Cogent Biosciences, Inc.
Business
Cogent Biosciences, Inc. is a clinical-stage biotechnology company that discovers and develops precision small-molecule therapies for genetically defined diseases. Its main product candidates include bezuclastinib, a selective KIT inhibitor for systemic mastocytosis and GIST, and CGT4859, a reversible, selective FGFR2 inhibitor, alongside preclinical programs targeting ErbB2, PI3Kα and KRAS. The company organizes activities across clinical development, preclinical research (the Cogent Research Team), licensing and intellectual property management, and outsourced manufacturing. It conducts global clinical trials and regulatory interactions and relies on third-party manufacturers and collaborative channels for supply and distribution.
Summary from filing dated 2025-02-25
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 270 | 233 | 174 | 122 | 56 | |
| General and administrative | 64 | 43 | 34 | 26 | 20 | |
| Total operating expenses | 333 | 276 | 208 | 148 | 76 | |
| Loss from operations | −333 | −276 | −208 | −148 | −76 | |
| Interest income | 15 | 18 | 13 | 4 | 467,000 | |
| Interest expense | −3 | — | — | — | — | |
| Loss on debt extinguishment | −7 | 0 | 0 | — | — | |
| Change in fair value of CVR liability | 0 | 0 | 2 | 1 | 343,000 | |
| Other income (expense), net | −20,000 | 2 | 943,000 | — | — | |
| Total other income, net | 4 | 20 | 16 | 8 | 3 | |
| Net loss | −329 | −256 | −192 | −140 | −72 | |
| Net loss per share, basic | −2.16 | −1.94 | −1.94 | −1.73 | −1.87 | |
| Net loss per share, diluted | −2.16 | −1.94 | −1.94 | −1.73 | −1.87 | |
| Weighted average common stock outstanding, basic | 129 | 104 | 80 | 59 | 39 | |
| Weighted average common stock outstanding, diluted | 129 | 104 | 80 | 59 | 39 | |
| Net unrealized gains (losses) on marketable securities | −92,000 | 201,000 | 350,000 | −104,000 | 0 | |
| Total other comprehensive income (loss) | −92,000 | 201,000 | 350,000 | −104,000 | 0 | |
| Comprehensive loss | −329 | −256 | −192 | −140 | −72 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 312 | 98 | 53 | 140 | 220 | |
| Short-term marketable securities | 589 | 189 | 212 | 119 | 0 | |
| Prepaid expenses and other current assets | 10 | 9 | 5 | 4 | 3 | |
| Total current assets | 910 | 296 | 271 | 265 | 223 | |
| Operating lease, right-of-use assets | 18 | 20 | 22 | 23 | 3 | |
| Property and equipment, net | 5 | 6 | 8 | 8 | 2 | |
| Restricted cash | 416,000 | 0 | — | — | 1 | |
| Other assets | 3 | 5 | 5 | 5 | 4 | |
| Total assets | 938 | 328 | 313 | 301 | 232 | |
| Accounts payable | 10 | 12 | 11 | 6 | 3 | |
| Accrued expenses and other current liabilities | 53 | 42 | 26 | 18 | 8 | |
| Operating lease liabilities | 2 | 2 | 1 | 1 | 2 | |
| Total current liabilities | 64 | 56 | 38 | 27 | 17 | |
| Convertible senior notes, net | 223 | 0 | — | — | — | |
| Operating lease liabilities, net of current portion | 14 | 16 | 17 | 18 | 831,000 | |
| Other liabilities | 33,000 | 0 | — | — | — | |
| Total liabilities | 301 | 72 | 56 | 45 | 18 | |
| Commitments and contingencies (Note 9) | — | — | — | — | — | |
| Preferred stock, value | — | — | — | — | — | |
| Common stock, $0.001 par value; 300,000,000 shares authorized; 160,980,024 shares and 110,461,729 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 161,000 | 110,000 | 86,000 | 70,000 | 44,000 | |
| Additional paid-in capital | 1,735 | 1,005 | 801 | 601 | 400 | |
| Accumulated other comprehensive income | 355,000 | 447,000 | 246,000 | −104,000 | — | |
| Accumulated deficit | −1,188 | −859 | −604 | −411 | −271 | |
| Total stockholders equity | 636 | 256 | 258 | 256 | 214 | |
| Total liabilities and stockholders equity | 938 | 328 | 313 | 301 | 232 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −329 | −256 | −192 | −140 | −72 | |
| Depreciation expense | 3 | 2 | 2 | 842,000 | — | |
| Stock-based compensation expense | 46 | 40 | 31 | 18 | 12 | |
| Amortization of right-of-use operating lease assets | 2 | 2 | 1 | 5 | 2 | |
| Net amortization (accretion) of premiums (discounts) on marketable securities | −2 | −8 | −5 | −2 | 0 | |
| Loss on disposal of property and equipment | 0 | 0 | 8,000 | 0 | 0 | |
| Amortization of debt discount and issuance costs | 601,000 | 0 | 0 | — | — | |
| Prepaid expenses and other current assets | −195,000 | −4 | −626,000 | −1 | −227,000 | |
| Other assets | 2 | 2,000 | −119,000 | −1 | −4 | |
| Accounts payable | −3 | 1 | 5 | 2 | 3 | |
| Accrued expenses and other current liabilities | 11 | 16 | 8 | 10 | 3 | |
| Operating lease liability | −2 | −1 | −796,000 | −9 | −2 | |
| Other liabilities | 33,000 | 0 | 0 | — | — | |
| Net cash used in operating activities | −264 | −208 | −154 | −119 | −59 | |
| Purchases of property and equipment | −2 | −573,000 | −3 | −7 | −2 | |
| Purchases of marketable securities | −687 | −256 | −349 | −178 | 0 | |
| Maturities and sales of marketable securities | 289 | 294 | 254 | 60 | 0 | |
| Net cash provided by (used in) investing activities | −400 | 38 | −98 | −125 | −2 | |
| Proceeds from long-term debt | 49 | 0 | 0 | — | — | |
| Repayment of long-term debt | −55 | 0 | 0 | — | — | |
| Proceeds from convertible senior notes | 223 | 0 | 0 | — | — | |
| Payment of debt issuance costs | −3 | 0 | 0 | — | — | |
| Proceeds from issuance of common stock under ATM, net of issuance costs of $4.9 million | 159 | 0 | 0 | 0 | 38 | |
| Proceeds from issuance of common stock and Series B non-voting convertible preferred stock in connection with the Private Placement, net of offering costs $11.7 million | 0 | 213 | 0 | 0 | — | |
| Taxes paid related to net share settlement of equity awards | −49 | 0 | 0 | — | — | |
| Proceeds from issuance of common stock upon stock option exercises | 12 | 199,000 | 965,000 | 1 | 24,000 | |
| Proceeds from issuance of stock from employee stock purchase plan | 1 | 916,000 | 752,000 | 351,000 | 31,000 | |
| Net cash provided by financing activities | 878 | 214 | 164 | 164 | 38 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 214 | 45 | −88 | −80 | −23 | |
| Cash paid for interest | 2 | 0 | 0 | — | — | |
| Debt discount included in accrued expenses and other liabilities | 20,000 | 0 | 0 | — | — | |
| Offering costs included in accounts payable and accrued expenses | 64,000 | 49,000 | 30,000 | 30,000 | 0 | |
| Property & equipment included in accounts payable and accrued expenses | 0 | 0 | 43,000 | 58,000 | 0 |