CURIS INC
Business
CURIS INC is a biotechnology company focused on discovery and development of small molecule therapeutics, principally the IRAK4 inhibitor emavusertib. Its main products and programs include emavusertib (clinical development in hematologic malignancies and CNS lymphoma), outlicensed Erivedge and partnered programs such as CA-170 and CA-327, plus other preclinical candidates. The company operates in a single reporting segment centered on drug discovery, clinical development and collaborations, with multiple license and collaboration arrangements (e.g., Aurigene, Genentech). CURIS conducts clinical trials and regulatory interactions across the United States and Europe and relies on third‑party manufacturers, collaborators and global partners for development, commercialization and distribution.
Summary from filing dated 2025-03-31
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenues, net | 9 | 11 | 10 | 10 | 11 | |
| Cost of royalties | 45,000 | 98,000 | 212,000 | 300,000 | 500,000 | |
| Research and development | 28 | 39 | 39 | 43 | 35 | |
| General and administrative | 14 | 17 | 19 | 20 | 17 | |
| Total operating expenses | 42 | 55 | 58 | 63 | 53 | |
| Gain on release of liability related to sale of future royalties associated with sale of assets | 27 | 0 | — | — | — | |
| Loss from operations | −6 | −45 | −48 | −53 | −42 | |
| Interest income | 316,000 | 2 | 3 | 1 | 211,000 | |
| Expense related to the sale of future royalties | −2 | −615,000 | −2 | −5 | −4 | |
| Total other income (expense) | −2 | 1 | 919,000 | −4 | −3 | |
| Net loss | −8 | −43 | −47 | −57 | −45 | |
| Net loss per common share, basic (in dollars per share) | −0.58 | −6.88 | −8.96 | −12.14 | 0.5 | |
| Net loss per common share, diluted (in dollars per share) | −0.58 | −6.88 | −8.96 | −12.14 | 0.5 | |
| Weighted average common shares, basic (in shares) | 13 | 6 | 5 | 5 | 92 | |
| Weighted average common shares, diluted (in shares) | 13 | 6 | 5 | 5 | 92 | |
| Unrealized gain (loss) on marketable securities | 0 | −229,000 | 415,000 | −77,000 | −106,000 | |
| Comprehensive loss | −8 | −44 | −47 | −57 | −46 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 5 | 20 | 27 | 20 | 40 | |
| Accounts receivable | 0 | 3 | 3 | 3 | 3 | |
| Prepaid expenses and other current assets | 2 | 3 | 2 | 4 | 3 | |
| Total current assets | 7 | 26 | 61 | 92 | 122 | |
| Property and equipment, net | 62,000 | 231,000 | 434,000 | 689,000 | 505,000 | |
| Restricted cash, long-term | 544,000 | 544,000 | 544,000 | 635,000 | 726,000 | |
| Operating lease right-of-use asset | 2 | 3 | 3 | 4 | 6 | |
| Other assets | 2 | 2 | 3 | 2 | 0 | |
| Goodwill | 9 | 9 | 9 | 9 | 9 | |
| Total assets | 20 | 41 | 77 | 109 | 162 | |
| Accounts payable | 6 | 3 | 3 | 3 | 6 | |
| Accrued liabilities | 7 | 7 | 9 | 6 | 6 | |
| Current portion of operating lease liability | 1 | 1 | 1 | 1 | 682,000 | |
| Current portion of liability related to sale of future royalties | 0 | 8 | 9 | — | 0 | |
| Total current liabilities | 14 | 19 | 22 | 10 | 13 | |
| Long-term operating lease liability | 428,000 | 2 | 1 | 3 | 4 | |
| Liability related to the sale of future royalties, net | 0 | 27 | 34 | 49 | 54 | |
| Total liabilities | 15 | 47 | 58 | 62 | 72 | |
| Commitments and contingencies, Note 6 | — | — | — | — | — | |
| Preferred stock, $0.01 par value 5,000,000 shares authorized, no shares issued and outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | — | |
| Common stock, $0.01 par value68,343,750 shares authorized, 12,928,853 shares issued and outstanding at December 31, 2025; 34,171,875 shares authorized, 8,487,818 shares issued and outstanding at December 31, 2024 | 129,000 | 85,000 | 59,000 | 48,000 | 916,000 | |
| Additional paid-in capital | 1,253 | 1,234 | 1,216 | 1,196 | 1,182 | |
| Accumulated deficit | −1,200 | −1,240 | −1,196 | −1,149 | −1,092 | |
| Total stockholders equity (deficit) | 5 | −6 | 20 | 47 | 91 | |
| Total liabilities and stockholders equity (deficit) | 20 | 41 | 77 | 109 | 162 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 200,000 | 200,000 | 300,000 | 200,000 | 200,000 | |
| Non-cash lease expense | 1 | 1 | 1 | 1 | 828,000 | |
| Stock-based compensation expense | 4 | 6 | 6 | 7 | 5 | |
| Non-cash activity related to the sale of future royalties prior to the sale of Erivedge | 360,000 | 154,000 | −340,000 | 659,000 | 36,000 | |
| Amortization of premiums and discounts on investments | 0 | −16,000 | −1 | 351,000 | 1 | |
| Accounts receivable | −1 | −555,000 | 181,000 | 249,000 | −181,000 | |
| Prepaid expenses and other assets | 2 | 139,000 | 405,000 | −2 | −2 | |
| Accounts payable and accrued and other liabilities | 3 | −2 | 3 | −4 | 5 | |
| Operating lease liability | −1 | −1 | −1 | −907,000 | −2 | |
| Total adjustments | −20 | 4 | 9 | 2 | 8 | |
| Net cash used in operating activities | −27 | −40 | −38 | −54 | −38 | |
| Purchases of investments | 0 | −18 | −70 | −62 | −93 | |
| Sales and maturities of investments | 0 | 48 | 108 | 95 | 45 | |
| Proceeds from the sale of Erivedge | 3 | 0 | — | — | — | |
| Net cash provided by investing activities | 3 | 29 | 38 | 33 | −48 | |
| Proceeds from issuance of common stock, pre-funded warrants, and common warrants, net of issuance costs | 15 | 12 | 14 | 6 | 0 | |
| Payment of liability of future royalties, net of imputed interest | −6 | −9 | −7 | −5 | −4 | |
| Net cash provided by financing activities | 10 | 3 | 8 | 867,000 | −4 | |
| Net decrease in cash and cash equivalents and restricted cash | −15 | −7 | 7 | −20 | −90 | |
| Issuance costs in accounts payable | 328,000 | 50,000 | 0 | — | 0 | |
| Cash paid for interest | 2 | 461,000 | 2 | 4 | 4 | |
| Increase in right-of-use assets and operating lease liabilities resulting from lease modification | 0 | −1 | 0 | 191,000 | 0 |