Personalis, Inc.
Business
Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and sequencing services used for translational research, biomarker discovery, personalized cancer therapies, clinical trials, and patient monitoring. Its main products and services include tumor-informed liquid biopsy MRD tests (NeXT Personal, NeXT Personal Dx), comprehensive tumor profiling (NeXT Dx, ImmunoID NeXT), and whole exome/genome sequencing (WES/WGS) for diagnostic partners and population initiatives. The company manages one operating segment focused on providing advanced cancer genomic tests and services for precision oncology and personalized testing. It sells primarily in the United States, Europe and Asia-Pacific through a small direct sales force and strategic co-commercialization partnerships (including Tempus) to pharmaceutical, diagnostics, academic, government and patient customers.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 70 | 85 | 73 | 65 | 85 | |
| Cost of revenue | 54 | 58 | 55 | 52 | 54 | |
| Research and development | 50 | 49 | 65 | 65 | 49 | |
| Selling, general and administrative | 54 | 46 | 50 | 64 | 48 | |
| Total costs and expenses | 158 | 153 | 183 | 181 | 151 | |
| Loss from operations | −88 | −68 | −110 | −116 | −65 | |
| Interest income | 7 | 6 | 6 | 2 | 367,000 | |
| Interest expense | −205,000 | −24,000 | −110,000 | −201,000 | −184,000 | |
| Other income (expense), net | −142,000 | −18 | −4 | 61,000 | −42,000 | |
| Loss before income taxes | −81 | −81 | −108 | −113 | −65 | |
| Provision for income taxes | 21,000 | 18,000 | 83,000 | 40,000 | 14,000 | |
| Net loss | −81 | −81 | −108 | −113 | −65 | |
| Net loss per share, basic | −0.91 | −1.37 | −2.25 | −2.48 | −1.49 | |
| Net loss per share, diluted | −0.91 | −1.37 | −2.25 | −2.48 | −1.49 | |
| Weighted-average shares outstanding, basic | 89 | 59 | 48 | 46 | 44 | |
| Weighted-average shares outstanding, diluted | 89 | 59 | 48 | 46 | 44 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 124 | 91 | 57 | 89 | 106 | |
| Short-term investments | 116 | 94 | 57 | 79 | 181 | |
| Accounts receivable, net | 16 | 8 | 18 | 17 | 18 | |
| Inventory and other deferred costs | 6 | 6 | 10 | 9 | 6 | |
| Prepaid expenses and other current assets | 6 | 4 | 4 | 7 | 7 | |
| Total current assets | 268 | 203 | 147 | 200 | 318 | |
| Property and equipment, net | 45 | 48 | 57 | 62 | 20 | |
| Operating lease right-of-use assets | 15 | 16 | 18 | 26 | 54 | |
| Other long-term assets | 6 | 3 | 3 | 5 | 5 | |
| Total assets | 334 | 270 | 225 | 293 | 397 | |
| Accounts payable | 13 | 6 | 15 | 13 | 9 | |
| Accrued and other current liabilities | 25 | 22 | 24 | 19 | 18 | |
| Contract liabilities | 2 | 3 | 3 | 1 | 4 | |
| Total current liabilities | 40 | 31 | 47 | 33 | 31 | |
| Long-term operating lease liabilities | 32 | 35 | 38 | 41 | 53 | |
| Other long-term liabilities | 1 | 1 | 5 | 389,000 | 2 | |
| Total liabilities | 73 | 67 | 96 | 75 | 86 | |
| Commitments and contingencies (Note 11) | — | — | — | — | — | |
| Preferred stock, $0.0001 par value 10,000,000 shares authorized; none issued | — | — | — | — | — | |
| Common stock, $0.0001 par value - 200,000,000 shares authorized; 102,475,891and 85,171,146 shares issued and outstanding, respectively | 10,000 | 9,000 | 5,000 | 5,000 | 4,000 | |
| Additional paid-in capital | 892 | 753 | 598 | 579 | 558 | |
| Accumulated other comprehensive income (loss) | 104,000 | −23,000 | −222,000 | −912,000 | −166,000 | |
| Accumulated deficit | −631 | −550 | −469 | −360 | −247 | |
| Total stockholders equity | 261 | 203 | 129 | 218 | 310 | |
