INOVIO PHARMACEUTICALS, INC.
Business
INOVIO PHARMACEUTICALS, INC. is a clinical-stage biotechnology company developing DNA medicines and proprietary electroporation delivery devices to treat and prevent HPV-associated diseases, cancer and infectious diseases. It offers optimized DNA plasmid therapeutics, DNA-encoded monoclonal antibodies and the CELLECTRA® electroporation devices that facilitate cellular uptake of plasmids for intramuscular or intradermal administration. Its business is organized around product development programs in oncology (e.g., GBM, OPSCC), HPV-related diseases (e.g., RRP) and infectious-disease vaccines and DPROT/DMAb platforms, alongside device manufacturing and collaborative alliances. INOVIO conducts global clinical trials, relies on third-party manufacturers, pursues regulatory approvals, and seeks commercialization through direct efforts and partner licensing in the United States, Europe and other international markets.
Summary from filing dated 2025-03-18
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue from collaborative arrangement | 65,343 | 217,756 | 832,010 | 10 | 2 | |
| Research and development | 54 | 76 | 87 | 188 | 249 | |
| General and administrative | 33 | 37 | 48 | 90 | 54 | |
| Total operating expenses | 87 | 113 | 145 | 278 | 303 | |
| Loss from operations | −87 | −112 | −144 | −268 | −301 | |
| Interest income | 2 | 5 | 8 | — | — | |
| Interest expense | 0 | −177,833 | −1 | — | — | |
| Change in fair value of common stock warrant liabilities | 493,231 | 3 | 0 | — | — | |
| Gain (loss) on investment in affiliated entity | 489,844 | −1 | 773,145 | −2 | −553,570 | |
| Net unrealized gain on available-for-sale equity securities | 1 | 2 | 6 | −8 | −3 | |
| Other expense, net | −3 | −3 | −5 | −4 | 343,371 | |
| Net loss | −85 | −107 | −135 | −280 | −304 | |
| Basic (in USD per share) | −1.81 | −3.95 | −6.09 | −14.07 | −17.45 | |
| Diluted (in USD per share) | −1.81 | −3.95 | −6.09 | −14.07 | −17.45 | |
| Basic (in shares) | 47 | 27 | 22 | 20 | 17 | |
| Diluted (in shares) | 47 | 27 | 22 | 20 | 17 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 44 | 66 | 14 | 46 | 71 | |
| Short-term investments | 14 | 28 | 131 | 207 | 330 | |
| Prepaid expenses and other current assets, including from affiliated entity | 3 | 4 | 5 | 50 | 39 | |
| Total current assets | 61 | 98 | 153 | 315 | 448 | |
| Fixed assets, net | 3 | 4 | 5 | 8 | 17 | |
| Investments in affiliated entity | 2 | 2 | 3 | 2 | 4 | |
| Operating lease right-of-use assets | 7 | 8 | 9 | 10 | 12 | |
| Other assets | 2 | 2 | 605,315 | 684,044 | 1 | |
| Total assets | 74 | 113 | 171 | 349 | 496 | |
| Accrued clinical trial expenses | 650,680 | 2 | 2 | 11 | 10 | |
| Common stock warrant liabilities | 29 | 13 | 0 | — | — | |
| Operating lease liability | 3 | 2 | 2 | 3 | 3 | |
| Total current liabilities | 44 | 35 | 43 | 97 | 66 | |
| Operating lease liability, net of current portion | 7 | 9 | 11 | 13 | 15 | |
| Total liabilities | 50 | 45 | 54 | 126 | 96 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stockpar value $0.001; Authorized shares: 10,000,000, issued and outstanding shares: 9 at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stockpar value $0.001; Authorized shares: 600,000,000 at December 31, 2024 and 2023, issued and outstanding: 36,099,991 at December 31, 2024 and 22,793,075 at December 31, 2023 | 68,997 | 36,099 | 22,792 | 21,090 | 217,382 | |
| Additional paid-in capital | 1,840 | 1,799 | 1,741 | 1,711 | 1,610 | |
| Accumulated deficit | −1,800 | −1,730 | −1,623 | −1,488 | −1,210 | |
| Accumulated other comprehensive loss | −637,963 | −675,667 | −662,601 | −698,741 | −282,236 | |
| Total Inovio Pharmaceuticals, Inc. stockholders equity | 24 | 69 | 117 | 222 | 400 | |
| Total liabilities and stockholders equity | 74 | 113 | 171 | 349 | 496 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 1 | 2 | 3 | 4 | 3 | |
| Amortization of operating lease right-of-use assets | 2 | 1 | 736,472 | 1 | 1 | |
| Non-cash stock-based compensation | 4 | 7 | 11 | 23 | 26 | |
| Non-cash interest on senior convertible notes | 0 | −355,654 | 155,814 | 186,977 | 858,644 | |
| Amortization of discounts on investments | −2,399 | −2 | −5 | −1 | 2 | |
| Loss on sales of short-term investments | 890,916 | 2 | 5 | 4 | 5,397 | |
| Net gain on disposal of fixed assets | 0 | −22,466 | 317,997 | 1 | 0 | |
| Prepaid expenses and other current assets, including from affiliated entity | 1 | 3 | 39 | −5 | −6 | |
| Other assets | −32,821 | 38,900 | 78,729 | 741,750 | 25 | |
| Accounts payable and accrued expenses, including due to affiliated entity | −6 | −3 | −46 | 33 | 26 | |
| Accrued clinical trial expenses | −1 | −343,522 | −8 | 267,807 | 375,921 | |
| Operating lease right-of-use assets and liabilities, net | −2 | −2 | −2 | −3 | −2 | |
| Net cash used in operating activities | −89 | −104 | −124 | −216 | −216 | |
| Purchases of investments | −5 | −54 | −203 | −249 | −349 | |
| Proceeds from sale of investments | 14 | 28 | 285 | 361 | 175 | |
| Proceeds from maturity of investments | 5 | 131 | — | — | — | |
| Purchases of capital assets | −285,698 | −487,832 | −320,898 | −969,153 | −1 | |
| Proceeds from sale of capital assets | 0 | 59,319 | 6 | 0 | 0 | |
| Net cash provided by investing activities | 14 | 104 | 87 | 110 | −175 | |
| Repayment of convertible senior notes | 0 | −16 | 0 | — | — | |
| Proceeds from issuance of common stock, net of issuance costs | 35 | 36 | 5 | 83 | 209 | |
| Proceeds from warrant exercises | 1 | 0 | — | — | — | |
| Proceeds from stock option exercises | 1,000 | 68,000 | 0 | — | — | |
| Taxes paid related to net share settlement of equity awards | −110,783 | −420,795 | −466,646 | −1 | −5 | |
| Net cash provided by financing activities | 53 | 51 | 5 | 82 | 211 | |
| Effect of exchange rate changes on cash and cash equivalents | 0 | 32,403 | −3,920 | −25,556 | −30,134 | |
| (Decrease) Increase in cash and cash equivalents | −22 | 52 | −32 | −25 | −180 | |
| Interest paid | 0 | 533,487 | 1 | 1 | 1 |