Aura Biosciences, Inc.
Business
Aura Biosciences, Inc. is a clinical-stage biotechnology company developing precision therapies to treat solid tumors while preserving organ function, with lead candidate bel-sar in late-stage clinical development for primary choroidal melanoma and additional programs in ocular and bladder cancers. Its main product approach comprises virus-like drug conjugates (VDCs), including bel-sar, which are HPV-derived virus-like particles conjugated to light-activated cytotoxic molecules that induce acute necrosis and a secondary immune response. The company’s key development segments focus on ocular oncology (early-stage choroidal melanoma, metastases to the choroid, ocular surface tumors) and urologic oncology (non–muscle-invasive and muscle-invasive bladder cancer). Aura conducts global clinical trials and interacts primarily with ocular oncologists, urologic oncology centers and clinical research networks for patient access and potential targeted commercialization.
Summary from filing dated 2025-03-24
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 90 | 73 | 65 | 42 | 25 | |
| General and administrative | 22 | 23 | 20 | 18 | 10 | |
| Total operating expenses | 113 | 96 | 85 | 60 | 35 | |
| Total operating loss | −113 | −96 | −85 | −60 | −35 | |
| Interest income, including amortization and accretion income | 7 | 9 | 9 | 2 | 13,000 | |
| Other income (expense) | 77,000 | −120,000 | −76,000 | −14,000 | — | |
| Total other income | 7 | 9 | 9 | 2 | −1,000 | |
| Loss before income taxes | −106 | −87 | −76 | −59 | — | |
| Income tax provision, net | −100,000 | −100,000 | −100,000 | 0 | — | |
| Net loss | −106 | −87 | −76 | −59 | −35 | |
| Net loss per common share - basic | −1.76 | −1.75 | −1.93 | −1.96 | −8.95 | |
| Net loss per common share - diluted | −1.76 | −1.75 | −1.93 | −1.96 | −8.95 | |
| Weighted average common stock outstanding - basic | 60 | 50 | 40 | 30 | 5 | |
| Weighted average common stock outstanding - diluted | 60 | 50 | 40 | 30 | 5 | |
| Unrealized loss on marketable securities | −179,000 | −271,000 | 611,000 | −72,000 | — | |
| Currency translation adjustment | −186,000 | −5,000 | — | — | — | |
| Total other comprehensive loss | −365,000 | −276,000 | 611,000 | −72,000 | — | |
| Total comprehensive loss | −107 | −87 | −76 | −59 | −35 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 60 | 32 | 41 | 122 | 149 | |
| Marketable securities | 85 | 119 | 185 | 67 | — | |
| Prepaid expenses and other current assets | 5 | 10 | 6 | 8 | 5 | |
| Total current assets | 150 | 161 | 232 | 197 | 154 | |
| Restricted cash and deposits | 768,000 | 768,000 | 768,000 | 768,000 | 125,000 | |
| Right of use assets - operating lease | 16 | 17 | 19 | 21 | 950,000 | |
| Other long-term assets | 471,000 | 518,000 | 509,000 | 423,000 | — | |
| Property and equipment, net | 3 | 3 | 3 | 5 | 5 | |
| Total Assets | 169 | 183 | 255 | 224 | 160 | |
| Accounts payable | 2 | 2 | 2 | 3 | 2 | |
| Short-term operating lease liability | 3 | 3 | 3 | 3 | 615,000 | |
| Accrued expenses and other current liabilities | 14 | 9 | 8 | 5 | 4 | |
| Total current liabilities | 18 | 15 | 12 | 10 | 7 | |
| Long-term operating lease liability | 14 | 16 | 17 | 18 | 360,000 | |
| Total Liabilities | 33 | 31 | 29 | 28 | 8 | |
| Commitments and Contingencies (Note 12) | — | — | — | — | — | |
| Common stock, $0.00001 par value, 150,000,000 authorized at December 31, 2025 and December 31, 2024, and 63,587,777 and 49,998,279 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | — | — | — | — | — | |
| Additional paid-in capital | 617 | 526 | 513 | 407 | 304 | |
| Accumulated deficit | −480 | −374 | −287 | −211 | −152 | |
| Accumulated other comprehensive income (loss) | −102,000 | 263,000 | 539,000 | −72,000 | — | |
| Total Stockholders' Equity | 137 | 152 | 226 | 196 | 152 | |
| Total Liabilities and Stockholders' Equity | 169 | 183 | 255 | 224 | 160 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −106 | −87 | −76 | −59 | −35 | |
| Depreciation expense | 1 | 1 | 1 | 1 | 800,000 | |
| Accretion income on marketable securities | −2 | −5 | −4 | −527,000 | — | |
| Other non-cash items | 27,000 | −5,000 | — | — | — | |
| Stock-based compensation expense | 14 | 12 | 9 | 6 | 2 | |
| Non-cash lease expense | 2 | 1 | 2 | 968,000 | — | |
| Prepaid expenses and other assets | 4 | −4 | 4 | −3 | −4 | |
| Other long-term assets | 47,000 | −9,000 | −86,000 | −423,000 | — | |
| Accounts payable | −846,000 | 482,000 | −1 | 340,000 | 1 | |
| Accrued expenses and other liabilities | 4 | 2 | 3 | 234,000 | 2 | |
| Operating lease liabilities | −1 | −788,000 | −1 | −744,000 | — | |
| Net cash used in operating activities | −85 | −80 | −64 | −55 | −32 | |
| Purchases of property and equipment | −447,000 | −1 | −709,000 | −1 | −2 | |
| Purchases of marketable securities | −84 | −59 | −234 | −120 | — | |
| Proceeds from sale of marketable securities | — | −5,000 | — | — | — | |
| Maturities of marketable securities | 120 | 129 | 120 | 53 | — | |
| Net cash provided by investing activities | 36 | 69 | −114 | −68 | −2 | |
| Proceeds from exercise of stock options | 1 | 1 | 1 | 430,000 | 349,000 | |
| Proceeds from issuance of common stock from follow-on offering, net of issuance costs | 47 | 0 | — | 87 | 79 | |
| Proceeds from issuance of pre-funded warrants from follow-on offering, net of issuance costs | 14 | 0 | — | — | — | |
| Proceeds from issuance of common stock warrants from follow-on offering, net of issuance costs | 9 | 0 | — | — | — | |
| Proceeds from issuance of common stock under ATM facility, net of issuance costs | 6 | 0 | 3 | 9 | — | |
| Proceeds from ESPP purchases | 164,000 | 177,000 | 128,000 | — | — | |
| Net cash provided by financing activities | 77 | 2 | 97 | 96 | 166 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 28 | −9 | — | — | — | |
| Effect of exchange rate changes on cash and cash equivalents | −186,000 | 0 | — | — | — | |
| Purchases of property and equipment in accounts payable and accrued expenses and other liabilities | 91,000 | 35,000 | 94,000 | 180,000 | 386,000 |