Seres Therapeutics, Inc.
Business
Seres Therapeutics is a clinical-stage biopharmaceutical company developing live biotherapeutic products (LBPs)—defined consortia of bacteria designed to modulate the human microbiome and treat diseases. The company successfully developed and sold VOWST, the first FDA-approved oral microbiome therapeutic, to Nestlé Health Science in September 2024. Seres' pipeline includes SER-155 for infectious disease and immune-related conditions, SER-603 for inflammatory bowel disease, and SER-147 for chronic liver disease, supported by proprietary discovery platforms, manufacturing capabilities, and clinical development networks.
Summary from 10-K filed 2026-03-12
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Grant revenue | 789,000 | 0 | 0 | 0 | 1 | |
| Total revenue | 789,000 | 0 | 0 | 7 | 145 | |
| Research and development expenses | 49 | 65 | 118 | 110 | 142 | |
| General and administrative expenses | 39 | 53 | 78 | 70 | 69 | |
| Manufacturing services | 7 | 4 | 0 | 0 | — | |
| Total operating expenses | 95 | 121 | 195 | 180 | 209 | |
| Loss from operations | −94 | −121 | −195 | −180 | −64 | |
| Gain on sale of VOWST Business | 81 | 6 | 0 | 0 | — | |
| Interest income | 2 | 4 | 7 | 3 | 3 | |
| Interest expense | 0 | 0 | −2 | −6 | −3 | |
| Other income (expense), net | 17 | −14 | 134,000 | −705,000 | −1 | |
| Total other income (expense), net | 100 | −4 | 5 | −4 | −1 | |
| Net income (loss) from continuing operations | 6 | −126 | −190 | −184 | — | |
| Net income from discontinued operations, net of tax | 0 | 126 | 76 | −67 | — | |
| Net income (loss) | 6 | 136,000 | −114 | −250 | −66 | |
| Net income (loss) from continuing operations per share attributable to common stockholders - basic | 0.64 | −16.2 | −29.71 | −1.7 | — | |
| Net income from discontinued operations per share attributable to common stockholders - basic | 0 | 16.2 | 11.94 | −0.62 | — | |
| Net income (loss) per share attributable to common stockholders - basic | 0.64 | 0 | −17.77 | −2.31 | −0.72 | |
| Net income (loss) from continuing operations per share attributable to common stockholders - diluted | 0.64 | −16.2 | −29.71 | −1.7 | — | |
| Net income from discontinued operations per share attributable to common stockholders - diluted | 0 | 16.2 | 11.94 | −0.62 | — | |
| Net income (loss) per share attributable to common stockholders - diluted | 0.64 | 0 | −17.77 | −2.31 | −0.72 | |
| Weighted average common shares outstanding - basic | 9 | 8 | 6 | 108 | 92 | |
| Weighted average common shares outstanding - diluted | 9 | 8 | 6 | 108 | 92 | |
| Unrealized gain on investments, net of tax of $0 | 0 | 0 | 10,000 | 49,000 | −12,000 | |
| Currency translation adjustment | 0 | 0 | 2,000 | −1,000 | −1,000 | |
| Total other comprehensive income | 0 | 0 | 12,000 | 48,000 | −13,000 | |
| Comprehensive income (loss) | 6 | 136,000 | −114 | −250 | −66 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 46 | 31 | 128 | 163 | 180 | |
| Accounts receivable due from SPN - related party | 360,000 | 2 | 0 | — | — | |
| Accounts receivable | 157,000 | 0 | — | — | — | |
| Prepaid expenses and other current assets | 3 | 6 | 8 | 13 | 13 | |
| Total current assets | 49 | 39 | 175 | 195 | 304 | |
| Property and equipment, net | 8 | 12 | 18 | 23 | 18 | |
| Operating lease assets | 72 | 81 | 90 | 111 | 18 | |
| Restricted cash | 9 | 9 | 8 | 8 | 8 | |
| Other non-current assets | 31,000 | 31,000 | 2 | 10 | 5 | |
| Total assets | 138 | 140 | 359 | 349 | 355 | |
| Accounts payable | 2 | 4 | 4 | 17 | 14 | |
| Accrued expenses and other current liabilities | 4 | 11 | 23 | 60 | 45 | |
| Accrued liabilities due to SPN - related party | 3 | 18 | 0 | — | — | |
| Operating lease liabilities | 10 | 9 | 6 | 4 | 7 | |
| Total current liabilities | 19 | 41 | 99 | 86 | 82 | |
| Operating lease liabilities, net of current portion | 73 | 83 | 92 | 108 | 18 | |
| Other long-term liabilities | 2 | 2 | 2 | 1 | 11 | |
| Total liabilities | 94 | 126 | 403 | 338 | 223 | |
| Commitments and contingencies (Note 10) | — | — | — | — | — | |
| Preferred stock, $0.001 par value; 10,000,000 shares authorized at December 31, 2025 and 2024; no shares issued and outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value; 360,000,000 shares authorized at December 31, 2025 and 2024, respectively; 9,556,446 and 8,650,227 shares issued and outstanding at December 31, 2025 and 2024, respectively | 10,000 | 9,000 | 135,000 | 125,000 | 92,000 | |
| Additional paid-in capital | 1,017 | 992 | 933 | 875 | 746 | |
