Esperion Therapeutics, Inc.
Business
Esperion Therapeutics, Inc. is a commercial-stage biopharmaceutical company developing and commercializing oral, once-daily, non‑statin therapies to address elevated LDL‑C and cardiovascular risk. Its main products are bempedoic acid–based medicines marketed as NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe), with related European brand names NILEMDO and NUSTENDI, and a preclinical pipeline of next‑generation ACLY inhibitors. The company operates commercial, research and development, manufacturing oversight, and licensing/collaboration functions. It sells directly in the United States and distributes internationally through regional collaboration, licensing, supply, and royalty arrangements.
Summary from filing dated 2025-03-07
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total Revenues | 403 | 332 | 116 | 75 | 78 | |
| Cost of goods sold | 129 | 69 | 43 | — | — | |
| Research and development | 48 | 46 | 86 | 119 | 106 | |
| Selling, general and administrative | 166 | 163 | 143 | 109 | 185 | |
| Total operating expenses | 343 | 278 | 272 | 255 | 305 | |
| Income (loss) from operations | 60 | 54 | −156 | −180 | −227 | |
| Interest expense | −85 | −59 | −59 | −57 | — | |
| Loss on extinguishment of debt and exchange transaction | 0 | −55 | 0 | 0 | — | |
| Other income, net | 3 | 8 | 5 | 3 | 4 | |
| Loss before income taxes | −21 | −52 | −209 | — | — | |
| Provision for taxes on income | 2 | 0 | 0 | — | — | |
| Net loss | −23 | −52 | −209 | −234 | −269 | |
| Net loss per common share - basic (in dollars per share) | −0.11 | −0.28 | −2.03 | −3.52 | −9.31 | |
| Net loss per common share - diluted (in dollars per share) | −0.11 | −0.28 | −2.03 | −3.52 | −9.31 | |
| Weighted-average shares outstanding - basic (in shares) | 208 | 187 | 103 | 66 | 29 | |
| Weighted-average shares outstanding - diluted (in shares) | 208 | 187 | 103 | 66 | 29 | |
| Unrealized gain on investments | 0 | 0 | 2,000 | 29,000 | −31,000 | |
| Total comprehensive loss | −23 | −52 | −209 | −234 | −269 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 168 | 145 | 82 | 125 | 209 | |
| Accounts receivable, net | 140 | 80 | 48 | 34 | 23 | |
| Inventories, net | 105 | 94 | 66 | 35 | 34 | |
| Prepaid clinical development costs | 4 | 586,000 | 193,000 | 1 | 1 | |
| Prepaid inventory costs | 41 | 14 | — | — | — | |
| Other prepaid and current assets | 4 | 4 | 5 | 10 | 11 | |
| Total current assets | 463 | 338 | 201 | 247 | 329 | |
| Property and equipment, net | 338,000 | 254,000 | 0 | 164,000 | 664,000 | |
| Right of use operating lease assets | 3 | 6 | 5 | 1 | 2 | |
| Intangible assets | 56,000 | 56,000 | 56,000 | 56,000 | — | |
| Total assets | 466 | 344 | 206 | 248 | 382 | |
| Accounts payable | 65 | 52 | 32 | 23 | 18 | |
| Convertible notes, net of issuance costs | 0 | 55 | 0 | — | — | |
| Accrued clinical development costs | 4 | 5 | 3 | 5 | 7 | |
| Accrued variable consideration | 88 | 57 | 34 | 22 | — | |
| Other accrued liabilities | 19 | 20 | 25 | — | — | |
| Royalty sale liability | 88 | 48 | 0 | — | — | |
| Deferred revenue from collaborations | 34 | 9 | 25 | 4 | 6 | |
| Operating lease liabilities | 2 | 3 | 2 | 384,000 | 1 | |
| Total current liabilities | 301 | 246 | 156 | 92 | 73 | |
| Convertible notes, net of issuance costs | 97 | 97 | 262 | 260 | 258 | |
| Royalty sale liability | 208 | 246 | 0 | — | — | |
| Long-term debt | 152 | 141 | 0 | — | — | |
| Operating lease liabilities | 653,000 | 3 | 3 | 665,000 | 524,000 | |
| Other long-term liabilities | 9 | 0 | — | — | 0 | |
| Total liabilities | 768 | 733 | 661 | 572 | 579 | |
| Commitments and contingencies (Note 5) | — | — | — | — | — | |
