Lineage Cell Therapeutics, Inc.
Business
Lineage Cell Therapeutics, Inc. is a clinical-stage biotechnology company developing allogeneic (off-the-shelf) cell therapies for serious neurological and ophthalmic conditions. It designs, develops, manufactures and tests specialized human cells derived from pluripotent cell lines, including retinal pigment epithelial cells, oligodendrocyte progenitor cells, auditory neuron progenitors, photoreceptors and other engineered or hypoimmune lines. Its operations include research and preclinical programs, clinical-stage transplant programs, manufacturing and process development performed through its internal cGMP capabilities and majority-owned subsidiary. Lineage distributes investigational products to clinical sites and collaborates with pharmaceutical partners and research institutions for clinical development and services.
Summary from filing dated 2025-03-10
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 15 | 9 | 9 | 15 | — | |
| Cost of royalties | 146,000 | 334,000 | — | — | — | |
| Research and development | 18 | 12 | 16 | 14 | 34 | |
| General and administrative | 18 | 18 | 17 | 23 | 18 | |
| Loss on impairment of intangible asset (Note 6 and Note 13) | 15 | 0 | — | — | — | |
| Total operating expenses | 51 | 31 | 34 | — | — | |
| Loss from operations | −37 | −21 | −25 | −23 | −49 | |
| Interest income, net | 2 | 2 | 2 | 829,000 | — | |
| Loss on marketable equity securities, net | −8,000 | −8,000 | −176,000 | −2 | — | |
| Change in fair value of warrant liability | −36 | 2 | 0 | 225,000 | — | |
| Foreign currency transaction gain (loss), net | 2 | −269,000 | −544,000 | — | — | |
| Other income (expense), net | −132,000 | −670,000 | 542,000 | −2 | 1 | |
| Total other income (expenses) | −32 | 3 | 1 | −3 | 6 | |
| LOSS BEFORE INCOME TAXES | −69 | −19 | −23 | −26 | −43 | |
| Income tax benefit | 5 | 0 | 2 | −500,000 | — | |
| NET LOSS | −63 | −19 | −21 | −26 | −43 | |
| Net (income) loss attributable to noncontrolling interest | −166,000 | −27,000 | −7,000 | 80,000 | 251,000 | |
| NET LOSS ATTRIBUTABLE TO LINEAGE | −64 | −19 | −21 | −26 | −43 | |
| Net loss per common share attributable to Lineage basic | −0.28 | −0.09 | −0.12 | −0.15 | −0.26 | |
| Net loss per common share attributable to Lineage diluted | −0.28 | −0.09 | −0.12 | −0.15 | — | |
| Weighted-average common shares used to compute net loss per common share, basic | 230 | 200 | 173 | 170 | 165 | |
| Weighted-average common shares used to compute net loss per common share, diluted | 230 | 200 | 173 | 170 | — |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 41 | 46 | 35 | 11 | 56 | |
| Marketable securities | 15 | 2 | 50,000 | 47 | 3 | |
| Accounts receivable | 891,000 | 638,000 | 700,000 | 300,000 | — | |
| Prepaid expenses and other current assets | 2 | 3 | 2 | 2 | 2 | |
| Total current assets | 59 | 51 | 38 | 60 | 112 | |
| Property and equipment, net | 3 | 2 | 2 | 6 | 5 | |
| Operating lease right-of-use assets | 2 | 2 | 3 | — | — | |
| Deposits and other long-term assets | 558,000 | 614,000 | 577,000 | 627,000 | — | |
| Goodwill | 11 | 11 | 11 | 11 | 11 | |
| Intangible assets, net | 32 | 47 | 47 | 47 | 47 | |
| Deferred tax asset, net | 6 | 0 | — | — | — | |
| TOTAL ASSETS | 113 | 113 | 101 | 124 | 175 | |
| Accounts payable and accrued liabilities | 7 | 5 | 6 | 9 | 28 | |
| Operating lease liabilities, current portion | 816,000 | 1 | 830,000 | 916,000 | 801,000 | |
| Finance lease liabilities, current portion | 37,000 | 55,000 | 52,000 | 36,000 | 30,000 | |
| Deferred revenues, current portion | 3 | 7 | 11 | 9 | 18 | |
| Total current liabilities | 11 | 14 | 18 | 19 | 47 | |
