KalVista Pharmaceuticals, Inc.
Business
KalVista Pharmaceuticals, Inc. is a global biopharmaceutical company that develops and delivers orally administered therapies for rare diseases, with a primary focus on hereditary angioedema (HAE). Its main product is EKTERLY (sebetralstat), an oral plasma kallikrein inhibitor approved for on‑demand treatment of acute HAE attacks, and the company maintains clinical programs including pediatric and long‑term safety studies as well as preclinical Factor XIIa inhibitor efforts. KalVista operates research and development, clinical development, regulatory, and commercial functions and pursues licensing and partnership arrangements. It commercializes in the United States and pursues regulatory approvals and partner‑led distribution across Europe, Japan, the U.K., Canada and other international markets.
Summary from filing dated 2025-07-10
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-04-30 | FY 2024 2024-04-30 | FY 2023 2023-04-30 | FY 2022 2022-04-30 | FY 2021 2021-04-30 |
|---|---|---|---|---|---|---|
| Research and development | 72 | 86 | 80 | 70 | 41 | |
| General and administrative | 116 | 54 | 31 | 26 | 17 | |
| Total operating expenses | 188 | 140 | 111 | 97 | 58 | |
| Operating loss | −188 | −140 | −111 | −97 | −58 | |
| Interest income | 6 | 4 | 2 | 1 | 903,000 | |
| Interest (expense) | −6 | — | — | — | — | |
| Foreign currency exchange gain (loss) | 2 | 138,000 | 90,000 | −2 | −847,000 | |
| Other income (expenses), net | 5 | 10 | 16 | 15 | 10 | |
| Total other income | 8 | 14 | 18 | 14 | 12 | |
| Loss before income taxes | −180 | −127 | −93 | −82 | −82 | |
| Income tax (benefit) expense | 3 | 0 | 0 | 0 | 0 | |
| Net loss | −183 | −127 | −93 | −82 | −46 | |
| Foreign currency translation loss | −3 | −394,000 | −604,000 | −1 | 1 | |
| Unrealized holding gain on marketable securities | 2 | 1 | 1 | −2 | −473,000 | |
| Reclassification adjustment for realized (gain) loss on available for sale securities included in net loss | −2 | −1 | 139,000 | 581,000 | −153,000 | |
| Total other comprehensive (loss): | −2 | −428,000 | 801,000 | −2 | 450,000 | |
| Comprehensive loss | −185 | −127 | −92 | −85 | −46 | |
| Net loss per share, basic | −3.69 | −3.44 | −3.33 | −3.36 | −2.42 | |
| Net loss per share, diluted | −3.69 | −3.44 | −3.33 | −3.36 | −2.42 | |
| Weighted average common shares outstanding, basic | 50 | 37 | 28 | 24 | 19 | |
| Weighted average common shares outstanding, diluted | 50 | 37 | 28 | 24 | 19 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-04-30 | FY 2024 2024-04-30 | FY 2023 2023-04-30 | FY 2022 2022-04-30 | FY 2021 2021-04-30 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 132 | 32 | 56 | 31 | 51 | |
| Marketable securities | 89 | 179 | 93 | 135 | 198 | |
| Research and development tax credit receivable | 1 | 8 | 17 | 14 | 10 | |
| Prepaid expenses and other current assets | 20 | 7 | 6 | 13 | 5 | |
| Total current assets | 242 | 226 | 172 | 194 | 264 | |
| Property and equipment, net | 2 | 2 | 3 | 2 | 2 | |
| Right of use assets | 6 | 7 | 8 | 8 | 6 | |
| Other assets | 2 | 567,000 | 106,000 | 193,000 | 200,000 | |
| Total assets | 251 | 235 | 183 | 204 | 272 | |
| Accounts payable | 5 | 9 | 5 | 4 | 2 | |
| Accrued expenses | 27 | 12 | 9 | 7 | 7 | |
| Lease liability - current portion | 2 | 1 | 1 | 977,000 | 863,000 | |
| Deferred revenue | 11 | — | — | — | — | |