| Preferred stock, $0.001 par value; 5,000,000 shares authorized and no shares issued or outstanding as of December 31, 2025 and December 31, 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value; 480,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 247,210,341 shares issued at December 31, 2025 and 197,846,661 shares issued at December 31, 2024 | 245,000 | 196,000 | 118,000 | 75,000 | 61,000 | |
| Additional paid-in capital | 1,376 | 1,267 | 1,149 | 1,071 | 964 | |
| Treasury stock, at cost; 1,994,198 shares at December 31, 2025 and December 31, 2024 | −55 | −55 | −55 | −55 | — | |
| Accumulated other comprehensive loss | 0 | 0 | 0 | −2,000 | −31,000 | |
| Accumulated deficit | −1,624 | −1,601 | −1,549 | −1,340 | −1,106 | |
| Total stockholders' deficit | −302 | −389 | −455 | −324 | −197 | |
| Total liabilities and stockholders' deficit | 466 | 344 | 206 | 248 | 382 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Non-cash royalty revenue | −55 | −26 | 0 | 0 | — | |
| Paid-in-kind interest on long-term debt | 9 | 0 | 0 | — | — | |
| Non-cash interest expense related to the revenue interest liability | 0 | 22 | 47 | 45 | 34 | |
| Non-cash interest expense related to the royalty sale liability | 57 | 25 | 0 | 0 | — | |
| Stock-based compensation expense | 10 | 12 | 12 | 15 | 24 | |
| Depreciation expense | 100,000 | 100,000 | 200,000 | 500,000 | 600,000 | |
| Accretion and amortization of premiums and discounts on investments | 0 | 0 | −412,000 | 279,000 | 12,000 | |
| Amortization of debt issuance costs and discounts | 3 | 1 | 2 | 2 | 2 | |
| Accounts receivable | −60 | −32 | −15 | −11 | −11 | |
| Prepaids and other assets | −31 | −14 | 6 | 1 | 99,000 | |
| Deferred revenue | 26 | −17 | 22 | −3 | 5 | |
| Inventories | −11 | −29 | −30 | −807,000 | −18 | |
| Accounts payable | 21 | 12 | 9 | 6 | — | |
| Other accrued liabilities | 31 | 18 | 22 | 4 | 7 | |
| Other long-term liabilities | 9 | 0 | 0 | 0 | −1 | |
| Net cash used in operating activities | −13 | −24 | −135 | −175 | −264 | |
| Proceeds from sales/maturities of investments | 0 | 0 | 43 | 68 | 0 | |
| Purchases of property and equipment | 0 | −317,000 | 0 | 0 | 0 | |
| Net cash (used in) provided by investing activities | 0 | −317,000 | 43 | 8 | −50 | |
| Proceeds from royalty sale liability | 0 | 305 | 0 | 0 | — | |
| Payment of royalty sale liability issuance costs | 0 | −10 | 0 | 0 | −440,000 | |
| Repurchase or principal payment of revenue interest liability | 0 | −344 | 0 | — | — | |
| Payments on revenue interest liability | 0 | −6 | −16 | −8 | −3 | |
| Proceeds from credit agreement, net of issuance costs | 0 | 145 | 0 | 0 | — | |
| Proceeds from issuance of convertible notes, net of issuance costs | 0 | 100 | 0 | 0 | 0 | |
| Repayment of convertible notes | −55 | −210 | 0 | 0 | — | |
| Proceeds from issuance of common stock, net of issuance costs | 73 | 91 | 52 | 0 | 209 | |
| Proceeds from issuance of common stock from ATM Program, net of issuance costs | 15 | 513,000 | 4 | — | — | |
| Proceeds from exercise of warrants | 10 | 15 | 9 | 0 | — | |
| Payment of issuance costs | −8 | 0 | 0 | — | — | |
| Other financing activities | 244,000 | 29,000 | 21,000 | −219,000 | — | |
| Net cash provided by financing activities | 36 | 86 | 50 | 33 | 268 | |
| Net increase (decrease) in cash and cash equivalents | 23 | 63 | −43 | −134 | −46 | |
| Issuance costs not yet paid | 0 | 8 | 635,000 | 1,000 | — | |
| Purchase of property and equipment not yet paid | 189,000 | 0 | 0 | — | 0 | |
| Non-cash right of use asset | 37,000 | 98,000 | 115,000 | 5,000 | −7,000 | |
| Income taxes paid (refer to Note 17) | 612,000 | 0 | 0 | — | — | |
| Cash paid for interest | 16 | 11 | 11 | — | — |