| Total liabilities and stockholders equity | 334 | 270 | 225 | 293 | 397 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −81 | −81 | −108 | −113 | −65 | |
| Stock-based compensation expense | 9 | 11 | 14 | 19 | 14 | |
| Depreciation and amortization | 10 | 11 | 11 | 8 | 6 | |
| Noncash operating lease cost | 1 | 1 | 2 | 4 | 3 | |
| Noncash gain related to liability | — | 18 | — | — | — | |
| Amortization of discount on short-term investments | −4 | −3 | −2 | 57,000 | 2 | |
| Other | −302,000 | 93,000 | 153,000 | 103,000 | 169,000 | |
| Accounts receivable | −8 | 10 | −1 | 2 | −12 | |
| Inventories and other deferred costs | −204,000 | 4 | −2 | −3 | 29,000 | |
| Prepaid expenses and other assets | −2 | 1 | 4 | 484,000 | −3 | |
| Accounts payable | 5 | −9 | 5 | 3 | −1 | |
| Accrued and other current liabilities | 2 | −2 | 742,000 | −1 | 3 | |
| Contract liabilities | −2 | −4 | 6 | −3 | −17 | |
| Operating lease liabilities | −4 | −4 | 894,000 | 13 | −962,000 | |
| Other long-term liabilities | −1 | 1 | −10,000 | −419,000 | −291,000 | |
| Net cash used in operating activities | −75 | −45 | −56 | −70 | −71 | |
| Purchases of available-for-sale debt securities | −210 | −122 | −104 | −121 | −267 | |
| Proceeds from maturities of available-for-sale debt securities | 192 | 88 | 128 | 224 | 213 | |
| Purchases of property and equipment | −5 | −2 | −11 | −50 | −11 | |
| Proceeds from sales of property and equipment | — | 242,000 | — | — | — | |
| Net cash used in investing activities | −23 | −35 | 13 | 53 | −60 | |
| Proceeds from sales of common stock under ATM facility, net of commissions | 127 | 30 | 4 | — | 162 | |
| Proceeds from exercise of Tempus Warrants | — | 18 | — | — | — | |
| Proceeds from sale of common stock under Tempus Investment Agreement | — | 18 | — | — | — | |
| Proceeds from sale of common stock under Merck Investment Agreement | — | 50 | — | — | — | |
| Payment of costs related to Tempus and Merck Investment Agreements | −189,000 | −1 | — | — | — | |
| Proceeds from loans | 3 | — | 3 | 1 | 5 | |
| Repayments of loans | −2 | −1 | −3 | −2 | −2 | |
| Proceeds from issuance of common stock under equity incentive plans | 3 | 770,000 | 1 | — | — | |
| Net cash provided by financing activities | 130 | 115 | 11 | 1 | 170 | |
| Effect of exchange rates on cash, cash equivalents and restricted cash | 6,000 | −22,000 | −16,000 | −127,000 | 47,000 | |
| Net change in cash, cash equivalents and restricted cash | 33 | 34 | −32 | −16 | 39 | |
| Cash paid for income taxes, net of refunds | 23,000 | 38,000 | 64,000 | 47,000 | 39,000 | |
| Acquisition of property and equipment included in accounts payable and accrued liabilities | 3 | 473,000 | 104,000 | 4 | 3 | |
| Finance lease assets obtained in exchange for finance lease liabilities | 3 | — | — | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Personalis, Inc.'s CIK number?
Personalis, Inc.'s SEC CIK number is 0001527753 (1527753). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Personalis, Inc.'s SEC filings?
All of Personalis, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Personalis, Inc. last report earnings?
Personalis, Inc. (PSNL) most recently filed an earnings 8-K with the SEC on May 7, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-211850). This is Personalis, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Personalis, Inc.'s most recent earnings 8-K?
Personalis, Inc.'s latest earnings 8-K (Item 2.02) was filed May 7, 2026 under accession 0001193125-26-211850. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Personalis, Inc.'s latest earnings 8-K →
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