Candel Therapeutics, Inc.
Business
Candel Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing off-the-shelf viral immunotherapies that induce individualized systemic anti-tumor immune responses in solid tumors. Its main products are engineered adenovirus and herpes simplex virus (HSV) candidates, principally CAN-2409 (adenoviral plus prodrug) and CAN-3110 (HSV oncolytic), and preclinical assets from its enLIGHTEN™ discovery platform. Key business activities include clinical development, discovery platform research, manufacturing via third-party CDMOs, and strategic collaborations and licensing. It pursues regulatory approvals and clinical trials in the United States, Europe and Asia and distributes treatments via intratumoral administration through healthcare providers.
Summary from filing dated 2025-03-13
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 30 | 19 | 25 | 21 | 15 | |
| General and administrative | 18 | 14 | 14 | 14 | 11 | |
| Total operating expenses | 48 | 33 | 38 | 35 | 26 | |
| Loss from operations | −48 | −33 | −38 | −35 | −26 | |
| Grant income | 89,000 | — | — | 48,000 | 1 | |
| Interest income | 4 | 1 | 2 | — | — | |
| Interest expense | −2 | −2 | −3 | — | — | |
| Change in fair value of warrant liabilities | 8 | −21 | 966,000 | 16 | −11 | |
| Total other income (expense), net | 10 | −22 | 452,000 | 16 | −10 | |
| Net loss and comprehensive loss | −38 | −55 | −38 | −19 | −36 | |
| Net loss per share - basic | −0.72 | −1.74 | −1.31 | −0.65 | −1.91 | |
| Net loss per share - diluted | −0.72 | −1.74 | −1.31 | −0.65 | −1.91 | |
| Weighted-average common shares outstanding, basic | 53 | 32 | 29 | 29 | 19 | |
| Weighted-average common shares outstanding, diluted | 53 | 32 | 29 | 29 | 19 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 120 | 103 | 35 | 70 | 83 | |
| Prepaid expenses and other current assets | 2 | 1 | 1 | 2 | 2 | |
| Total current assets | 121 | 104 | 37 | 72 | 85 | |
| Fixed assets, net | 2 | 2 | 3 | 4 | 4 | |
| Lease right of use assets | 2 | 542,000 | 816,000 | 1 | — | |
| Restricted cash | 416,000 | 266,000 | 266,000 | 266,000 | 424,000 | |
| Other assets | 87,000 | 63,000 | 116,000 | — | — | |
| Total assets | 125 | 107 | 41 | 78 | 89 | |
| Accounts payable | 1 | 237,000 | 422,000 | 380,000 | 2 | |
| Accrued expenses | 7 | 5 | 4 | 5 | 3 | |
| Current portion of term loans | 0 | 10 | 9 | — | — | |
| Current portion of lease liability | 445,000 | 566,000 | 513,000 | 464,000 | — | |
| Warrant liabilities | 0 | 22 | 0 | — | — | |
| Other current liabilities | 89,000 | 0 | — | 48,000 | 334,000 | |
| Total current liabilities | 9 | 38 | 14 | 6 | 5 | |
| Deferred revenue | 89,000 | 0 | — | 144,000 | — | |
| Term loans, net of current portion | 46 | 2 | 12 | 20 | — | |
| Other long-term debt | 1 | 870,000 | 751,000 | 648,000 | 560,000 | |
| Lease liability, net of current portion | 1 | 407,000 | 973,000 | 1 | — | |
| Warrant liabilities | 16 | 0 | 916,000 | 2 | 18 | |
| Total liabilities | 73 | 41 | 28 | 30 | 25 | |
| Commitments and contingencies (Note 15) | — | — | — | — | — | |
| Preferred stock, $0.01 par value; 10,000,000 shares authorized at December 31, 2025 and 2024; no shares issued or outstanding at December 31, 2025 and 2024, respectively. | — | — | — | — | — | |
| Common stock, $0.01 par value; 150,000,000 shares authorized at December 31, 2025 and 2024; 55,020,911 and 46,933,088 shares issued at December 31, 2025 and 2024, respectively; and 54,898,303 and 46,810,480 shares outstanding at December 31, 2025 and 2024, respectively. | 550,000 | 469,000 | 290,000 | 290,000 | 286,000 | |
| Treasury stock (at cost) | −448,000 | −448,000 | −448,000 | −448,000 | — | |
| Additional paid-in capital | 282 | 259 | 150 | 147 | 144 | |
| Accumulated deficit | −230 | −192 | −137 | −99 | −80 | |
| Total stockholders' equity | 52 | 66 | 13 | 48 | 64 | |
| Total liabilities and stockholders' equity | 125 | 107 | 41 | 78 | 89 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −38 | −55 | −38 | −19 | −36 | |
| Depreciation expense | 800,000 | 1 | 1 | 800,000 | — | |
| Impairment of fixed assets | 90,000 | 41,000 | 390,000 | — | — | |
| Loss on the sale and disposal of fixed assets | 300,000 | 0 | 79,000 | — | — | |
| Non-cash stock compensation expense | 4 | 5 | 3 | 2 | 3 | |
| Non-cash lease expense | 321,000 | 274,000 | 240,000 | 209,000 | — | |
| Non-cash interest expense | 138,000 | 119,000 | 103,000 | 89,000 | 76,000 | |
| Accretion of debt discount | 360,000 | 270,000 | 323,000 | 291,000 | — | |
| Prepaid expenses and other current assets | −508,000 | 234,000 | 503,000 | 416,000 | −2 | |
| Other assets | −24,000 | 53,000 | −116,000 | — | — | |
| Accounts payable | 802,000 | −185,000 | 45,000 | −1 | 669,000 | |
| Accrued expenses | 2 | 757,000 | −301,000 | 1 | 297,000 | |
| Deferred income | 178,000 | — | −192,000 | 67,000 | −125,000 | |
| Lease liability | −509,000 | −513,000 | −464,000 | −464,000 | — | |
| Net cash used in operating activities | −38 | −27 | −34 | −31 | −22 | |
| Purchase of fixed assets | −587,000 | −16,000 | −457,000 | −1 | −2 | |
| Proceeds from the sale of fixed assets | 27,000 | — | 177,000 | — | — | |
| Net cash used in investing activities | −560,000 | −16,000 | −280,000 | −1 | −2 | |
| Proceeds from term loan, net of issuance costs | 48 | — | — | — | — | |
| Proceeds from issuance of common stock in registered direct offering, net of issuance costs | 14 | — | — | — | — | |
| Proceeds from option exercises | 516,000 | 2 | — | 64,000 | 35,000 | |
| Principal payments on term loan payable to a bank | −12 | −9 | — | — | — | |
| Net cash provided by financing activities | 56 | 94 | −121,000 | 20 | 72 | |
| Net increase in cash, cash equivalents and restricted cash | 17 | 67 | −35 | −13 | 48 | |
| Cash paid for interest | 1 | 2 | 2 | 1 | — | |
| Change in right of use asset and lease liability due to lease amendment | 1 | — | — | — | — | |
| Initial fair value of warrant liability in connection with debt financing | 2 | — | — | — | — | |
| Capital expenditures in accounts payable and accrued expenses | 132,000 | — | — | 69,000 | — | |
| Deferred offering issuance costs in accounts payable and accrued expenses | 93,000 | — | — | — | — |