| Total current liabilities | 45 | 23 | 15 | 12 | 10 | |
| Lease liability - net of current portion | 4 | 6 | 7 | 7 | 5 | |
| Deferred royalty obligation | 106 | — | — | — | — | |
| Total long-term liabilities | 110 | 6 | 7 | 7 | 5 | |
| Commitments and contingencies (Note 9) | — | — | — | — | — | |
| Common stock, $0.001 par value, 100,000,000 authorized Shares issued and outstanding: 49,762,048 and 42,521,975 as of April 30, 2025 and 2024, respectively | 50,000 | 42,000 | 34,000 | 25,000 | 24,000 | |
| Additional paid-in capital | 754 | 680 | 507 | 439 | 426 | |
| Accumulated deficit | −653 | −470 | −343 | −250 | −168 | |
| Accumulated other comprehensive loss | −5 | −3 | −3 | −4 | −1 | |
| Total stockholders equity | 95 | 207 | 161 | 185 | 257 | |
| Total liabilities and stockholders equity | 251 | 235 | 183 | 204 | 272 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-04-30 | FY 2024 2024-04-30 | FY 2023 2023-04-30 | FY 2022 2022-04-30 | FY 2021 2021-04-30 |
|---|---|---|---|---|---|---|
| Net loss | −183 | −127 | −93 | −82 | −46 | |
| Depreciation and amortization | 900,000 | 800,000 | 700,000 | 564,000 | 537,000 | |
| Stock-based compensation expense | 12 | 22 | 10 | 11 | 7 | |
| Realized (gain) loss from sale of marketable securities | −2 | −1 | 139,000 | 581,000 | — | |
| Non-cash operating lease expense | 370,000 | −12,000 | 84,000 | 179,000 | 114,000 | |
| Amortization of premium on available for sale securities | 14,000 | 92,000 | 988,000 | 3 | 685,000 | |
| Foreign currency exchange loss (gain) | −4 | 760,000 | −2 | 2 | −574,000 | |
| Fair value adjustment to derivative liability | 2 | — | — | — | — | |
| Non-cash interest expense and amortization of issuance costs | 6 | — | — | — | — | |
| Research and development tax credit receivable | 7 | 8 | −2 | −5 | 7 | |
| Prepaid expenses and other assets | −1 | −538,000 | 7 | −9 | −244,000 | |
| Other receivables | −11 | — | — | — | — | |
| Accounts payable | −5 | 4 | 1 | 2 | 150,000 | |
| Accrued expenses | 14 | 3 | 2 | 472,000 | 983,000 | |
| Deferred revenue | 11 | — | — | — | — | |
| Net cash used in operating activities | −153 | −89 | −75 | −78 | −30 | |
| Purchases of available for sale securities | −31 | −189 | −98 | −137 | −201 | |
| Sales and maturities of available for sale securities | 123 | 105 | 141 | 196 | 54 | |
| Acquisition of property and equipment | −434,000 | −42,000 | −1 | −931,000 | −82,000 | |
| Capitalized website development costs | −495,000 | −401,000 | — | — | — | |
| Net cash provided by investing activities | 91 | −85 | 41 | 58 | −148 | |
| Proceeds from the royalty agreement | 100 | — | — | — | — | |
| Issuance costs associated with the royalty agreement | −2 | — | — | — | — | |
| Issuance of common stock, net of offering expenses | 56 | 97 | 57 | — | 211 | |
| Issuance of pre-funded warrants | — | 53 | 1 | — | — | |
| Issuance of common stock from equity incentive plans | 6 | 646,000 | 449,000 | 2 | 2 | |
| Net cash provided by financing activities | 160 | 151 | 58 | 2 | 212 | |
| Effect of exchange rate changes on cash and cash equivalents | 3 | −1 | 1 | −1 | 511,000 | |
| Net increase (decrease) in cash and cash equivalents | 100 | −24 | 26 | −20 | 35 | |
| Right of use assets obtained in exchange for operating lease liabilities | 725,000 | 162,000 | 1 | 3 | 5 | |
| Website development costs included in accounts payable | — | 31,000 | — | — | — |