NextCure, Inc.
Business
NextCure, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative medicines for cancer patients who do not respond to current therapies, including antibody-drug conjugates (ADCs). Its main products and candidates include the B7-H4 targeted ADC LNCB74, clinical oncology programs NC410 and NC525, and preclinical non-oncology programs NC181 (ApoE4 for Alzheimer’s) and NC605 (Siglec-15 for bone diseases). Key business activities include clinical development, co-development collaborations (notably with LigaChem), proprietary manufacturing capabilities and intellectual property licensing. The company advances candidates through clinical trials, collaborations, partnerships and potential licensing across domestic and international markets.
Summary from filing dated 2025-03-06
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 45 | 41 | 48 | 54 | 50 | |
| General and administrative | 13 | 16 | 20 | 22 | 21 | |
| Restructuring and asset impairment charges | — | 3 | — | — | — | |
| Total operating expenses | 58 | 60 | 68 | 76 | 71 | |
| Loss from operations | −58 | −60 | −68 | −76 | −71 | |
| Other income, net | 2 | 4 | 5 | 1 | 1 | |
| Net loss | −56 | −56 | −63 | −75 | −69 | |
| Basic (in dollars per share) | −19.65 | −23.88 | −2.25 | −2.69 | −2.51 | |
| Diluted (in dollars per share) | −19.65 | −23.88 | −2.25 | −2.69 | −2.51 | |
| Basic (in shares) | 3 | 2 | 28 | 28 | 28 | |
| Diluted (in shares) | 3 | 2 | 28 | 28 | 28 | |
| Unrealized gain on marketable securities | 17,000 | 226,000 | 1 | −831,000 | −1 | |
| Total comprehensive loss | −56 | −55 | −61 | −76 | −71 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 26 | 28 | 13 | 27 | 12 | |
| Marketable securities | 16 | 41 | 95 | 133 | 207 | |
| Prepaid expenses and other current assets | 2 | 3 | 4 | 4 | 8 | |
| Total current assets | 44 | 72 | 113 | 164 | 228 | |
| Property and equipment, net | 3 | 5 | 9 | 12 | 14 | |
| Right of use assets | 3 | 3 | 4 | 5 | — | |
| Other assets | 546,000 | 332,000 | 2 | 3 | 577,000 | |
| Total assets | 50 | 81 | 128 | 184 | 242 | |
| Accounts payable | 2 | 5 | 2 | 4 | 2 | |
| Accrued liabilities and other liabilities | 9 | 4 | 5 | 5 | 5 | |
| Total current liabilities | 11 | 10 | 7 | 9 | 7 | |
| Lease liabilities, long term | 4 | 5 | 6 | 7 | — | |
| Other long-term liabilities | 526,000 | 661,000 | 785,000 | 899,000 | 2 | |
| Total liabilities | 15 | 15 | 14 | 17 | 9 | |
| Preferred stock, par value of $0.001 per share; 10,000,000 shares authorized at December 31, 2025 and December 31, 2024; No shares issued and outstanding at December 31, 2025 and December 31, 2024 | — | — | — | — | — | |
| Common stock, par value of $0.001 per share; 100,000,000 shares authorized at December 31, 2025 and December 31, 2024; 3,505,621 and 2,333,896 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 4,000 | 2,000 | 28,000 | 28,000 | 28,000 | |
| Additional paid-in capital | 471 | 446 | 439 | 431 | 421 | |
| Accumulated other comprehensive income | 21,000 | 4,000 | −222,000 | −1 | −663,000 | |
| Accumulated deficit | −436 | −380 | −324 | −262 | −187 | |
| Total stockholders' equity | 35 | 65 | 114 | 168 | 233 | |
| Total liabilities and stockholders' equity | 50 | 81 | 128 | 184 | 242 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −56 | −56 | −63 | −75 | −69 | |
| Depreciation and amortization | 2 | 3 | 4 | 4 | 4 | |
| Amortization of premiums and discounts on marketable securities | −481,000 | −1 | −756,000 | 3 | 3 | |
| Stock-based compensation | 3 | 6 | 8 | 10 | 10 | |
| Asset impairment | — | 2 | — | — | — | |
| Noncash operating lease expense | 587,000 | 561,000 | 573,000 | 356,000 | — | |
| Prepaid expenses and other assets | 1 | 3 | 1 | 2 | −5 | |
| Accounts payable | −3 | 3 | −2 | 2 | −2 | |
| Accrued liabilities and other liabilities | 4 | −332,000 | −304,000 | −641,000 | −178,000 | |
| Lease liabilities | −1 | −796,000 | −656,000 | — | — | |
| Other long-term liabilities | −135,000 | −124,000 | −114,000 | — | 2 | |
| Net cash used in operating activities | −50 | −41 | −53 | −54 | −57 | |
| Sales and maturities of marketable securities | 52 | 104 | 114 | 105 | 195 | |
| Purchases of marketable securities | −27 | −48 | −74 | −35 | −156 | |
| Purchases of property and equipment | — | −474,000 | −820,000 | −2 | −2 | |
| Net cash provided by investing activities | 26 | 55 | 39 | 68 | 37 | |
| Proceeds from exercise of stock options | — | 23,000 | 5,000 | 66,000 | 208,000 | |
| Proceeds from shares issued under ESPP | 36,000 | 82,000 | 149,000 | 134,000 | — | |
| Net cash provided by financing activities | 22 | 144,000 | 154,000 | 200,000 | −3 | |
| Net increase (decrease) in cash and cash equivalents | −2 | 15 | −14 | 14 | −24 | |
| Cash paid for interest | 62,000 | 72,000 | 81,000 | 90,000 | 162,000 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is NextCure, Inc.'s CIK number?
NextCure, Inc.'s SEC CIK number is 0001661059 (1661059). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find NextCure, Inc.'s SEC filings?
All of NextCure, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did NextCure, Inc. last report earnings?
NextCure, Inc. (NXTC) most recently filed an earnings 8-K with the SEC on May 7, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001104659-26-057171). This is NextCure, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is NextCure, Inc.'s most recent earnings 8-K?
NextCure, Inc.'s latest earnings 8-K (Item 2.02) was filed May 7, 2026 under accession 0001104659-26-057171. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View NextCure, Inc.'s latest earnings 8-K →
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