on finance leases | −10,000 | −9,000 | −4,000 | −49,000 | −85,000 | |
| Proceeds from sales of shares of common stock, net of offering costs | — | 29 | 15 | 23 | 35 | |
| Restricted stock units withheld to cover tax obligations | −207,000 | — | — | — | — | |
| Proceeds from the exercise of stock options | — | 75,000 | 262,000 | — | 6,000 | |
| Net Cash (Used In) Provided By Financing Activities | −217,000 | 29 | 15 | 23 | 35 | |
| Effect of foreign currency rates on cash | 6,000 | — | — | — | — | |
| Net Change in Cash, Cash Equivalents and Restricted Cash | −25 | −4 | — | 31 | 14 | |
| Right-of-use assets obtained in exchange for lease liabilities | 708,000 | — | 30,000 | 3 | — |