Axsome Therapeutics, Inc.
Business
Axsome Therapeutics is a fully integrated biopharmaceutical company developing innovative medicines for central nervous system conditions. The company markets three FDA-approved products: AUVELITY for major depressive disorder, SUNOSI for excessive daytime sleepiness, and SYMBRAVO for acute migraine treatment. Axsome operates a commercial infrastructure in the United States and advances a pipeline of clinical-stage candidates including AXS-05 for Alzheimer's disease agitation and smoking cessation, solriamfetol for multiple neurological indications, AXS-12 for narcolepsy, AXS-14 for fibromyalgia, and AXS-17 for epilepsy, leveraging proprietary chemistry and formulation technologies.
Summary from 10-K filed 2026-02-23
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 638 | 386 | 271 | 50 | — | |
| Cost of revenue (excluding amortization and depreciation) | 47 | 33 | 26 | 5 | — | |
| Research and development | 183 | 187 | 98 | 58 | 58 | |
| Selling, general and administrative | 571 | 411 | 323 | 159 | 67 | |
| Loss (Gain) in fair value of contingent consideration | −2 | 28 | 49 | 3 | — | |
| Intangible asset amortization | 6 | 6 | 6 | 4 | — | |
| Total operating expenses | 805 | 666 | 502 | 230 | 125 | |
| Loss from operations | −167 | −281 | −232 | −180 | −125 | |
| Interest expense, net | −7 | −7 | −6 | −7 | −6 | |
| Loss on debt extinguishment | −10 | — | — | — | — | |
| Loss before income taxes | −184 | −287 | −238 | −187 | −130 | |
| Income tax benefit (expense) | 500,000 | −85,000 | −960,000 | — | — | |
| Net loss | −183 | −287 | −239 | −187 | −130 | |
| Net loss per common share, basic | −3.68 | −5.99 | −5.27 | −4.6 | −3.47 | |
| Net loss per common share, diluted | −3.68 | −5.99 | −5.27 | −4.6 | −3.47 | |
| Weighted average common shares outstanding, basic | 50 | 48 | 45 | 41 | 38 | |
| Weighted average common shares outstanding, diluted | 50 | 48 | 45 | 41 | 38 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 323 | 315 | 386 | 201 | 86 | |
| Accounts receivable, net | 224 | 142 | 95 | 38 | — | |
| Inventories, net | 28 | 16 | 15 | 4 | — | |
| Prepaid and other current assets | 14 | 12 | 8 | 3 | 45,286 | |
| Total current assets | 589 | 485 | 504 | 246 | 87 | |
| Equipment, net | 562,000 | 584,000 | 846,000 | 722,000 | 283,846 | |
| Right-of-use asset | 21 | 5 | 7 | 420,000 | 660,162 | |
| Goodwill | 12 | 12 | 12 | 10 | — | |
| Intangible asset, net | 41 | 47 | 53 | 60 | — | |
| Non-current inventory and other assets | 27 | 19 | 11 | 15 | 322,910 | |
| Total assets | 690 | 568 | 588 | 331 | 88 | |
| Accounts payable | 66 | 72 | 41 | 39 | 13 | |
| Accrued expenses and other current liabilities | 233 | 148 | 91 | 52 | 9 | |
| Operating lease liability, current portion | 434,000 | 2 | 1 | 425,000 | 620,675 | |
| Contingent consideration, current | 10 | 8 | 6 | 6 | — | |
| Short-term borrowings | 70 | 0 | — | — | — | |
| Total current liabilities | 379 | 230 | 139 | 97 | 23 | |
| Contingent consideration, non-current | 78 | 92 | 73 | 31 | — | |
| Loan payable, long-term | 118 | 181 | 178 | 94 | 49 | |
| Operating lease liability, long-term | 23 | 6 | 7 | — | — | |
| Finance lease liability, long-term | 4 | 3 | — | — | — | |
| Total liabilities | 602 | 511 | 397 | 222 | 72 | |
| Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding) | — | — | — | — | — | |
| Common stock, $0.0001 par value per share (150,000,000 shares authorized, 50,882,766 and 48,667,587 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively) | 5,000 | 5,000 | 5,000 | 4,000 | 3,782 | |
| Additional paid-in capital | 1,394 | 1,180 | 1,027 | 706 | 425 | |
