OMEROS CORP
Business
Omeros Corporation is a commercial-stage biotechnology company that discovers and develops first-in-class protein and small-molecule therapeutics for complement-mediated diseases, cancers, and addictive or compulsive disorders. Its first FDA-approved product is YARTEMLEA (narsoplimab), a monoclonal antibody targeting MASP-2 for treating hematopoietic stem cell transplant-associated thrombotic microangiopathy, with commercial sales launched in January 2026. The company operates through complement-inhibitor programs targeting lectin and alternative pathways, PDE7 inhibitor programs for addiction and movement disorders, an oncology program for acute myeloid leukemia, and infectious-disease platforms, retaining worldwide marketing and distribution rights while relying on contract manufacturers.
Summary from 10-K filed 2026-03-31
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 81 | 120 | 115 | 113 | 119 | |
| Selling, general and administrative | 42 | 47 | 50 | 51 | 55 | |
| Total costs and expenses | 123 | 167 | 165 | 163 | 174 | |
| Loss from operations | −123 | −167 | −165 | −163 | −174 | |
| Gain on sale of zaltenibart | 238 | 0 | 0 | — | — | |
| Interest and other income | 4 | 11 | 16 | 4 | 2 | |
| Interest expense, net of remeasurement adjustments and other | 960,000 | −25 | −31 | −23 | — | |
| Gain (loss) on change in fair value of financial instruments, net | −137 | 19,000 | 0 | — | — | |
| Loss from continuing operations before income tax expense | −3 | −180 | −175 | −182 | −192 | |
| Income tax expense | −2 | −2 | 0 | 0 | 0 | |
| Net loss from continuing operations, net of tax | −5 | −183 | −175 | −182 | −192 | |
| Net income from discontinued operations, net of tax | 1 | 26 | 57 | 229 | 386 | |
| Net loss | −3 | −157 | −118 | 47 | 194 | |
| Net loss from continuing operations (in dollars per share) | −0.08 | −3.14 | −2.79 | −2.9 | −3.07 | |
| Net loss from continuing operations (in dollars per share) | −0.08 | −3.14 | −2.79 | −2.9 | −3.07 | |
| Net income from discontinued operations (in dollars per share) | 0.03 | 0.44 | 0.91 | 3.66 | 6.19 | |
| Net income from discontinued operations (in dollars per share) | 0.03 | 0.44 | 0.91 | 3.66 | 6.19 | |
| Net loss (in dollars per share) | −0.05 | −2.7 | −1.88 | 0.76 | 3.12 | |
| Net loss (in dollars per share) | −0.05 | −2.7 | −1.88 | 0.76 | 3.12 | |
| Weighted-average shares used to compute basic and diluted net income (loss) per share (in shares) | 64 | 58 | 63 | 63 | 62 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 10 | 3 | 7 | 11 | 101 | |
| Short-term investments | 162 | 87 | 165 | 184 | 56 | |
| OMIDRIA contract royalty asset | 25 | 29 | 29 | 29 | 44 | |
| Receivables | 11 | 8 | 8 | 213 | 38 | |
| Prepaid expense and other assets | 8 | 7 | 9 | 6 | 8 | |
| Total current assets | 216 | 134 | 218 | 443 | 248 | |
| OMIDRIA contract royalty asset, non-current | 96 | 124 | 139 | 123 | 140 | |
| Right of use assets | 11 | 15 | 19 | 22 | 28 | |
| Property and equipment, net | 2 | 3 | 2 | 1 | — | |
| Restricted investments | 1 | 1 | 1 | 1 | 1 | |
| Total assets | 326 | 277 | 378 | 591 | 419 | |
| Accounts payable | 5 | 6 | 8 | 6 | 13 | |
| Accrued expenses | 29 | 26 | 32 | 31 | 33 | |
| OMIDRIA royalty obligation | 21 | 21 | 9 | 1 | — | |
| 2026 Notes, net | 17 | 0 | 0 | 94 | — | |
| Term debt | 0 | 21 | — | — | — | |
| Lease liabilities | 6 | 6 | 5 | 4 | 5 | |
| Total current liabilities | 78 | 80 | 53 | 136 | 52 | |
| OMIDRIA royalty obligation, non-current | 147 | 196 | 117 | — | — | |
| 2026 and 2029 Notes, non-current, net | 51 | 97 | 213 | 221 | 313 | |
| Term debt, non-current, net | 0 | 70 | 0 | — | — | |
| Lease liabilities, non-current | 7 | 13 | 18 | 22 | — | |
| Other accrued liabilities, non-current | 6 | 5 | 2 | 444,000 | 1 | |
