Corbus Pharmaceuticals Holdings, Inc.
Business
Corbus Pharmaceuticals Holdings, Inc. is an oncology and obesity company that discovers and develops therapeutic drug candidates targeting well-understood biological pathways. Its main product candidates include CRB-701, a next‑generation Nectin‑4 antibody‑drug conjugate with an MMAE payload; CRB‑601, an anti‑αvβ8 integrin monoclonal antibody that blocks TGFβ activation; and CRB‑913, a peripherally restricted CB1 receptor inverse agonist for obesity. The company organizes around preclinical research, clinical development and regulatory activities, intellectual property management, and licensing/partnering. It conducts clinical trials and has licensed commercialization rights and clinical activities across the U.S., Canada, the European Union, the U.K., Australia and China while relying on third‑party contract manufacturers and partners for supply and distribution.
Summary from filing dated 2025-03-11
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 70 | 32 | 31 | 16 | 36 | |
| General and administrative | 15 | 16 | 14 | 19 | 20 | |
| Total operating expenses | 85 | 49 | 45 | 40 | 57 | |
| Operating loss | −85 | −49 | −45 | −40 | −56 | |
| Interest and investment income, net | 6 | 6 | 2 | — | — | |
| Interest expense | 0 | −2 | −4 | — | — | |
| Other income, net | 1 | 4 | 3 | −48,773 | 12 | |
| Total other income, net | 7 | 9 | 474,000 | −3 | 10 | |
| Net loss | −79 | −40 | −45 | −42 | −46 | |
| Net loss per share, basic | −5.9 | −3.68 | −10.31 | −10.15 | −11.15 | |
| Net loss per share of common stock diluted | −5.9 | −3.68 | −10.31 | −10.15 | −11.15 | |
| Weighted average number of common shares outstanding, basic | 13 | 11 | 4 | 4 | 4 | |
| Weighted average number of common shares outstanding, diluted | 13 | 11 | 4 | 4 | 4 | |
| Net Income (Loss) | −79 | −40 | −45 | −42 | −46 | |
| Change in unrealized (loss) gain on marketable debt securities | −88,000 | 36,000 | 125,000 | −63,647 | −62,445 | |
| Total other comprehensive (loss) income | −88,000 | 36,000 | 125,000 | −63,647 | −62,445 | |
| Total comprehensive loss | −79 | −40 | −44 | −42 | −46 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 28 | 17 | 14 | 17 | 25 | |
| Investments | 135 | 132 | 7 | 42 | 73 | |
| Restricted cash | 670,000 | 285,000 | 192,000 | 192,475 | 192,475 | |
| Prepaid expenses and other current assets | 3 | 4 | 2 | 791,616 | 2 | |
| Total current assets | 167 | 153 | 24 | 60 | 100 | |
| Restricted cash | 0 | 385,000 | 478,000 | 477,425 | 477,425 | |
| Property and equipment, net | 159,000 | 385,000 | 973,000 | 2 | 2 | |
| Operating lease right-of-use assets | 1 | 2 | 3 | 4 | 5 | |
| Total assets | 168 | 156 | 28 | 66 | 108 | |
| Accounts payable | 2 | 5 | 3 | 2 | 2 | |
| Accrued expenses | 17 | 5 | 11 | 6 | 10 | |
| Operating lease liabilities, current | 2 | 2 | 1 | 1 | 1 | |
| Total current liabilities | 21 | 12 | 32 | 13 | 17 | |
| Operating lease liabilities, noncurrent | 0 | 2 | 3 | 5 | 6 | |
| Total liabilities | 21 | 13 | 35 | 33 | 39 | |
| Preferred stock, $0.0001 par value; 10,000,000 shares authorized, no shares issued and outstanding at December 31, 2025 and December 31, 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value; 300,000,000 shares authorized,17,611,511 and 12,179,482 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 2,000 | 1,000 | 0 | 417 | 416 | |
| Additional paid-in capital | 703 | 619 | 430 | 425 | 419 | |
| Accumulated deficit | −555 | −477 | −437 | −392 | −350 | |
| Accumulated other comprehensive loss | −53,000 | 35,000 | −1,000 | −126,092 | −62,445 | |
| Total stockholders equity | 148 | 142 | −7 | 33 | 69 | |
| Total liabilities and stockholders equity | 168 | 156 | 28 | 66 | 108 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 6 | 6 | 3 | 6 | 9 | |
| Depreciation expense | 233,000 | 588,000 | 641,000 | 762,995 | 999,817 | |
| Net amortization of premiums and discounts on investments | −1 | −3 | −506,000 | 124,875 | — | |
| Amortization of debt discount | 0 | 396,000 | 824,000 | 742,478 | 700,613 | |
| Other | −229,000 | 189,000 | −19,000 | — | — | |
| Decrease (increase) in prepaid expenses and other current assets | 634,000 | −1 | −1 | — | — | |
| Decrease in other assets | 0 | 212,000 | −57,000 | — | — | |
| Decrease in operating lease right-of-use asset | 1 | 930,000 | — | — | — | |
| Decrease in other long-term liabilities | 0 | −44,000 | 22,000 | — | — | |
| (Decrease) increase in accounts payable | −2 | 2 | 1 | −256,835 | −6 | |
| Increase (decrease) in accrued expenses | 11 | −6 | 5 | −4 | −12 | |
| Decrease in operating lease liabilities | −2 | −1 | −1 | −1 | −1 | |
| Net cash used in operating activities | −64 | −42 | −36 | −38 | −48 | |
| Purchases of property and equipment | −7,000 | 0 | 0 | −13,449 | −54,172 | |
| Purchases of investments | −163 | −181 | −34 | −86 | −87 | |
| Proceeds from sales and maturities of investments | 161 | 59 | 70 | 116 | 14 | |
| Net cash used in investing activities | −2 | −121 | 36 | 30 | −73 | |
| Proceeds from issuance of common stock and pre-funded warrants, net | 77 | 182 | 53,000 | — | 63 | |
| Repayment of short-term borrowings | 0 | −301,000 | −426,000 | −866,865 | −926,595 | |
| Repayment of long-term borrowings | 0 | −15 | −3 | −2 | — | |
| Net cash provided by (used in) financing activities | 77 | 167 | −3 | −533,615 | 61 | |
| Net increase in cash, cash equivalents, and restricted cash | 11 | 3 | −3 | −8 | −61 | |
| Cash paid during the period for interest | 0 | 3 | 3 | 2 | 2 | |
| Write-off of fully depreciated property and equipment | 0 | 71,000 | 178,000 | 0 | 544,752 | |
| Common stock issuance costs not yet paid | 62,000 | 75,000 | 0 | — | — | |
| Issuance of common stock for conversion of convertible debt | 0 | 1 | 875,000 | 0 | — |