| Deferred tax liability, net | 22,000 | 273,000 | 273,000 | 2 | 2 | |
| Deferred revenues, net of current portion | 12 | 14 | 19 | 28 | 32 | |
| Operating lease liabilities, net of current portion | 2 | 1 | 2 | 3 | 2 | |
| Finance lease liabilities, net of current portion | 32,000 | 67,000 | 91,000 | 84,000 | 30,000 | |
| Warrant liabilities | 44 | 6 | 0 | — | — | |
| TOTAL LIABILITIES | 69 | 36 | 39 | 52 | 84 | |
| Commitments and contingencies (Note 13) | — | — | — | — | — | |
| Preferred shares, no par value, 2,000 shares authorized; none issued and outstanding as of December 31, 2025 and 2024 | — | — | — | — | — | |
| Common shares, no par value, 450,000 shares authorized as of December 31, 2025 and 2024; 243,122 and 220,416 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 515 | 485 | 451 | 440 | 435 | |
| Accumulated other comprehensive loss | −4 | −3 | −3 | −4 | −5 | |
| Accumulated deficit | −467 | −403 | −385 | −363 | −337 | |
| Lineage's shareholders' equity | 45 | 78 | 63 | 73 | 92 | |
| Noncontrolling deficit | −1 | −1 | −1 | −1 | −1 | |
| Total shareholders equity | 43 | 77 | 62 | 72 | 91 | |
| TOTAL LIABILITIES AND SHAREHOLDERS EQUITY | 113 | 113 | 101 | 124 | 175 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Issuance costs for common stock warrant liabilities | 183,000 | 688,000 | 0 | — | — | |
| Accretion of income on marketable debt securities | −44,000 | −229,000 | −679,000 | −501,000 | — | |
| Depreciation and amortization expense | 699,000 | 587,000 | 562,000 | 582,000 | — | |
| Change in right-of-use assets and liabilities | −58,000 | −42,000 | 91,000 | −35,000 | 14,000 | |
| Amortization of intangible assets | 0 | 22,000 | 130,000 | 100,000 | 210,000 | |
| Stock-based compensation | 5 | 5 | 5 | 4 | 4 | |
| Deferred income tax benefit | −5 | 0 | −2 | 0 | — | |
| Foreign currency remeasurement | −2 | 273,000 | — | — | — | |
| Accounts receivable | −316,000 | 106,000 | −446,000 | 50 | −857,000 | |
| Prepaid expenses and other current assets | 46,000 | 489,000 | −418,000 | 446,000 | −72,000 | |
| Accounts payable and accrued liabilities | 2 | −2 | −2 | −19 | 22 | |
| Deferred revenue | −6 | −8 | −8 | −13 | — | |
| Net cash used in operating activities | −19 | −23 | −29 | 1 | −24 | |
| Proceeds from the sale of marketable equity securities | 0 | 18,000 | 196,000 | 0 | — | |
| Purchases of marketable debt securities | −15 | −9 | −16 | −53 | — | |
| Maturities of marketable debt securities | 2 | 7 | 63 | 8 | — | |
| Purchase of equipment | −522,000 | −565,000 | −674,000 | −413,000 | −340,000 | |
| Net cash used in investing activities | −13 | −2 | 46 | −46 | 10 | |
| Proceeds from employee options exercised | 1 | 229,000 | 88,000 | 648,000 | 7 | |
| Proceeds from exercise of warrants | 319,000 | 0 | 0 | 991,000 | — | |
| Common shares received and retired for employee taxes paid | −16,000 | −23,000 | −37,000 | −17,000 | — | |
| Payment of financed insurance premium | −684,000 | −171,000 | 0 | — | — | |
| Payment of finance lease liabilities | −59,000 | −54,000 | −54,000 | −32,000 | — | |
| Net cash provided by financing activities | 27 | 36 | 6 | 2 | 37 | |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | 396,000 | −95,000 | −250,000 | −873,000 | — | |
| NET DECREASE (INCREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH | −5 | 10 | 24 | −44 | 23 | |
| Cash paid for interest | 29,000 | 9,000 | 10,000 | 13,000 | 13,000 | |
| Financing costs in accounts payable and accrued liabilities | 3,000 | 179,000 | 0 | — | — | |
| Fair value of warrant liability recognized upon issuance in registered direct financing | 2 | 8 | 0 | — | — | |
| Financed insurance premium | 0 | 855,000 | 0 | — | — |