Nurix Therapeutics, Inc.
Business
Nurix Therapeutics is a clinical-stage biopharmaceutical company discovering and developing targeted protein degradation medicines for cancer and inflammatory diseases. The company offers three clinical-stage drug candidates: bexobrutideg (a BTK degrader), zelebrudomide (a dual BTK and cereblon neosubstrate degrader), and NX-1607 (a CBL-B inhibitor), along with a preclinical pipeline including degrader antibody conjugates. Nurix operates through wholly owned programs and partnership collaborations with Gilead, Sanofi, and Pfizer, leveraging its proprietary DEL-AI platform to identify novel small-molecule degraders across oncology, inflammation, and immunology indications globally.
Summary from 10-K filed 2026-01-28
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-11-30 | FY 2024 2024-11-30 | FY 2023 2023-11-30 | FY 2022 2022-11-30 | FY 2021 2021-11-30 |
|---|---|---|---|---|---|---|
| Total revenue | 84 | 55 | 77 | 39 | — | |
| Research and development | 317 | 222 | 189 | 184 | 116 | |
| General and administrative | 53 | 46 | 43 | 38 | 31 | |
| Total operating expenses | 370 | 268 | 232 | 222 | 148 | |
| Loss from operations | −286 | −213 | −155 | −184 | −118 | |
| Interest and other income, net | 22 | 20 | 11 | 4 | 823,000 | |
| Loss before income taxes | −264 | −193 | −144 | −180 | −117 | |
| Provision for income taxes | 760,000 | 270,000 | 0 | 0 | 131,000 | |
| Net loss | −264 | −194 | −144 | −180 | −117 | |
| Net loss per share, basic (in USD per share) | −3.05 | −2.88 | −2.65 | −3.71 | −2.73 | |
| Net loss per share, diluted (in USD per share) | −3.05 | −2.88 | −2.65 | −3.71 | −2.73 | |
| Weighted-average number of shares outstanding, basic (in shares) | 87 | 67 | 54 | 49 | 43 | |
| Weighted-average number of shares outstanding, diluted (in shares) | 87 | 67 | 54 | 49 | 43 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-11-30 | FY 2024 2024-11-30 | FY 2023 2023-11-30 | FY 2022 2022-11-30 | FY 2021 2021-11-30 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 247 | 110 | 55 | 64 | 81 | |
| Marketable securities | 346 | 500 | 233 | — | — | |
| Prepaid expenses and other current assets | 14 | 10 | 8 | 9 | 9 | |
| Total current assets | 607 | 619 | 296 | 318 | 311 | |
| Operating lease right-of-use assets | 51 | 28 | 31 | 12 | 14 | |
| Property and equipment, net | 22 | 18 | 17 | 17 | 11 | |
| Restricted cash | 1 | 900,000 | 901,000 | 901,000 | 300,000 | |
| Other assets | 7 | 3 | 4 | 4 | 3 | |
| Total assets | 688 | 669 | 356 | 417 | 477 | |
| Accounts payable | 11 | 11 | 6 | 5 | 7 | |
| Accrued expenses and other current liabilities | 55 | 38 | 25 | 22 | 15 | |
| Operating lease liabilities, current | 3 | 8 | 7 | 6 | 4 | |
| Deferred revenue, current | 18 | 38 | 48 | 38 | 41 | |
| Total current liabilities | 86 | 96 | 87 | 71 | 66 | |
| Operating lease liabilities, net of current portion | 53 | 20 | 23 | 6 | 9 | |
| Deferred revenue, net of current portion | 10 | 26 | 45 | 36 | 59 | |
| Total liabilities | 149 | 142 | 155 | 113 | 134 | |
| Commitments and contingencies (Note 6) | — | — | — | — | — | |
| Preferred stock, $0.001 par value 10,000,000 shares authorized as of November 30, 2025 and 2024; no shares issued and outstanding as of November 30, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value 500,000,000 shares authorized as of November 30, 2025 and 2024; 101,807,484 and 75,870,718 shares issued and outstanding as of November 30, 2025 and 2024, respectively | 102,000 | 76,000 | 49,000 | 47,000 | 45,000 | |
| Additional paid-in capital | 1,542 | 1,266 | 746 | 709 | 564 | |
| Accumulated other comprehensive income | 105,000 | 150,000 | −655,000 | −4 | −608,000 | |
| Accumulated deficit | −1,000 | −739 | −545 | −401 | −221 | |
| Total stockholders equity | 539 | 527 | 200 | 304 | 342 | |
