Oric Pharmaceuticals, Inc.
Business
ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing therapies that overcome resistance in cancer. It advances a pipeline of small-molecule clinical and discovery-stage product candidates, including a brain-penetrant EGFR/HER2 inhibitor (ORIC-114), an allosteric PRC2 inhibitor (ORIC-944) and other programs (e.g., ORIC-533, ORIC-613). The company organizes around three areas of expertise—hormone-dependent cancers, precision oncology and key tumor dependencies—with integrated discovery, translational and clinical development capabilities. It conducts global clinical trials, forms collaborations with pharmaceutical partners for studies and supply, and plans to commercialize in key markets either directly or with partners while relying on third-party manufacturers.
Summary from filing dated 2025-02-18
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 110 | 114 | 85 | 62 | 57 | |
| General and administrative | 33 | 29 | 26 | 25 | 22 | |
| Total operating expenses | 143 | 143 | 111 | 92 | 79 | |
| Loss from operations | −143 | −143 | −111 | −92 | −79 | |
| Other income, net | 14 | 15 | 10 | 3 | 156,000 | |
| Net loss | −129 | −128 | −101 | −89 | −79 | |
| Unrealized gain on investments | 407,000 | 121,000 | 2 | −1 | −72,000 | |
| Comprehensive loss | −129 | −128 | −99 | −90 | −79 | |
| Net loss per share, basic | −1.47 | −1.83 | −1.96 | −2.25 | −2.07 | |
| Net loss per share, diluted | −1.47 | −1.83 | −1.96 | −2.25 | −2.07 | |
| Weighted-average shares outstanding, basic | 88 | 70 | 51 | 40 | 38 | |
| Weighted-average shares outstanding, diluted | 88 | 70 | 51 | 40 | 38 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 46 | 59 | 23 | 67 | 226 | |
| Short-term investments | 236 | 197 | 185 | 139 | 11 | |
| Prepaid expenses and other current assets | 7 | 6 | 4 | 4 | 4 | |
| Total current assets | 288 | 262 | 213 | 210 | 241 | |
| Long-term investments | 111 | 0 | 27 | 22 | 43 | |
| Property and equipment, net | 2 | 3 | 3 | 3 | 2 | |
| Other assets | 7 | 9 | 10 | 12 | 12 | |
| Total assets | 409 | 274 | 252 | 247 | 299 | |
| Accounts payable | 4 | 2 | 944,000 | 1 | 2 | |
| Accrued liabilities | 17 | 23 | 20 | 14 | 13 | |
| Total current liabilities | 20 | 25 | 20 | 15 | 15 | |
| Other long-term liabilities | 4 | 6 | 7 | 9 | 11 | |
| Total liabilities | 25 | 31 | 28 | 25 | 26 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, $0.0001 par value; 200,000,000 shares authorized; no shares issued and outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value; 1,000,000,000 shares authorized; 98,528,949 and 71,021,855 shares issued and outstanding at December 31, 2025 and 2024, respectively | 11,000 | 7,000 | 6,000 | 5,000 | 4,000 | |
| Additional paid-in capital | 1,076 | 806 | 659 | 558 | 518 | |
| Accumulated deficit | −692 | −563 | −435 | −334 | −245 | |
| Accumulated other comprehensive income | 786,000 | 379,000 | 258,000 | −1 | −103,000 | |
| Total stockholders' equity | 384 | 243 | 224 | 222 | 273 | |
| Total liabilities and stockholders' equity | 409 | 274 | 252 | 247 | 299 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 1 | 1 | 1 | 1 | 900,000 | |
| Stock-based compensation expense | 25 | 20 | 15 | 14 | 13 | |
| Accretion of discount on investments, net | −2 | −8 | −6 | −1 | 1 | |
| Prepaid expenses and other assets | 2 | 143,000 | 2 | 1 | 1 | |
| Accounts payable and accrued other liabilities | −7 | 2 | 3 | −1 | 3 | |
| Net cash used in operating activities | −111 | −113 | −86 | −75 | −60 | |
| Acquisitions of property and equipment | −712,000 | −1 | −849,000 | −2 | −939,000 | |
| Purchases of investments | −400 | −252 | −239 | −238 | −70 | |
| Maturities of investments | 253 | 275 | 197 | 131 | 229 | |
| Net cash (used in) provided by investing activities | −148 | 22 | −43 | −109 | 158 | |
| Proceeds from issuance of common stock and pre-funded warrants | 244 | 125 | 85 | 25 | 50 | |
| Issuance costs associated with financings | −2 | −168,000 | — | — | — | |
| Proceeds from issuance of common stock under ESPP | 1 | 1 | 826,000 | 545,000 | 0 | |
| Proceeds from stock option exercises | 2 | 631,000 | 59,000 | 79,000 | 986,000 | |
| Net cash provided by financing activities | 245 | 127 | 86 | 25 | 49 | |
| Net (decrease) increase in cash, cash equivalents and restricted cash | −14 | 36 | −43 | −159 | 148 |