| Accumulated deficit | −1,306 | −1,123 | −836 | −596 | −409 | |
| Total stockholders equity | 88 | 57 | 191 | 110 | 16 | |
| Total liabilities and stockholders equity | 690 | 568 | 588 | 331 | 88 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −183 | −287 | −239 | −187 | −130 | |
| Stock-based compensation expense | 94 | 85 | 63 | 38 | 21 | |
| Amortization of debt discount | 1 | 3 | 3 | 1 | 1 | |
| Depreciation | 503,000 | 532,000 | 459,000 | 263,000 | 76,000 | |
| Gain from lease modification | −2 | — | — | — | — | |
| Non-cash lease expense | 3 | 1 | 1 | 1 | 1 | |
| Right-of-use asset amortization for finance lease | 2 | 1 | — | — | — | |
| Accounts receivable, net | −82 | −47 | −57 | −38 | — | |
| Inventories, net | −11 | 744,000 | −8 | −1 | — | |
| Prepaid expenses and other current assets | −2 | −4 | −5 | −3 | 103,000 | |
| Non-current inventory and other assets | −5 | −3 | 4 | −4 | −6,000 | |
| Accounts payable | −6 | 31 | 2 | 25 | −355,000 | |
| Accrued expenses and other current liabilities | 84 | 56 | 36 | 44 | 582,000 | |
| Operating lease liability | −535,000 | −422,000 | 154,000 | — | — | |
| Net cash used in operating activities | −93 | −128 | −145 | −117 | −108 | |
| Purchases of equipment | −480,000 | −270,000 | −582,000 | −702,000 | −308,000 | |
| Net cash used in investing activities | −480,000 | −270,000 | −582,000 | −54 | −308,000 | |
| Proceeds from draw down of debt | 330 | — | 85 | 45 | — | |
| Payment of debt issuance costs | −4 | — | −1 | −487,000 | −309,000 | |
| Repayment of debt | −332 | — | — | — | — | |
| Payments on principal portion of finance lease obligation | −2 | −990,000 | — | — | — | |
| Proceeds from issuance of common stock upon financing | 68 | 41 | 259 | 244 | 7 | |
| Cash paid for common stock issuance costs | −1 | −816,000 | −16 | −7 | −223,000 | |
| Proceeds from issuance of common stock upon exercise of options and under employee stock purchase plan | 60 | 31 | 12 | 6 | — | |
| Payment of contingent consideration | −10 | −8 | −6 | −2 | — | |
| Payments of tax withholdings on stock awards | −7 | −4 | −2 | −532,000 | −176,000 | |
| Net cash provided by financing activities | 101 | 58 | 331 | 285 | 11 | |
| Net increase (decrease) in cash | 8 | −71 | 185 | 114 | −97 | |
| Interest paid | 15 | 20 | 17 | 8 | 5 | |
| Operating lease right-of-use asset obtained in exchange for operating lease liability | 24 | — | 8 | 561,000 | — | |
| Finance lease right-of-use asset obtained in exchange for finance lease liability | 5 | 5 | — | — | — | |
| Decrease in operating lease right-of-use asset due to lease modification | 5 | — | — | — | — | |
| Decrease in operating lease liability due to lease modification | 8 | — | — | — | — | |
| Issuance of warrants in connection with debt financing | — | — | 2 | 0 | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Axsome Therapeutics, Inc.'s CIK number?
Axsome Therapeutics, Inc.'s SEC CIK number is 0001579428 (1579428). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Axsome Therapeutics, Inc.'s SEC filings?
All of Axsome Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Axsome Therapeutics, Inc. last report earnings?
Axsome Therapeutics, Inc. (AXSM) most recently filed an earnings 8-K with the SEC on May 4, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-202506). This is Axsome Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Axsome Therapeutics, Inc.'s most recent earnings 8-K?
Axsome Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 4, 2026 under accession 0001193125-26-202506. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Axsome Therapeutics, Inc.'s latest earnings 8-K →
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