| Total liabilities and stockholders equity | 688 | 669 | 356 | 417 | 477 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-11-30 | FY 2024 2024-11-30 | FY 2023 2023-11-30 | FY 2022 2022-11-30 | FY 2021 2021-11-30 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 9 | 9 | 8 | 5 | 3 | |
| Stock-based compensation | 38 | 34 | 34 | 28 | 16 | |
| Net accretion of discount on marketable securities | −10 | −11 | −5 | 426,000 | 2 | |
| Loss on disposal of property and equipment | 89,000 | 31,000 | 556,000 | 9,000 | 128,000 | |
| Amortization of operating lease right-of-use assets | 10 | 7 | 6 | 5 | 3 | |
| Other | 0 | 286,000 | 0 | 201,000 | 0 | |
| Prepaid expenses and other assets | −6 | −459,000 | 2 | −1 | −5 | |
| Accounts payable | −630,000 | 5 | 2 | 85,000 | 2 | |
| Deferred revenue | −37 | −29 | 20 | −27 | 14 | |
| Operating lease liabilities | −5 | −6 | −6 | −5 | −5 | |
| Accrued expenses and other current liabilities | 17 | 12 | 3 | 7 | 6 | |
| Net cash used in operating activities | −249 | −173 | −81 | −160 | −84 | |
| Purchases of marketable securities | −456 | −708 | −246 | −239 | — | |
| Maturities of marketable securities | 618 | 460 | 323 | 279 | 239 | |
| Purchases of property and equipment | −14 | −9 | −8 | −12 | −6 | |
| Net cash provided by (used in) investing activities | 148 | −258 | 68 | 27 | −108 | |
| Proceeds from issuances of common stock and pre-funded warrants, net of issuance costs | 235 | 189 | 0 | 95 | — | |
| Proceeds from exercise of stock options and pre-funded warrants | 2 | 5 | 988,000 | 1 | — | |
| Proceeds from issuance of common stock under employee stock purchase plan | 2 | 2 | 2 | 2 | 2 | |
| Proceeds from issuances of common stock in "at the market" financing, net of issuance costs | 0 | 290 | 0 | 19 | 150 | |
| Repurchase of unvested early exercised stock options | 0 | −15,000 | 0 | 0 | — | |
| Net cash provided by financing activities | 239 | 486 | 3 | 117 | 154 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 137 | 55 | −10 | −15 | −39 | |
| Additions to property and equipment included in accounts payable and accrued expenses and other current liabilities | 1 | 2 | 632,000 | 1 | 3 | |
| Right-of-use assets recognized in exchange for lease obligations | 32 | 4 | 24 | 5 | 2 | |
| Capitalized stock-based compensation related to internal-use software development | 20,000 | 14,000 | 74,000 | 69,000 | 0 | |
| Issuance costs related to equity financing included in accrued expenses and other current liabilities | 371,000 | 0 | 0 | — | — | |
| Deferred issuance costs included in accounts payable and accrued expenses and other current liabilities | 0 | 117,000 | 0 | 0 | — | |
| Deferred issuance costs recognized related to the "at the market" financing | 0 | 394,000 | 0 | 72,000 | 0 | |
| Vesting of early exercised stock options | 0 | 33,000 | 117,000 | 145,000 | 239,000 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Nurix Therapeutics, Inc.'s CIK number?
Nurix Therapeutics, Inc.'s SEC CIK number is 0001549595 (1549595). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Nurix Therapeutics, Inc.'s SEC filings?
All of Nurix Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Nurix Therapeutics, Inc. last report earnings?
Nurix Therapeutics, Inc. (NRIX) most recently filed an earnings 8-K with the SEC on Jul 9, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001549595-26-000038). This is Nurix Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Nurix Therapeutics, Inc.'s most recent earnings 8-K?
Nurix Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed Jul 9, 2026 under accession 0001549595-26-000038. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Nurix Therapeutics, Inc.'s latest earnings 8-K →
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