Guardant Health, Inc.
Business
Guardant Health, Inc. is a precision oncology company that develops and commercializes blood- and tissue-based molecular diagnostic tests and real-world data solutions to inform cancer detection, monitoring and therapy selection. Its main products include Guardant360 CDx and LDT, Guardant Reveal, Guardant360 Response, Guardant360 TissueNext, the Shield screening test, GuardantINFINITY, GuardantOMNI, the GuardantINFORM data platform and GuardantConnect trial-matching services. The company operates clinical diagnostics, biopharmaceutical services and data analytics segments. It distributes tests and services to clinicians, cancer centers and biopharmaceutical customers in the U.S. and internationally via direct sales, partnerships, laboratory collaborations and distributors.
Summary from filing dated 2025-02-20
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 982 | 739 | 564 | 450 | 374 | |
| Cost of revenue | 349 | 290 | 227 | — | — | |
| Research and development expense | 364 | 348 | 367 | 374 | 263 | |
| Sales and marketing expense | 495 | 365 | 295 | 300 | 192 | |
| General and administrative expense | 211 | 180 | 156 | 164 | 207 | |
| Other operating expense | 0 | 0 | 83 | 0 | 0 | |
| Total costs and operating expenses | 1,419 | 1,183 | 1,129 | 994 | 785 | |
| Loss from operations | −437 | −444 | −565 | −544 | −411 | |
| Interest income | 34 | 54 | 35 | 6 | 4 | |
| Interest expense | −4 | −3 | −3 | −3 | — | |
| Other income (expense), net | −10 | −43 | 53 | −13 | 25 | |
| Loss before (benefit from) provision for income taxes | −418 | −435 | −479 | −653 | −384 | |
| (Benefit from) provision for income taxes | −1 | 1 | 685,000 | 1 | 300,000 | |
| Net loss | −416 | −436 | −479 | −655 | — | |
| Net loss per share, basic (in usd per share) | −3.32 | −3.56 | −4.28 | −6.41 | −4 | |
| Net loss per share, diluted (in usd per share) | −3.32 | −3.56 | −4.28 | −6.41 | −4 | |
| Weighted-average shares used in computing net loss per share, basic (in shares) | 125 | 123 | 112 | 102 | 101 | |
| Weighted-average shares used in computing net loss per share, diluted (in shares) | 125 | 123 | 112 | 102 | 101 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 378 | 526 | 1,134 | 142 | 492 | |
| Short-term marketable debt securities | 823 | 314 | 35 | 870 | — | |
| Accounts receivable, net | 138 | 110 | 89 | 97 | 98 | |
| Inventory, net | 86 | 71 | 62 | 52 | 31 | |
| Prepaid expenses and other current assets, net | 41 | 34 | 28 | 32 | 53 | |
| Total current assets | 1,466 | 1,055 | 1,347 | 1,192 | 1,114 | |
| Restricted cash | 111 | 104 | 150,000 | 0 | — | |
| Property and equipment, net | 146 | 137 | 145 | 168 | 124 | |
| Right-of-use assets, net | 159 | 142 | 158 | 174 | 189 | |
| Intangible assets, net | 26 | 7 | 9 | 12 | 14 | |
| Goodwill | 77 | 3 | 3 | 3 | 3 | |
| Other assets, net | 28 | 37 | 124 | 61 | 61 | |
| Total Assets | 2,014 | 1,486 | 1,786 | 1,610 | 2,204 | |
| Accounts payable | 54 | 39 | 52 | — | 18 | |
| Accrued compensation | 120 | 83 | 73 | — | — | |
| Accrued expenses | 78 | 68 | — | — | 45 | |
| Deferred revenue | 51 | 35 | 18 | 17 | — | |
| Total current liabilities | 303 | 226 | 206 | 193 | 195 | |
| Convertible senior notes, net | 1,504 | 1,143 | 1,140 | 1,137 | 1,135 | |
| Long-term operating lease liabilities | 178 | 164 | 186 | 210 | 226 | |
| Other long-term liabilities | 128 | 93 | 96 | 9 | 4 | |
| Total Liabilities | 2,113 | 1,625 | 1,628 | 1,550 | 1,559 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, par value of $0.00001 per share; 10,000,000 shares authorized, no shares issued and outstanding as of December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, par value of $0.00001 per share; 350,000,000 shares authorized as of December 31, 2025 and 2024; 130,635,301 and 123,994,006 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 1,000 | 1,000 | 1,000 | 1,000 | 1,000 | |
