Cardiff Oncology, Inc.
Business
Cardiff Oncology, Inc. develops targeted cancer therapies centered on selective PLK1 inhibition. It primarily develops onvansertib, an oral, highly selective PLK1 small-molecule inhibitor intended for use alone or in combination with standard-of-care chemotherapies and targeted agents. The company’s clinical programs include focused trial programs in RAS-mutated metastatic colorectal cancer, investigator-initiated studies in metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, and triple negative breast cancer, and incorporates biomarker and tumor genomics analyses. Cardiff conducts its operations and clinical activities primarily through U.S.-based trials and third-party manufacturing and distribution partners.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Royalty revenues | 593,000 | 683,000 | 488,000 | 386,000 | 359,000 | |
| Research and development | 35 | 37 | 33 | 27 | 17 | |
| Selling, general and administrative | 14 | 12 | 13 | 13 | 12 | |
| Total operating expenses | 50 | 49 | 46 | 40 | 29 | |
| Loss from operations | −49 | −49 | −45 | −40 | −29 | |
| Interest income | 3 | 3 | 4 | 2 | 264,000 | |
| Other income (expense), net | 5,000 | −39,000 | −98,000 | — | — | |
| Total other income (expense), net | 3 | 3 | 4 | 1 | 564,000 | |
| Net loss | −46 | −45 | −41 | −39 | −28 | |
| Preferred stock dividend payable on Series A Convertible Preferred Stock | −25,000 | −24,000 | −24,000 | −24,000 | −24,000 | |
| Net loss attributable to common stockholders | −46 | −45 | −41 | −39 | −28 | |
| Net loss per common share - basic | −0.69 | −0.95 | −0.93 | −0.89 | −0.73 | |
| Net loss per common share - diluted | −0.69 | −0.95 | −0.93 | −0.89 | −0.73 | |
| Weighted-average shares outstanding - basic | 67 | 48 | 45 | 44 | 39 | |
| Weighted-average shares outstanding - diluted | 67 | 48 | 45 | 44 | 39 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 17 | 51 | 22 | 16 | 12 | |
| Short-term investments | 41 | 40 | 53 | 89 | 129 | |
| Accounts receivable and unbilled receivable | 182,000 | 773,000 | 288,000 | 771,000 | 535,000 | |
| Prepaid expenses and other current assets | 2 | 3 | 2 | — | — | |
| Total current assets | 60 | 95 | 77 | 111 | 146 | |
| Property and equipment, net | 578,000 | 898,000 | 1 | 1 | 382,000 | |
| Operating lease right-of-use assets | 629,000 | 1 | 2 | 2 | 3 | |
| Other assets | 549,000 | 69,000 | 1 | 1 | 239,000 | |
| Total Assets | 62 | 97 | 82 | 116 | 150 | |
| Accounts payable | 8 | 5 | 2 | 2 | 1 | |
| Accrued liabilities | 8 | 8 | 8 | 5 | 5 | |
| Operating lease liabilities | 730,000 | 710,000 | 691,000 | 675,000 | 551,000 | |
| Total current liabilities | 16 | 13 | 10 | 8 | 7 | |
| Operating lease liabilities, net of current portion | 102,000 | 813,000 | 1 | 2 | 3 | |
| Total Liabilities | 16 | 14 | 12 | 10 | 9 | |
| Commitments and contingencies (Note 9) | — | — | — | — | — | |
| Preferred stock, $0.001 par value, 20,000 shares authorized; 277 designated as Series A Convertible Preferred Stock; 61 shares outstanding at December 31, 2025 and December 31, 2024 with liquidation preference of $1,117 and $1,092 at December 31, 2025 and December 31, 2024, respectively | 0 | 0 | 0 | 0 | 1,000 | |
| Common stock, $0.0001 par value, 150,000 shares authorized; 68,305 and 66,524 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 7,000 | 7,000 | 4,000 | 4,000 | 4,000 | |
| Additional paid-in capital | 475 | 467 | 409 | 405 | 401 | |
| Accumulated other comprehensive gain | 50,000 | 34,000 | −67,000 | −395,000 | −142,000 | |
| Accumulated deficit | −430 | −384 | −340 | −298 | −260 | |
| Total stockholders equity | 45 | 83 | 70 | 106 | 140 | |
| Total liabilities and stockholders equity | 62 | 97 | 82 | 116 | 150 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 364,000 | 404,000 | 398,000 | 236,000 | 451,000 | |
| Stock-based compensation expense | 6 | 5 | 5 | 4 | 3 | |
| Amortization of right-of-use assets | 540,000 | 539,000 | — | — | — | |
| Accretion of discounts on short-term investments, net | −848,000 | −598,000 | −921,000 | 632,000 | 2 | |
| Accounts receivable and unbilled receivable | 591,000 | −484,000 | 483,000 | −236,000 | −215,000 | |
| Prepaid expenses and other current assets | 557,000 | −452,000 | 3 | −443,000 | −2 | |
| Other assets | −480,000 | 1 | 108,000 | −1 | 166,000 | |
| Accounts payable and accrued liabilities | 2 | 3 | 3 | 1 | 719,000 | |
| Operating lease liabilities | −691,000 | −626,000 | −566,000 | −404,000 | −811,000 | |
| Net cash used in operating activities | −38 | −38 | −31 | −34 | −23 | |
| Capital expenditures | −44,000 | −80,000 | −582,000 | −1 | −205,000 | |
| Maturities of short-term investments | 71 | 27 | 87 | 76 | 28 | |
| Purchases of short-term investments | −72 | −24 | −70 | −91 | −174 | |
| Sales of short-term investments | 2 | 10 | 20 | 54 | 15 | |
| Net cash provided by investing activities | 1 | 14 | 36 | 38 | −131 | |
| Proceeds from sales of common stock, net of expenses of $0 and $3,286, respectively | 0 | 53 | — | 0 | 34 | |
| Proceeds from exercise of warrants, net of expense of $169 and $0, respectively | 2 | 0 | — | 0 | 1 | |
| Proceeds from exercise of options | 493,000 | 373,000 | 0 | 75,000 | 0 | |
| Net cash provided by financing activities | 3 | 54 | 0 | 75,000 | 35 | |
| Net change in cash and cash equivalents | −34 | 30 | 5 | 4 | −119 | |
| Cash paid for taxes | 1,000 | 1,000 | — | — | — | |
| Purchases of unsettled short-term investments included in accrued liabilities | 744,000 | 0 | 16,000 | 232,000 | 6,000 |