Replimune Group, Inc.
Business
Replimune Group, Inc. is a clinical‑stage biotechnology company developing oncolytic immunotherapies that activate the immune system to treat cancer. It offers proprietary RPx platform product candidates—HSV‑1–based oncolytic viruses including lead candidate RP1 (vusolimogene oderparepvec) and follow‑ons RP2 and RP3—designed to replicate in tumors, induce immunogenic cell death, and deliver immune‑activating payloads alone or in combination with checkpoint inhibitors. Key business areas include clinical development, in‑house viral biologics manufacturing, and strategic collaborations with pharmaceutical partners. The company runs global clinical trials and plans U.S. commercialization while pursuing partnerships and distribution in other regions, with therapies administered by direct tumor injection in outpatient and image‑guided settings.
Summary from filing dated 2025-05-22
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-03-31 | FY 2024 2024-03-31 | FY 2023 2023-03-31 | FY 2022 2022-03-31 | FY 2021 2021-03-31 |
|---|---|---|---|---|---|---|
| Research and development | 189 | 175 | 127 | 80 | 57 | |
| Selling, general and administrative | 72 | 60 | 51 | 39 | 23 | |
| Total operating expenses | 262 | 235 | 177 | 118 | 80 | |
| Loss from operations | −262 | −235 | −177 | −118 | −80 | |
| Research and development incentives | 2 | 2 | 3 | 3 | 3 | |
| Investment income | 21 | 23 | 10 | 390,000 | 916,000 | |
| Interest expense on finance lease liability | −2 | −2 | −2 | −2 | −2 | |
| Interest expense on debt obligations | −6 | −4 | −2 | 0 | −818,000 | |
| Other (expense) income | −202,000 | 771,000 | −6 | −1 | −665,000 | |
| Total other income, net | 15 | 19 | 3 | 278,000 | −915,000 | |
| Loss before income taxes | −247 | −215 | −174 | −118 | — | |
| Income tax provision | 500,000 | 400,000 | 300,000 | 0 | — | |
| Net loss | −247 | −216 | −174 | −118 | −81 | |
| Net loss per common share, basic (in dollars per share) | −3.07 | −3.24 | −2.99 | −2.26 | −1.75 | |
| Net loss per common share, diluted (in dollars per share) | −3.07 | −3.24 | −2.99 | −2.26 | −1.75 | |
| Weighted average common shares outstanding, basic (in shares) | 81 | 67 | 58 | 52 | 46 | |
| Weighted average common shares outstanding, diluted (in shares) | 81 | 67 | 58 | 52 | 46 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-03-31 | FY 2024 2024-03-31 | FY 2023 2023-03-31 | FY 2022 2022-03-31 | FY 2021 2021-10-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 111 | 74 | 147 | 106 | — | |
| Short-term investments | 373 | 346 | 437 | 290 | — | |
| Research and development incentives receivable | 4 | 5 | 3 | 3 | — | |
| Prepaid expenses and other current assets | 8 | 8 | 6 | 5 | — | |
| Total current assets | 496 | 434 | 593 | 404 | — | |
| Property, plant and equipment, net | 14 | 10 | 7 | 8 | — | |
| Restricted cash | 2 | 2 | 2 | 2 | — | |
| Other non-current assets | 1 | 0 | — | — | — | |
| Right-to-use assetoperating leases | 4 | 5 | 5 | 6 | 400,000 | |
| Right-to-use assetfinancing leases | 35 | 37 | 40 | 42 | — | |
| Total assets | 551 | 488 | 647 | 461 | — | |
| Accounts payable | 12 | 3 | 5 | 4 | — | |
| Accrued expenses and other current liabilities | 46 | 34 | 25 | 13 | — | |
| Operating lease liabilities, current | 1 | 1 | 1 | 1 | — | |
| Financing lease liabilities, current | 3 | 3 | 3 | 3 | — | |
| Total current liabilities | 62 | 40 | 34 | 21 | — | |
| Operating lease liabilities, non-current | 3 | 4 | 4 | 5 | — | |
| Financing lease liabilities, non-current | 23 | 23 | 24 | 24 | — | |
