LeonaBio, Inc.
Business
Athira Pharma, Inc. is a clinical‑stage biopharmaceutical company developing small molecules engineered to restore neuronal health and slow neurodegeneration. Its main products include orally available ATH-1105 and ATH-1020 and previously developed fosgonimeton, all designed as ATH positive modulators to enhance the neurotrophic HGF/MET system for indications such as ALS, Alzheimer’s, Parkinson’s and neuropathic pain. The company’s business centers on discovery, preclinical and clinical development, intellectual property management, and partnering/licensing activities. It conducts clinical trials in the United States and internationally and relies on third‑party CDMOs and strategic partners for manufacturing, supply and potential commercialization.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 18 | 71 | 94 | 61 | 43 | |
| Acquired in-process research and development | 68 | — | — | — | — | |
| General and administrative | 17 | 26 | 33 | 33 | 21 | |
| Legal expense | — | 4 | — | 10 | — | |
| Total operating expenses | 102 | 101 | 125 | 104 | 64 | |
| Loss from operations | −102 | −101 | −125 | −104 | −64 | |
| Other income, net | 1 | 4 | 8 | 3 | 334,000 | |
| Sermonix pre-funded warrant change in fair value | −5 | — | — | — | — | |
| Net loss | −106 | −97 | −118 | −96 | −55 | |
| Unrealized (loss) gain on available-for-sale securities | −5,000 | 350,000 | 2 | −2 | −421,000 | |
| Comprehensive loss attributable to common stockholders | −106 | −97 | −116 | −97 | −55 | |
| Net loss per share attributable to common stockholders, basic | −24.7 | −25.19 | −3.09 | −2.53 | −1.49 | |
| Net loss per share attributable to common stockholders, diluted | −24.7 | −25.19 | −3.09 | −2.53 | −1.49 | |
| Weighted-average shares used in computing net loss per share attributable to common stockholders, basic | 4 | 4 | 38 | 38 | 37 | |
| Weighted-average shares used in computing net loss per share attributable to common stockholders, diluted | 4 | 4 | 38 | 38 | 37 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 69 | 48 | 91 | 96 | 111 | |
| Short-term investments | 19 | 3 | 57 | 104 | 143 | |
| Prepaid expenses and other current assets | 1 | 4 | 6 | 6 | 5 | |
| Total current assets | 89 | 55 | 155 | 208 | 261 | |
| Restricted cash | 631,000 | 631,000 | 631,000 | 420,000 | — | |
| Property and equipment, net | 1 | 2 | 3 | 4 | 4 | |
| Operating lease right-of-use asset | 535,000 | 808,000 | 1 | 1 | 1 | |
| Other long-term assets | 55,000 | 55,000 | 448,000 | 55,000 | 56,000 | |
| Total assets | 92 | 59 | 160 | 258 | 332 | |
| Accounts payable | 5 | 319,000 | 129,000 | 3 | 567,000 | |
| Accrued liabilities | 5 | 12 | 18 | 9 | 8 | |
| Sermonix pre-funded warrant | 37 | — | — | — | — | |
| Current operating lease liability | 465,000 | 414,000 | 368,000 | 326,000 | 288,000 | |
| Total current liabilities | 48 | 13 | 29 | 21 | 9 | |
| Operating lease liability, less current portion | 338,000 | 803,000 | 1 | 2 | 2 | |
| Milestone Liabilities | 15 | — | — | — | — | |
| Other long-term liabilities | 1 | — | — | — | — | |
| Total liabilities | 64 | 14 | 30 | 23 | 11 | |
| Common stock, $0.0001 par value; 90,000,000 shares authorized at December 31, 2025 and December 31, 2024, respectively; 9,335,913 and 3,904,049 shares issued and outstanding at December 31,2025 and December 31,2024, respectively | 1,000 | 0 | 4,000 | 4,000 | 4,000 | |
| Additional paid-in capital | 540 | 451 | 440 | 429 | 417 | |
| Accumulated other comprehensive (loss) income | −4,000 | 1,000 | −349,000 | −2 | −388,000 | |
| Accumulated deficit | −512 | −406 | −309 | −192 | −96 | |
| Total stockholders' equity | 28 | 45 | 130 | 235 | 321 | |
| Total liabilities and stockholders' equity | 92 | 59 | 160 | 258 | 332 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −106 | −97 | −118 | −96 | −55 | |
| Non-cash consideration for acquired in-process research and development | 68 | — | — | — | — | |
| Stock-based compensation | 6 | 11 | 11 | 11 | 5 | |
| Depreciation expense | 1 | 1 | 969,000 | 845,000 | 479,000 | |
| Non-cash lease expense | 273,000 | 241,000 | 214,000 | 203,000 | 155,000 | |
| Amortization of premiums and accretion of discounts on available-for-sale securities, net | −329,000 | −515,000 | −1 | −422,000 | 493,000 | |
| Loss on disposal of equipment | — | 7,000 | — | — | — | |
| Prepaid expenses and other current and long-term assets, net | 2 | 3 | −113,000 | −1 | 2 | |
| Insurance recovery receivable related to legal settlement | — | 2 | −2 | — | — | |
| Accounts payable and accrued liabilities | −21 | −6 | 7 | 2 | 5 | |
| Accrued legal settlement | — | −10 | — | 10 | — | |
| Operating lease liability | −414,000 | −368,000 | −326,000 | −15,000 | 241,000 | |
| Other long-term liabilities | −59,000 | — | — | — | — | |
| Net cash used in operating activities | −46 | −97 | −101 | −72 | −43 | |
| Purchases of available-for-sale securities | −38 | −14 | −28 | −95 | −299 | |
| Maturities of available-for-sale securities | 22 | 69 | 123 | 154 | 279 | |
| Purchases of property and equipment | — | −33,000 | −304,000 | −1 | −2 | |
| Net cash (used in) provided by investing activities | −16 | 55 | 95 | 58 | −4 | |
| Proceeds from exercise of common stock options and issuance of common stock under employee stock purchase plan. | 37,000 | 194,000 | 493,000 | 654,000 | — | |
| Proceeds from PIPE financing | 90 | — | — | — | — | |
| Issuance costs from PIPE financing | −8 | — | — | — | — | |
| Net cash provided by financing activities | 82 | 194,000 | 493,000 | 654,000 | 97 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 21 | −42 | −5 | −14 | 50 |