Calidi Biotherapeutics, Inc.
Business
Calidi Biotherapeutics, Inc. is a clinical-stage immuno-oncology company developing proprietary allogeneic stem cell–based and enveloped virus platforms to potentiate and deliver oncolytic viruses to cancer patients. Its main products and services include cell-loaded oncolytic virotherapies such as NeuroNova™ (neural stem cells with oncolytic adenovirus), SuperNova™ (adipose-derived mesenchymal stem cells with vaccinia/CAL1 virus), and RTNova™ (enveloped oncolytic vaccinia virus) product candidates. Key business segments include proprietary platform R&D, StemVac subsidiary process development, and subsidiary Nova Cell technology services. Calidi distributes and advances products through clinical trials, collaborations with academic and contract manufacturing organizations, and intends regulatory pathways in the U.S. and other major oncology markets.
Summary from filing dated 2025-03-31
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|
| Research and development | −10 | −9 | −13 | −7 | |
| General and administrative | −11 | −13 | −16 | −16 | |
| Total operating expense | −20 | −22 | −29 | −23 | |
| Loss from operations | −20 | −22 | −29 | −23 | |
| Change in fair value of other liabilities and derivatives | 1,000 | 285,000 | — | — | |
| Change in fair value of other liabilities and derivatives related party | 1,000 | 39,000 | — | — | |
| Grant income | 50,000 | 181,000 | 3 | — | |
| Gain on sale of investment in Nova Cell | 244,000 | — | — | — | |
| Other income, net | 103,000 | 9,000 | −51,000 | −5,000 | |
| Total other income (expenses), net | 192,000 | −419,000 | −208,000 | −2 | |
| LOSS BEFORE INCOME TAXES | −20 | −22 | −29 | −25 | |
| Income tax provision | −15,000 | −14,000 | −16,000 | −11,000 | |
| NET LOSS | −20 | −22 | −29 | — | |
| Net loss attributable to noncontrolling interest | −157,000 | −66,000 | — | — | |
| NET LOSS ATTRIBUTABLE TO CONTROLLING INTEREST | −20 | −22 | −29 | −25 | |
| Deemed dividend on warrants | −6 | −2 | — | — | |
| NET LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS | −26 | −24 | −29 | — | |
| Net loss per share, basic | −5.95 | −35.7 | −17.33 | 2.99 | |
| Net loss per share, diluted | −5.95 | −35.7 | −17.33 | 2.99 | |
| Weighted average common shares outstanding, basic | 4,302 | 667 | 2 | 9 | |
| Weighted average common shares outstanding, diluted | 4,302 | 667 | 2 | 9 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash | 6 | 10 | 2 | 372,000 | 1 | |
| Prepaid expenses and other current assets | 656,000 | 636,000 | 2 | 414,000 | — | |
| Total current assets | 6 | 10 | 4 | 786,000 | 1 | |
| Machinery and equipment, net | 781,000 | 869,000 | — | — | — | |
| Operating lease right-of-use assets, net | 2 | 3 | 4 | 199,000 | — | |
| Other noncurrent assets | 138,000 | 152,000 | 373,000 | 725,000 | — | |
| TOTAL ASSETS | 9 | 14 | 10 | 3 | 232 | |
| Finance lease liability, current | 111,000 | 66,000 | 81,000 | 72,000 | — | |
| Operating lease right-of-use liability, current | 1 | 1 | 1 | 44,000 | — | |
| Total current liabilities | 4 | 9 | 10 | 43 | 410,985 | |
| Operating lease right-of-use liability, noncurrent | 277,000 | 2 | 3 | 305,000 | — | |
| Finance lease liability, noncurrent | 171,000 | 145,000 | 216,000 | 142,000 | — | |
| Promissory note | 600,000 | 600,000 | — | — | — | |
| Warrant liability | 107,000 | 119,000 | 623,000 | — | — | |
| Related party warrant liability | 8,000 | 9,000 | 48,000 | — | — | |
| TOTAL LIABILITIES | 5 | 12 | 18 | 43 | 16 | |
| Commitments and contingencies (Note 11) | — | — | — | — | — | |
| Common stock, $0.0001 par value, 330,000 shares authorized; 7,217 and 1,730 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 1,000 | — | 1,000 | 2,000 | — | |
| Additional paid-in capital | 145 | 123 | 91 | 20 | 0 | |