| Commitments and Contingencies | — | — | — | — | — | |
| Preferred stock, par value $0.01 per share, 20,000,000 shares authorized; none issued and outstanding at December 31, 2025 and December 31, 2024 | 0 | 0 | 0 | 0 | — | |
| Common stock, par value $0.01 per share, 150,000,000 shares authorized at December 31, 2025 and December 31, 2024; 71,670,791 and 58,044,465 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively. | 716,000 | 580,000 | 611,000 | 628,000 | 626,000 | |
| Additional paid-in capital | 792 | 727 | 728 | — | — | |
| Accumulated deficit | −914 | −910 | −754 | −636 | −683 | |
| Total shareholders equity (deficit) | −121 | −183 | −25 | 86 | 24 | |
| Total liabilities and shareholders equity (deficit) | 326 | 277 | 378 | 591 | 419 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 8 | 10 | 12 | 14 | 18 | |
| Depreciation and amortization | 964,000 | 950,000 | 920,000 | 952,000 | 1 | |
| Non-cash interest remeasurement on the OMIDRIA royalty obligation | −33 | −6 | 0 | 2 | 0 | |
| Non-cash interest on OMIDRIA contract royalty asset | −15 | −17 | −15 | −19 | 0 | |
| Remeasurement on OMIDRIA contract royalty asset | 13 | −8 | −41 | −14 | 0 | |
| Accretion on U.S. government treasury bills, net | 0 | −4 | −9 | 0 | 0 | |
| OMIDRIA contract royalty asset | 34 | 40 | 41 | 65 | 0 | |
| Accounts payable and accrued expense | 5 | −5 | 5 | −11 | 15 | |
| Receivables | −3 | 357,000 | 205 | −175 | −34 | |
| Prepaid expenses and other | −1 | 517,000 | −3 | 934,000 | 6 | |
| Net cash provided by (used in) operating activities | −116 | −149 | 75 | −86 | −110 | |
| Gross cash proceeds from sale of zaltenibart | 240 | 0 | 0 | — | — | |
| Proceeds from the sale and maturities of investments | 110 | 1,070 | 1,046 | 302 | 100 | |
| Purchases of investments | −185 | −987 | −1,019 | −429 | −32 | |
| Purchases of property and equipment | −65,000 | −165,000 | −426,000 | −113,000 | −277,000 | |
| Net cash provided by investing activities | 165 | 82 | 27 | −128 | 194 | |
| Proceeds upon exercise of stock options | 8 | 547,000 | 150,000 | 415,000 | — | |
| Repayment of term debt principal | −67 | 0 | 0 | — | — | |
| Principal payments on OMIDRIA royalty obligation | −15 | −19 | −1 | −417,000 | 0 | |
| Payments on finance lease obligations | −749,000 | −829,000 | −555,000 | −750,000 | −2 | |
| Proceeds from sale of future royalties | 0 | 116 | 0 | 125 | — | |
| Payment on maturity of 2023 Notes | 0 | 0 | −95 | 0 | 0 | |
| Cash paid to repurchase 2026 Notes | 0 | −22 | −5 | 0 | — | |
| Repurchases of common stock | 0 | −12 | −5 | 0 | 0 | |
| Net cash provided by (used in) financing activities | −42 | 63 | −106 | 124 | 6 | |
| Net increase (decrease) in cash and cash equivalents | 6 | −4 | −4 | −90 | 90 | |
| Cash paid for interest | 35 | 36 | 30 | 19 | 18 | |
| Cash paid for income taxes, net | 153,000 | 165,000 | 3 | 80,000 | — | |
| Equipment acquired under finance lease | 0 | 2 | 952,000 | 40,000 | 289,000 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is OMEROS CORP's CIK number?
OMEROS CORP's SEC CIK number is 0001285819 (1285819). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find OMEROS CORP's SEC filings?
All of OMEROS CORP's EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did OMEROS CORP last report earnings?
OMEROS CORP (OMER) most recently filed an earnings 8-K with the SEC on May 13, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001437749-26-016718). This is OMEROS CORP's most recent earnings filing of record — not a forecast of its next earnings date.
What is OMEROS CORP's most recent earnings 8-K?
OMEROS CORP's latest earnings 8-K (Item 2.02) was filed May 13, 2026 under accession 0001437749-26-016718. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View OMEROS CORP's latest earnings 8-K →
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