| Long term debt, net of discount | 46 | 45 | 29 | 0 | — | |
| Other liabilities, non-current | 941,000 | 786,000 | 472,000 | 0 | — | |
| Total liabilities | 135 | 113 | 91 | 50 | — | |
| Commitments and contingencies (Note 13) | — | — | — | — | — | |
| Common stock, $0.001 par value; 150,000,000 shares authorized as of March 31, 2025 and March 31, 2024; 77,085,024 and 61,415,105 shares issued and outstanding as of March 31, 2025 and March 31, 2024, respectively | 77,000 | 61,000 | 57,000 | 47,000 | — | |
| Additional paid-in capital | 1,359 | 1,071 | 1,035 | 723 | — | |
| Accumulated deficit | −949 | −701 | −485 | −311 | — | |
| Accumulated other comprehensive income | 5 | 5 | 6 | −973,000 | — | |
| Total stockholders equity | 416 | 375 | 555 | 411 | — | |
| Total liabilities and stockholders equity | 551 | 488 | 647 | 461 | — |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-03-31 | FY 2024 2024-03-31 | FY 2023 2023-03-31 | FY 2022 2022-03-31 | FY 2021 2021-03-31 |
|---|---|---|---|---|---|---|
| Net loss | −247 | −216 | −174 | −118 | −81 | |
| Stock-based compensation expense | 35 | 34 | 28 | 24 | 12 | |
| Depreciation and amortization | 4 | 3 | 2 | 2 | 2 | |
| Net amortization of premiums and discounts on short-term investments | −9 | −12 | −6 | 2 | 1 | |
| Noncash interest expense | 2 | 1 | 494,000 | 0 | 181,000 | |
| Unrealized foreign currency transaction losses | −201,000 | −771,000 | 6 | 0 | — | |
| Research and development incentives receivable | 1 | −2 | −61,000 | −247,000 | 325,000 | |
| Prepaid expenses and other current assets | −252,000 | −2 | −1 | −815,000 | −2 | |
| Operating lease, right-of-use-asset | 683,000 | 615,000 | 225,000 | 99,000 | 447,000 | |
| Finance lease, right-of-use-asset | 2 | 2 | 2 | 2 | 2 | |
| Other non-current assets | −1 | 0 | — | — | — | |
| Accounts payable | 10 | −3 | 2 | 1 | −1 | |
| Accrued expenses and other current liabilities | 12 | 9 | 11 | 5 | 3 | |
| Operating lease liabilities | −720,000 | −620,000 | −238,000 | −73,000 | −340,000 | |
| Other non-current liabilities | 155,000 | 314,000 | 472,000 | 0 | — | |
| Net cash used in operating activities | −192 | −185 | −128 | −82 | −61 | |
| Purchases of property, plant and equipment and software capitalization | −7 | −6 | −2 | — | — | |
| Purchase of short-term investments | −404 | −490 | −583 | −256 | −392 | |
| Proceeds from sales and maturities of short-term investments | 386 | 592 | 443 | 256 | 206 | |
| Net cash (used in) provided by investing activities | −24 | 97 | −143 | −2 | −189 | |
| Proceeds from issuance of common stock, net of underwriting fees and offering costs | 156 | 0 | 150 | 0 | 286 | |
| Proceeds from issuance of prefunded warrants to purchase common stock, net of underwriting fees and offering costs | 97 | 0 | 93 | 0 | 92 | |
| Proceeds from long-term debt | 0 | 15 | 28 | 0 | — | |
| Principal payment of finance lease obligation | −599,000 | −476,000 | −365,000 | −264,000 | −145,000 | |
| Proceeds from exercise of stock options | 267,000 | 2 | 3 | 7 | 6 | |
| Net cash provided by financing activities | 252 | 16 | 311 | 7 | 372 | |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | 315,000 | −86,000 | −109,000 | 818,000 | 721,000 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 37 | −72 | 41 | −77 | 123 | |
| Cash paid during the period for interest | 4 | 3 | 1 | 0 | 636,000 | |
| Cash paid for income taxes | 105,000 | 300,000 | 0 | 55,000 | 0 | |
| Purchases of property and equipment included in accounts payable | 171,000 | 101,000 | 103,000 | 415,000 | 98,000 |