COMPASS Pathways plc
Business
Compass Pathways plc is a biotechnology company focused on accelerating patient access to evidence-based innovations in mental health. It develops COMP360, a pharmaceutical‑grade crystalline psilocybin formulation, and delivers associated psychological support and digital tools used in its clinical protocols. Its operations encompass clinical development (Phase 2 and Phase 3 trials) across treatment‑resistant depression, PTSD and other indications, investigator‑initiated and mechanistic studies, manufacturing partnerships and digital initiatives. The company conducts multinational trials and collaborates with academic centers, healthcare delivery partners and CDMOs, distributing investigational product through clinical sites and Centers of Excellence.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 118 | 119 | 88 | 65 | 44 | |
| General and administrative | 61 | 59 | 49 | 45 | 39 | |
| Total operating expenses | 179 | 178 | 137 | 110 | 83 | |
| LOSS FROM OPERATIONS: | −179 | −178 | −137 | −110 | −83 | |
| Fair value change of warrant liabilities | −123 | 0 | — | — | — | |
| Benefit from R&D tax credit | 4 | 21 | 13 | 14 | 10 | |
| Interest income | 7 | 8 | 5 | — | — | |
| Interest expense | −5 | −4 | −2 | — | — | |
| Foreign exchange gains (losses) | 3 | −1 | 4 | 821,000 | 2 | |
| Other income | 1 | 823,000 | 255,000 | — | — | |
| Total other (expense) income, net | −111 | 25 | 19 | 19 | 12 | |
| Loss before income taxes | −290 | −154 | −118 | −91 | −72 | |
| Income tax benefit (expense) | 2 | −2 | −780,000 | −408,000 | −199,000 | |
| Net loss | −288 | −155 | −119 | −92 | −72 | |
| Net loss per share attributable to ordinary shareholders - basic (in dollars per share) | −3.08 | −2.3 | −2.32 | −2.16 | −1.79 | |
| Net loss per share attributable to ordinary shareholders - diluted (in dollars per share) | −3.08 | −2.3 | −2.32 | −2.16 | −1.79 | |
| Weighted average ordinary shares outstanding - basic (in shares) | 94 | 67 | 51 | 42 | 40 | |
| Weighted average ordinary shares outstanding - diluted (in shares) | 94 | 67 | 51 | 42 | 40 | |
| Foreign exchange translation adjustment | 1 | 732,000 | −59,000 | — | — | |
| Comprehensive loss | −286 | −154 | −119 | −117 | −77 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 150 | 165 | 220 | 143 | 273 | |
| Restricted cash | 379,000 | 389,000 | 440,000 | 175,000 | 104,000 | |
| Prepaid expenses and other current assets | 42 | 36 | — | — | — | |
| Total current assets | 191 | 201 | 261 | 192 | 295 | |
| Operating lease right-of-use assets | 3 | 2 | 4 | 2 | 4 | |
| Deferred tax assets | 4 | 4 | 3 | 2 | 766,000 | |
| Long-term prepaid expenses and other assets | 12 | 7 | 7 | 1 | 213,000 | |
| Total assets | 210 | 214 | 276 | 197 | 301 | |
| Accounts payable | 15 | 12 | 6 | 5 | 3 | |
| Accrued expenses and other liabilities | 9 | 14 | 11 | 9 | 10 | |
| Debt, current portion | 18 | 6 | 0 | — | — | |
| Operating lease liabilities - current | 2 | 2 | 2 | 2 | 2 | |
| Warrant liabilities | 204 | 93 | — | — | — | |
| Total current liabilities | 248 | 34 | 20 | 16 | 15 | |
| Debt, non-current portion | 14 | 25 | 29 | — | — | |
| Operating lease liabilities - non-current | 1 | 303,000 | 2 | 418,000 | 1 | |
| Total liabilities | 263 | 59 | 50 | 16 | 16 | |
| Commitments and contingencies (Note 14) | — | — | — | — | — | |
| Ordinary shares, 0.008 par value; 96,085,785 and 68,552,215 shares authorized, issued and outstanding at December 31, 2025 and 2024, respectively | 973,000 | 702,000 | 635,000 | — | — | |
| Additional paid-in capital | 784 | 705 | 622 | 459 | 445 | |
| Accumulated other comprehensive loss | −15 | −16 | −17 | −17 | 9 | |
| Accumulated deficit | −823 | −535 | −380 | −261 | −170 | |
| Total shareholders' (deficit)/equity | −53 | 155 | 226 | 181 | 284 | |
| Total liabilities and shareholders' (deficit)/equity | 210 | 214 | 276 | 197 | 301 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 216,000 | 233,000 | 242,000 | — | — | |
| Non-cash interest | 1 | 1 | 636,000 | 0 | 0 | |
| Non-cash gain (loss) on foreign currency remeasurement | −1 | 755,000 | −3 | 1 | 22,000 | |
| Non-cash share-based compensation | 14 | 20 | 17 | 13 | 9 | |
| Non-cash lease expenses | 2 | 2 | 2 | 2 | 2 | |
| Transaction costs allocated to warrants | 6 | 0 | — | — | — | |
| Prepaid expenses and other current assets | −3 | 3 | 10 | −29 | −9 | |
| Deferred and prepaid tax assets | 23,000 | 686,000 | −2 | −2 | −877,000 | |
| Other assets | −5 | 135,000 | −6 | −307,000 | −160,000 | |
| Operating lease liabilities | −2 | −2 | −2 | −2 | −2 | |
| Accounts payable | 2 | 7 | 864,000 | 2 | −163,000 | |
| Accrued expenses and other liabilities | −6 | 3 | 2 | −314,000 | 5 | |
| Net cash used in operating activities | −157 | −119 | −97 | −105 | −68 | |
| Proceeds from issuance of ordinary shares and Pre-funded Warrants, net of issuance costs | 140 | 26 | 145 | 440,000 | 155 | |
| Proceeds from the exercise of warrants | 0 | 37 | 0 | — | — | |
| Proceeds from the vesting of restricted share units | 1,000 | 0 | — | — | — | |
| Payments of withholding tax on stock award | 0 | −239,000 | −265,000 | 0 | 0 | |
| Proceeds from the issuance of shares under the employee share purchase plan | 319,000 | 365,000 | 351,000 | 199,000 | 0 | |
| Proceeds from exercise of options | 35,000 | 221,000 | 2,000 | 401,000 | 2 | |
| Net cash provided by financing activities | 141 | 64 | 174 | 1 | 157 | |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | 1 | 194,000 | 867,000 | −25 | −6 | |
| Net (decrease)/increase in cash, cash equivalents and restricted cash | −15 | −55 | 77 | −130 | 83 | |
| Cash paid for interest | 3 | 3 | 1 | 0 | 0 | |
| Cash paid for taxes | 755,000 | 1 | 2 | — | — |