| Accumulated other comprehensive loss, net of tax | −13,000 | −28,000 | −47,000 | −14,000 | — | |
| Accumulated deficit | −142 | −122 | −100 | −70 | −15 | |
| Total stockholders equity | 4 | 2 | −8 | −50 | −32 | |
| Noncontrolling interest | — | 434,000 | — | — | — | |
| Total equity | 4 | 2 | −8 | −50 | — | |
| TOTAL LIABILITIES AND TOTAL EQUITY | 9 | 14 | 10 | 3 | 232 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|
| Depreciation and amortization expense | 2 | 2 | — | — | |
| Amortization of debt discount and financing costs | — | 45,000 | 432,000 | 123,000 | |
| Stock-based compensation | 2 | 3 | 5 | 5 | |
| Change in fair value of other liabilities and derivatives | −2,000 | −324,000 | — | — | |
| Prepaid expenses and other current assets | −42,000 | 2 | −2 | 170,000 | |
| Accounts payable | −1 | −628,000 | −6 | 2 | |
| Accrued expenses and other current liabilities | −2 | −2 | 1 | 2 | |
| Operating lease right of use liability | −1 | −1 | −628,000 | — | |
| Net cash used in operating activities | −21 | −20 | −27 | −13 | |
| Purchases of machinery and equipment | −120,000 | −16,000 | −585,000 | −428,000 | |
| Cash disposed in sale of investment in Nova Cell | −50,000 | — | — | — | |
| Net cash used in investing activities | −170,000 | −16,000 | −478,000 | −494,000 | |
| Proceeds from public offerings | 10 | 14 | — | — | |
| Proceeds from warrant inducement financing | 4 | 2 | — | — | |
| Proceeds from registered direct offering | 4 | — | — | — | |
| Proceeds from at the market offering | 3 | 3 | — | — | |
| Proceeds from exercise of pre-funded warrants | 5,000 | 2,000 | — | — | |
| Repayment of financing lease obligations | −90,000 | −82,000 | −101,000 | −81,000 | |
| Repayment of principal on term notes payable | −200,000 | −300,000 | −1 | −38,000 | |
| Repayment of principal on related party bridge loan payable | −200,000 | — | — | — | |
| Payment of financing costs | −846,000 | −2 | −2 | −58,000 | |
| Repayment of principal on related party term notes payable | −2 | — | — | — | |
| Proceeds from issuance of noncontrolling interest in Nova Cell | — | 2 | — | — | |
| Proceeds from issuance of convertible notes payable | — | 3 | — | — | |
| Related party proceeds from issuance of loan payable | — | 200,000 | — | 3 | |
| Proceeds from issuance of promissory note | — | 600,000 | — | — | |
| Proceeds from issuance of common stock and warrants per subscription agreement | — | 1 | — | — | |
| Proceeds from exercise of common stock warrants | — | 5 | — | — | |
| Repayment of convertible note payable | — | −2 | — | — | |
| Payment of debt issuance costs | — | −9,000 | — | — | |
| Net cash provided by financing activities | 17 | 27 | 29 | 12 | |
| Effect of exchange rate changes on cash | 14,000 | −13,000 | −6,000 | — | |
| NET (DECREASE) INCREASE IN CASH AND RESTRICTED CASH | −4 | 8 | 2 | −968,761 | |
| Cash paid for interest | 1 | 140,000 | 404,000 | 35,000 | |
| Cash paid for income taxes | 17,000 | 14,000 | — | — | |
| Machinery and equipment acquired through financing leases | 152,000 | — | 180,000 | 198,000 | |
| Financing fees included in accounts payable and accrued liabilities | 27,000 | −91,000 | — | — | |
| Issuance of common stock per conversion of convertible note | — | 3 | — | — | |
| Issuance of convertible note for legal settlement | — | 2 | — | — | |
| Issuance of common stock in lieu of cash for services | — | 289,000 | — | 205,000 | |
| Related party issuance of common stock in lieu of cash for services | — | 80,000 | — | — | |
| Issuance of common stock and warrants for legal settlement | — | 308,000 | — | — | |
| Debt discount on Convertible Notes | — | 109,000 | — | — | |
| Issuance of common stock in lieu of cash for SEPA commitment fee | — | 81,000 | — | — | |
| Issuance of restricted stock units for liability settlement | — | 133,000 | — | — |