PepGen Inc.
Business
PepGen Inc. is a clinical-stage biotechnology company developing oligonucleotide therapeutics using its proprietary Enhanced Delivery Oligonucleotide (EDO) platform, which uses cell-penetrating peptides to improve cellular uptake and nuclear delivery of therapeutic oligonucleotides. The company's lead candidate, PGN-EDODM1, is a peptide-conjugated phosphorodiamidate morpholino (PMO) targeting myotonic dystrophy type 1 (DM1) that has demonstrated robust splicing correction in Phase 1 trials. PepGen is conducting Phase 2 clinical trials (FREEDOM2) and an open-label extension study (FREEDOM-OLE) across multiple geographies including Canada, the U.K., South Korea, Australia, and New Zealand.
Summary from 10-K filed 2026-03-04
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 71 | 76 | 68 | 54 | 19 | |
| General and administrative | 23 | 21 | 17 | 14 | 8 | |
| Total operating expenses | 94 | 98 | 85 | 68 | 27 | |
| Operating loss | −94 | −98 | −85 | −68 | −27 | |
| Interest income | 4 | 7 | 6 | 3 | — | |
| Other (expense) income, net | −11,000 | −1,000 | −187,000 | 110,000 | −172,000 | |
| Total other income, net | 4 | 7 | 6 | 3 | −172,000 | |
| Net loss before income tax | −90 | −91 | −79 | −65 | −27 | |
| Income tax (expense) benefit | −49,000 | 617,000 | −100,000 | −4 | 0 | |
| Net loss | −90 | −90 | −79 | −69 | −27 | |
| Net loss per share, basic | −2.12 | −2.85 | −3.3 | −4.42 | −30.27 | |
| Net loss per share, diluted | −2.12 | −2.85 | −3.3 | −4.42 | −30.27 | |
| Weighted-average common shares outstanding, basic | 42 | 32 | 24 | 16 | 901,108 | |
| Weighted-average common shares outstanding, diluted | 42 | 32 | 24 | 16 | 901,108 | |
| Cumulative translation adjustment arising during the period | 0 | −50,000 | 104,000 | — | — | |
| Unrealized (loss) gain on marketable securities | −12,000 | 39,000 | 11,000 | — | — | |
| Comprehensive loss | −90 | −90 | −79 | — | — |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 61 | 49 | 81 | 182 | 133 | |
| Marketable securities | 88 | 71 | 30 | 0 | — | |
| Prepaid expenses and other current assets | 3 | 4 | 2 | 4 | 2 | |
| Total current assets | 151 | 124 | 113 | 186 | 140 | |
| Property and equipment, net | 2 | 4 | 5 | 3 | 636,000 | |
| Operating lease right-of-use asset | 19 | 21 | 24 | 27 | — | |
| Restricted cash | 2 | 2 | 2 | — | — | |
| Other assets | 372,000 | 426,000 | 442,000 | 1 | 3 | |
| Total assets | 174 | 151 | 143 | 217 | 144 | |
| Accounts payable | 822,000 | 2 | 1 | 1 | 3 | |
| Accrued expenses | 9 | 12 | 14 | 12 | 7 | |
| Operating lease liability | 3 | 3 | 3 | 6 | — | |
| Total current liabilities | 13 | 17 | 18 | 19 | 10 | |
| Operating lease liability, net of current portion | 14 | 16 | 17 | 19 | — | |
| Total liabilities | 26 | 32 | 35 | 38 | 11 | |
| Preferred stock, $0.0001 par value; 10,000,000 shares authorized at December 31, 2025 and 2024, respectively | — | — | — | — | — | |
| Common stock, $0.0001 par value; 500,000,000 shares authorized as of December 31, 2025 and 2024, respectively; 68,874,944 and 32,619,663 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 7,000 | 3,000 | 2,000 | 2,000 | — | |
| Additional paid-in capital | 509 | 390 | 290 | 283 | 2 | |
| Accumulated other comprehensive income | 11,000 | 23,000 | 34,000 | −81,000 | 17,000 | |
| Accumulated deficit | −361 | −271 | −181 | −103 | −34 | |
| Total stockholders' equity | 147 | 119 | 108 | 180 | −32 | |
| Total liabilities and stockholders' equity | 174 | 151 | 143 | 217 | 144 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 1 | 2 | 1 | 493,000 | 178,000 | |
| Stock-based compensation expense | 11 | 11 | 7 | 5 | 2 | |
| Amortization and interest accretion related to operating lease | 4 | 4 | −334,000 | — | — | |
| Amortization of premiums and accretion of discounts on marketable securities, net | −2 | −4 | −220,000 | — | — | |
| Impairment of long-lived assets | 701,000 | 0 | — | — | — | |
| Other non-cash adjustments | — | 70,000 | — | 134,000 | — | |
| Prepaids and other current and non-current assets | 1 | −1 | 2 | −2 | −2 | |
| Accounts payable | −935,000 | 722,000 | −369,000 | −1 | 3 | |
| Accrued expenses and other non-current liabilities | −3 | −2 | 1 | 6 | 7 | |
| Operating lease liabilities, current and non-current | −3 | −3 | −1 | −2 | — | |
| Net cash used in operating activities | −82 | −82 | −69 | −59 | −23 | |
| Purchases of property and equipment | −264,000 | −497,000 | −3 | −4 | −500,000 | |
| Purchases of marketable securities | −94 | −145 | −29 | — | — | |
| Maturities of marketable securities | 79 | 108 | — | — | — | |
| Net cash used in investing activities | −15 | −38 | −32 | −4 | −500,000 | |
| Issuance of common stock in public offering, net of underwriters' fees | 108 | 77 | — | — | — | |
| Payment of offering costs | −413,000 | −511,000 | −442,000 | −3 | −1 | |
| Issuance of common stock from At-the-Market Sales Agreement, net of underwriters' fees | — | 10 | — | 114 | — | |
| Proceeds from employee equity plans | 292,000 | 2 | 253,000 | 217,000 | — | |
| Net cash provided by financing activities | 108 | 89 | −189,000 | 112 | 148 | |
| Effect of exchange rate changes on cash | −16,000 | −62,000 | 286,000 | −316,000 | 33,000 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 11 | −31 | −101 | 49 | 125 | |
| Property and equipment included in accounts payable and accrued expenses | 20,000 | 31,000 | 14,000 | 363,000 | — | |
| Deferred offering costs in AP and accruals | 55,000 | — | — | — | 160,000 | |
| Cash paid for taxes | 82,000 | 71,000 | 3 | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is PepGen Inc.'s CIK number?
PepGen Inc.'s SEC CIK number is 0001835597 (1835597). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find PepGen Inc.'s SEC filings?
All of PepGen Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did PepGen Inc. last report earnings?
PepGen Inc. (PEPG) most recently filed an earnings 8-K with the SEC on May 12, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-219424). This is PepGen Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is PepGen Inc.'s most recent earnings 8-K?
PepGen Inc.'s latest earnings 8-K (Item 2.02) was filed May 12, 2026 under accession 0001193125-26-219424. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View PepGen Inc.'s latest earnings 8-K →
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