| Additional paid-in capital | 2,900 | 2,444 | 2,304 | 1,742 | 1,658 | |
| Accumulated other comprehensive loss | −5 | −5 | −4 | −20 | −5 | |
| Accumulated deficit | −2,995 | −2,578 | −2,142 | −1,662 | −1,008 | |
| Total Stockholders Deficit | −99 | −140 | 159 | 60 | 645 | |
| Total Liabilities and Stockholders Deficit | 2,014 | 1,486 | 1,786 | 1,610 | 2,204 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 40 | 42 | 43 | 36 | 22 | |
| Operating lease costs | 34 | 31 | 30 | 29 | 25 | |
| Gain on extinguishment of convertible notes | −14 | 0 | 0 | — | — | |
| Stock-based compensation | 166 | 140 | 91 | 95 | 151 | |
| Interest income received on marketable debt securities | 8 | 0 | 0 | — | — | |
| Amortization of discount on marketable debt securities | −6 | −7 | −14 | 5 | 13 | |
| Unrealized and realized losses (gains) on marketable equity securities | 0 | 44 | −80 | 8 | — | |
| Impairment of non-marketable equity securities and other related assets | 19 | 0 | 29 | 5 | 0 | |
| Other | −294,000 | 6 | 2 | 21,000 | 47,000 | |
| Accounts receivable, net | −28 | −21 | 8 | 375,000 | −44 | |
| Inventory, net | −15 | −9 | −10 | −21 | −8 | |
| Prepaid expenses and other current assets, net | −6 | −8 | −4 | 20 | −36 | |
| Other assets, net | 212,000 | −2 | 1 | 12 | −4 | |
| Accounts payable and accrued liabilities | 53 | −3 | 5 | 60 | 35 | |
| Other legal liabilities | 0 | 0 | 83 | 0 | — | |
| Operating lease liabilities | −38 | −36 | −31 | −20 | 14 | |
| Deferred revenue | 19 | 19 | 2 | 10 | 3 | |
| Net cash used in operating activities | −185 | −240 | −325 | −309 | −209 | |
| Purchases of marketable debt securities | −818 | −307 | −630 | −304 | −901 | |
| Maturities of marketable debt securities | 307 | 35 | 1,495 | 555 | 952 | |
| Sales of marketable equity securities and other related assets | 0 | 54 | 2 | 0 | — | |
| Purchases of non-marketable equity securities and other related assets | −9 | −8 | −6 | −24 | −39 | |
| Purchases of property and equipment | −48 | −35 | −20 | −77 | −75 | |
| Acquisition of business, net of cash acquired | −59 | 0 | 0 | — | 0 | |
| Net cash (used in) provided by investing activities | −627 | −261 | 840 | 150 | −63 | |
| Proceeds from issuance of common stock under employee stock purchase plan | 14 | 12 | 10 | 9 | 10 | |
| Proceeds from issuance of common stock upon exercise of stock options | 19 | 3 | 405,000 | 3 | 8 | |
| Employee taxes paid related to net share settlement of restricted stock units | −31 | −16 | −11 | −8 | −84 | |
| Repurchase of treasury stock | −45 | 0 | 0 | — | — | |
| Proceeds from reissuance of treasury stock | 88 | 0 | 0 | — | — | |
| Proceeds from equity offerings | 257 | 0 | 493 | 0 | 0 | |
| Payment of equity offering costs | −18 | 0 | −21 | 0 | 0 | |
| Proceeds from borrowings on convertible senior notes | 403 | 0 | 0 | 0 | 0 | |
| Payment of debt issuance costs | −25 | 0 | 0 | 0 | −784,000 | |
| Proceeds from unwinding of convertible note hedges | 5 | 0 | 0 | — | — | |
| Other | 4 | −153,000 | 6 | −1 | −930,000 | |
| Net cash provided by (used in) financing activities | 671 | −996,000 | 477 | −189 | −67 | |
| Net effect of foreign exchange rate changes on cash, cash equivalents and restricted cash | 491,000 | −2 | −911,000 | −2 | −2 | |
| Net (decrease) increase in cash, cash equivalents and restricted cash | −140 | −504 | 992 | −350 | −341 | |
| Cash paid for interest | 4 | 0 | 0 | — | 0 | |
| Cash paid for income taxes | 869,000 | 1 | 2 | 1 | 393,000 | |
| Operating lease liabilities arising from obtaining right-of-use assets | 41 | 8 | 5 | 4 | 171 | |
| Purchases of property and equipment included in accounts payable and accrued liabilities | 4 | 4 | 5 | 8 | 9 |