| Accumulated deficit | −972 | −978 | −978 | −865 | −614 | |
| Total stockholders' equity | 44 | 14 | −45 | 11 | 132 | |
| Total liabilities and stockholders' equity | 138 | 140 | 359 | 349 | 355 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 11 | 21 | 34 | 25 | 20 | |
| Depreciation and amortization expense | 4 | 5 | 6 | 7 | 6 | |
| Non-cash operating lease cost | 8 | 9 | 9 | 5 | 3 | |
| Net (accretion) amortization of (discounts) premiums on investments | 0 | 0 | −236,000 | 688,000 | 498,000 | |
| Gain on sale of VOWST Business, net of transaction costs | 0 | −147 | 0 | 0 | — | |
| Amortization of debt issuance costs | 0 | 1 | 1 | 705,000 | 3 | |
| Loss associated with extinguishment of debt | 0 | 23 | 2 | 0 | 0 | |
| (Gain)/loss on disposal of fixed assets | −192,000 | 317,000 | 0 | 0 | — | |
| Impairment of long-lived assets | 0 | 3 | 0 | 0 | — | |
| Change in fair value of warrant liabilities | 0 | −546,000 | −2 | 0 | 0 | |
| Collaboration (profit) loss sharing - related party (1) | 0 | 0 | 5 | 1 | — | |
| Accounts receivable due from SPN - related party | 2 | −2 | 0 | 0 | — | |
| Prepaid expenses and other current and non-current assets | 3 | 987,000 | −29 | −13 | −12 | |
| Accounts receivable | −157,000 | 0 | 0 | 0 | 9 | |
| Collaboration receivable - related party | 0 | 9 | −9 | 0 | 0 | |
| Inventories | 0 | −34 | −30 | 0 | 0 | |
| Deferred income - related party | 0 | −4 | 8 | 0 | 0 | |
| Deferred revenue - related party | 0 | 0 | −1 | −7 | −4 | |
| Accounts payable | −2 | −3 | −12 | 2 | 9 | |
| Accrued liabilities due to SPN - related party | −14 | −16 | 0 | 0 | — | |
| Operating lease liabilities | −9 | −6 | −2 | −4 | −4 | |
| Accrued expenses and other current and long-term liabilities | −7 | −10 | 16 | 3 | 43 | |
| Net cash provided by (used in) operating activities | 1 | −149 | −117 | −229 | 7 | |
| Purchases of property and equipment | −252,000 | −380,000 | −8 | −10 | −10 | |
| Proceeds from sales of property and equipment | 210,000 | 0 | 0 | — | — | |
| Purchases of investments | 0 | 0 | −4 | −48 | −96 | |
| Sales and maturities of investments | 0 | 0 | 23 | 140 | 170 | |
| Sales of restricted investments | 0 | 1 | 0 | 0 | — | |
| Proceeds from sale of VOWST Business | 0 | 141 | 0 | 0 | — | |
| Net cash (used in) provided by investing activities | −42,000 | 142 | 11 | 82 | 64 | |
| Proceeds from at the market equity offering, net of issuance costs | 13 | 24 | 18 | 4 | 0 | |
| Proceeds from exercise of stock options | 501,000 | 0 | 877,000 | 966,000 | 1 | |
| Proceeds from Securities Purchase Agreement - related party | 0 | 14 | 0 | 0 | — | |
| Issuance of common stock under ESPP | 230,000 | 487,000 | 2 | 2 | 827,000 | |
| Proceeds from issuance of debt, net of issuance costs | 0 | 0 | 103 | 28 | 0 | |
| Repayment of notes payable | 0 | −128 | −53 | −2 | −948,000 | |
| Net cash provided by (used in) financing activities | 14 | −90 | 72 | 130 | 1 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 15 | −97 | −35 | −17 | 72 | |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | 0 | −1,000 | 2,000 | −1,000 | −1,000 | |
| Cash paid for interest | 0 | 11 | 13 | 5 | 2 | |
| Property and equipment purchases included in accounts payable and accrued expenses | 0 | 0 | 16,000 | 2 | 874,000 | |
| Lease liability arising from obtaining right-of-use assets | 0 | 0 | 3 | 91 | 12 | |
| Prepaid rent reclassified to right-of-use assets | 0 | 0 | 5 | 7 | 0 | |
| Recognition of warrant liabilities | 0 | 0 | 2 | 0 | 0 | |
| Warrants issued related to prior credit facility with Oaktree and recorded as debt discount | 0 | 0 | 3 | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Seres Therapeutics, Inc.'s CIK number?
Seres Therapeutics, Inc.'s SEC CIK number is 0001609809 (1609809). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Seres Therapeutics, Inc.'s SEC filings?
All of Seres Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Seres Therapeutics, Inc. last report earnings?
Seres Therapeutics, Inc. (MCRB) most recently filed an earnings 8-K with the SEC on May 5, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-205009). This is Seres Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Seres Therapeutics, Inc.'s most recent earnings 8-K?
Seres Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 5, 2026 under accession 0001193125-26-205009. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Seres Therapeutics, Inc.'s latest earnings 8-K →
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