Jasper Therapeutics, Inc.
Business
Jasper Therapeutics, Inc. is a clinical-stage biotechnology company developing therapeutics that target mast cell–driven diseases and therapies for hematopoietic stem cell conditioning. Its principal product candidate, briquilimab, is a humanized anti–c-Kit monoclonal antibody being developed to deplete mast cells for conditions such as chronic spontaneous and inducible urticarias and allergic asthma, and as a conditioning agent for stem cell transplant in SCID. Business is organized around clinical development programs (Phase 1b/2a studies, open-label extensions and a Phase 1/2 SCID trial) and in-licensed intellectual property and manufacturing collaborations. Jasper conducts clinical trials primarily in the United States and plans regulatory and commercial activities in North America, Europe and Japan, while leveraging strategic partnerships for manufacturing and international commercialization.
Summary from filing dated 2025-02-28
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 63 | 56 | 52 | 35 | 25 | |
| General and administrative | 21 | 20 | 17 | 17 | 11 | |
| Total operating expenses | 84 | 76 | 69 | 51 | 37 | |
| Loss from operations | −84 | −76 | −69 | −51 | −37 | |
| Interest income | 2 | 5 | 5 | 701,000 | — | |
| Change in fair value of warrant liability | 9 | — | −575,000 | 7 | 500,000 | |
| Other expense, net | −2 | −88,000 | −246,000 | 586,000 | −80,000 | |
| Total other income, net | 8 | 5 | 4 | — | — | |
| Net loss and comprehensive loss | −76 | −71 | −65 | −38 | −31 | |
| Net loss per share attributable to common stockholders, basic (in Dollars per share) | −3.95 | −4.89 | −6.18 | −10.33 | −2.69 | |
| Net loss per share attributable to common stockholders, diluted (in Dollars per share) | −3.95 | −4.89 | −6.18 | −10.33 | −2.69 | |
| Weighted-average shares used in computing net loss per share attributable to common stockholders, basic (in Shares) | 19 | 15 | 10 | 4 | 11 | |
| Weighted-average shares used in computing net loss per share attributable to common stockholders, diluted (in Shares) | 19 | 15 | 10 | 4 | 11 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 29 | 72 | 87 | 38 | 85 | |
| Prepaid expenses and other current assets | 6 | 4 | 2 | 3 | 3 | |
| Total current assets | 35 | 76 | 89 | 42 | 88 | |
| Property and equipment, net | 102,000 | 2 | 3 | 4 | 4 | |
| Operating lease right-of-use assets | 502,000 | 976,000 | 1 | 2 | 1 | |
| Restricted cash | 417,000 | 417,000 | 417,000 | 417,000 | 345,000 | |
| Other non-current assets | 113,000 | 820,000 | 1 | 759,000 | 645,000 | |
| Total assets | 36 | 80 | 95 | 48 | 94 | |
| Accounts payable | 6 | 4 | 4 | 2 | 4 | |
| Current portion of operating lease liabilities | 1 | 1 | 972,000 | 865,000 | 505,000 | |
| Accrued expenses and other current liabilities | 6 | 10 | 7 | 4 | 4 | |
| Total current liabilities | 13 | 15 | 12 | 7 | 8 | |
| Non-current portion of operating lease liabilities | — | 724,000 | 2 | 3 | 2 | |
| Warrant liability | 16 | — | — | 150,000 | — | |
| Other non-current liabilities | 2 | 2 | 2 | 2 | 643,000 | |
| Total liabilities | 32 | 18 | 16 | 12 | 24 | |
| Commitments and contingencies (Note 8) | — | — | — | — | — | |
| Preferred stock: $0.0001 par value 10,000,000 shares authorized at December 31, 2025 and 2024; none issued and outstanding at December 31, 2025 and 2024 | — | — | — | — | — | |
| Common stock: $0.0001 par value 492,000,000 shares authorized at December 31, 2025 and 2024; 27,996,819 and 15,022,122 shares issued and outstanding at December 31, 2025 and 2024, respectively | 3,000 | 2,000 | 1,000 | — | 4,000 | |
| Additional paid-in capital | 321 | 303 | 248 | 141 | 137 | |
| Accumulated deficit | −317 | −241 | −170 | −105 | −67 | |
| Total stockholders equity | 4 | 62 | 78 | 36 | 70 | |
| Total liabilities and stockholders equity | 36 | 80 | 95 | 48 | 94 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization expense | 1 | 1 | 1 | 975,000 | 377,000 | |
| Impairment of long-lived assets | 1 | — | — | — | — | |
| Non-cash lease expense | 1 | 491,000 | 419,000 | — | — | |
| Stock-based compensation expense | 7 | 7 | 5 | 4 | 1 | |
| Offering costs recognized in other expense, net | 2 | — | — | — | — | |
| Prepaid expenses and other current assets | −2 | −2 | 767,000 | 312,000 | −2 | |
| Other non-current assets | 707,000 | 523,000 | −584,000 | −114,000 | −347,000 | |
| Accounts payable | 2 | −122,000 | 2 | −2 | 3 | |
| Accrued expenses and other current liabilities | −4 | 3 | 3 | 836,000 | 959,000 | |
| Operating lease liability | −2 | −973,000 | −865,000 | −589,000 | −117,000 | |
| Net cash used in operating activities | −77 | −63 | −52 | −46 | −34 | |
| Purchases of property and equipment | −7,000 | −552,000 | −267,000 | −576,000 | −2 | |
| Proceeds from sales of property and equipment | 12,000 | 20,000 | — | — | — | |
| Net cash provided by (used in) investing activities | 5,000 | −532,000 | −267,000 | −576,000 | −2 | |
| Proceeds from issuance of common stock through ATM offering, net | 6 | — | 101 | 28,000 | — | |
| Proceeds from issuance of common stock and warrants through underwritten offering, net | 28 | 47 | — | — | — | |
| Proceeds from exercise of common stock options | — | 329,000 | 388,000 | 27,000 | 235,000 | |
| Proceeds from issuance of common stock pursuant to Employee Stock Purchase Plan | 243,000 | 360,000 | — | — | — | |
| Net cash provided by financing activities | 34 | 48 | 101 | 55,000 | 101 | |
| Net decrease in cash, cash equivalents and restricted cash | −43 | −15 | 49 | −46 | 65 | |
| Right-of-use asset obtained in exchange for lease liabilities | 1 | — | — | 1 | — | |
| Warrant liability recognized in connection with underwritten offering | 25 | — | — | — | — |