Axsome Therapeutics, Inc.
Business
Axsome Therapeutics, Inc. is a biopharmaceutical company focused on developing and delivering transformative medicines for central nervous system (CNS) conditions. It develops and commercializes innovative small‑molecule therapies, including approved products Auvelity, Sunosi, and Symbravo, and investigational candidates AXS‑05, AXS‑12, AXS‑14 and solriamfetol across indications such as major depressive disorder, narcolepsy, migraine, fibromyalgia, ADHD, binge eating disorder and shift work disorder. The business includes research and development, clinical development, regulatory strategy, intellectual property management and a U.S. commercial organization. Products are sold and distributed primarily in the United States, with selective licensing and partnering for Europe, Middle East/North Africa and other international territories.
Summary from filing dated 2025-02-18
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 638 | 386 | 271 | 50 | — | |
| Cost of revenue (excluding amortization and depreciation) | 47 | 33 | 26 | 5 | — | |
| Research and development | 183 | 187 | 98 | 58 | 58 | |
| Selling, general and administrative | 571 | 411 | 323 | 159 | 67 | |
| Loss (Gain) in fair value of contingent consideration | −2 | 28 | 49 | 3 | — | |
| Intangible asset amortization | 6 | 6 | 6 | 4 | — | |
| Total operating expenses | 805 | 666 | 502 | 230 | 125 | |
| Loss from operations | −167 | −281 | −232 | −180 | −125 | |
| Interest expense, net | −7 | −7 | −6 | −7 | −6 | |
| Loss on debt extinguishment | −10 | — | — | — | — | |
| Loss before income taxes | −184 | −287 | −238 | −187 | −130 | |
| Income tax benefit (expense) | 500,000 | −85,000 | −960,000 | — | — | |
| Net loss | −183 | −287 | −239 | −187 | −130 | |
| Net loss per common share, basic | −3.68 | −5.99 | −5.27 | −4.6 | −3.47 | |
| Net loss per common share, diluted | −3.68 | −5.99 | −5.27 | −4.6 | −3.47 | |
| Weighted average common shares outstanding, basic | 50 | 48 | 45 | 41 | 38 | |
| Weighted average common shares outstanding, diluted | 50 | 48 | 45 | 41 | 38 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 323 | 315 | 386 | 201 | 86 | |
| Accounts receivable, net | 224 | 142 | 95 | 38 | — | |
| Inventories, net | 28 | 16 | 15 | 4 | — | |
| Prepaid and other current assets | 14 | 12 | 8 | 3 | 45,286 | |
| Total current assets | 589 | 485 | 504 | 246 | 87 | |
| Equipment, net | 562,000 | 584,000 | 846,000 | 722,000 | 283,846 | |
| Right-of-use asset | 21 | 5 | 7 | 420,000 | 660,162 | |
| Goodwill | 12 | 12 | 12 | 10 | — | |
| Intangible asset, net | 41 | 47 | 53 | 60 | — | |
| Non-current inventory and other assets | 27 | 19 | 11 | 15 | 322,910 | |
| Total assets | 690 | 568 | 588 | 331 | 88 | |
| Accounts payable | 66 | 72 | 41 | 39 | 13 | |
| Accrued expenses and other current liabilities | 233 | 148 | 91 | 52 | 9 | |
| Operating lease liability, current portion | 434,000 | 2 | 1 | 425,000 | 620,675 | |
| Contingent consideration, current | 10 | 8 | 6 | 6 | — | |
| Short-term borrowings | 70 | 0 | — | — | — | |
| Total current liabilities | 379 | 230 | 139 | 97 | 23 | |
| Contingent consideration, non-current | 78 | 92 | 73 | 31 | — | |
| Loan payable, long-term | 118 | 181 | 178 | 94 | 49 | |
| Operating lease liability, long-term | 23 | 6 | 7 | — | — | |
| Finance lease liability, long-term | 4 | 3 | — | — | — | |
| Total liabilities | 602 | 511 | 397 | 222 | 72 | |
| Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding) | — | — | — | — | — | |
| Common stock, $0.0001 par value per share (150,000,000 shares authorized, 50,882,766 and 48,667,587 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively) | 5,000 | 5,000 | 5,000 | 4,000 | 3,782 | |
| Additional paid-in capital | 1,394 | 1,180 | 1,027 | 706 | 425 | |
| Accumulated deficit | −1,306 | −1,123 | −836 | −596 | −409 | |
| Total stockholders equity | 88 | 57 | 191 | 110 | 16 | |
| Total liabilities and stockholders equity | 690 | 568 | 588 | 331 | 88 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −183 | −287 | −239 | −187 | −130 | |
| Stock-based compensation expense | 94 | 85 | 63 | 38 | 21 | |
| Amortization of debt discount | 1 | 3 | 3 | 1 | 1 | |
| Depreciation | 503,000 | 532,000 | 459,000 | 263,000 | 76,000 | |
| Gain from lease modification | −2 | — | — | — | — | |
| Non-cash lease expense | 3 | 1 | 1 | 1 | 1 | |
| Right-of-use asset amortization for finance lease | 2 | 1 | — | — | — | |
| Accounts receivable, net | −82 | −47 | −57 | −38 | — | |
| Inventories, net | −11 | 744,000 | −8 | −1 | — | |
| Prepaid expenses and other current assets | −2 | −4 | −5 | −3 | 103,000 | |
| Non-current inventory and other assets | −5 | −3 | 4 | −4 | −6,000 | |
| Accounts payable | −6 | 31 | 2 | 25 | −355,000 | |
| Accrued expenses and other current liabilities | 84 | 56 | 36 | 44 | 582,000 | |
| Operating lease liability | −535,000 | −422,000 | 154,000 | — | — | |
| Net cash used in operating activities | −93 | −128 | −145 | −117 | −108 | |
| Purchases of equipment | −480,000 | −270,000 | −582,000 | −702,000 | −308,000 | |
| Net cash used in investing activities | −480,000 | −270,000 | −582,000 | −54 | −308,000 | |
| Proceeds from draw down of debt | 330 | — | 85 | 45 | — | |
| Payment of debt issuance costs | −4 | — | −1 | −487,000 | −309,000 | |
| Repayment of debt | −332 | — | — | — | — | |
| Payments on principal portion of finance lease obligation | −2 | −990,000 | — | — | — | |
| Proceeds from issuance of common stock upon financing | 68 | 41 | 259 | 244 | 7 | |
| Cash paid for common stock issuance costs | −1 | −816,000 | −16 | −7 | −223,000 | |
| Proceeds from issuance of common stock upon exercise of options and under employee stock purchase plan | 60 | 31 | 12 | 6 | — | |
| Payment of contingent consideration | −10 | −8 | −6 | −2 | — | |
| Payments of tax withholdings on stock awards | −7 | −4 | −2 | −532,000 | −176,000 | |
| Net cash provided by financing activities | 101 | 58 | 331 | 285 | 11 | |
| Net increase (decrease) in cash | 8 | −71 | 185 | 114 | −97 | |
| Interest paid | 15 | 20 | 17 | 8 | 5 | |
| Operating lease right-of-use asset obtained in exchange for operating lease liability | 24 | — | 8 | 561,000 | — | |
| Finance lease right-of-use asset obtained in exchange for finance lease liability | 5 | 5 | — | — | — | |
| Decrease in operating lease right-of-use asset due to lease modification | 5 | — | — | — | — | |
| Decrease in operating lease liability due to lease modification | 8 | — | — | — | — | |
| Issuance of warrants in connection with debt financing | — | — | 2 | 0 | — |