Cartesian Therapeutics, Inc.
Business
Cartesian Therapeutics is a late-stage clinical biotechnology company developing mRNA-modified autologous CAR-T cell therapies for autoimmune diseases. The company's lead product candidate, Descartes-08, targets B-cell maturation antigen and is in Phase 3 development for generalized myasthenia gravis, with Phase 2 trials underway in dermatomyositis, antisynthetase syndrome, and juvenile dermatomyositis. Cartesian manufactures its cell therapy candidates in-house in Frederick, Maryland, under cGMP standards, administering personalized, outpatient treatments without preconditioning chemotherapy.
Summary from 10-K filed 2026-03-09
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Collaboration and license | 400,000 | 38 | 26 | 111 | 85 | |
| Grant | 2 | 638,000 | 0 | — | — | |
| Total revenues | 3 | 39 | 26 | — | — | |
| Research and development | 58 | 45 | 71 | 72 | 69 | |
| General and administrative | 31 | 30 | 40 | 24 | 21 | |
| Impairment of indefinite-lived intangible and long-lived assets | 57 | 8 | — | — | — | |
| Total operating expenses | 146 | 83 | 112 | 96 | 90 | |
| Operating loss | −143 | −44 | −86 | 15 | −5 | |
| Interest income | 7 | 7 | 5 | — | — | |
| Gain on change in fair value of warrant liabilities | 4 | 3 | 13 | 21 | −2 | |
| Loss on change in fair value of contingent value right liability | −4 | −37 | −18 | 0 | 0 | |
| Loss on change in fair value of forward contract liabilities | 0 | −7 | −150 | 0 | 0 | |
| Other (expense) income, net | −2 | 606,000 | 691,000 | 330,000 | 15,000 | |
| Total other income (expense), net | 4 | −33 | — | — | — | |
| Loss before income taxes | −139 | −77 | −239 | 35 | −10 | |
| Income tax benefit (expense) | 9 | −300,000 | 19 | 609,000 | −16 | |
| Net loss | −130 | −77 | −220 | 35 | −26 | |
| Foreign currency translation adjustment | 45,000 | −21,000 | −53,000 | 18,000 | −2,000 | |
| Total comprehensive loss | −130 | −77 | −220 | 35 | −26 | |
| Basic (in dollars per share) | −5.02 | −4.48 | −49.76 | 0.24 | −0.22 | |
| Diluted (in dollars per share) | −5.02 | −4.49 | −49.76 | 0.1 | −0.22 | |
| Basic (in shares) | 26 | 17 | 5 | 145 | 114 | |
| Diluted (in shares) | 26 | 17 | 5 | 146 | 114 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 125 | 213 | 77 | 106 | 114 | |
| Accounts receivable | 1 | 872,000 | 6 | 7 | 10 | |
| Prepaid expenses and other current assets | 3 | 3 | 5 | 4 | 6 | |
| Total current assets | 129 | 217 | 91 | 148 | 144 | |
| Property and equipment, net | 12 | 10 | 2 | 3 | 2 | |
| Right-of-use assets, net | 6 | 6 | 10 | 12 | 10 | |
| In-process research and development assets | 94 | 151 | 151 | 0 | — | |
| Goodwill | 48 | 48 | 48 | 0 | — | |
| Long-term restricted cash | 2 | 2 | 1 | 1 | 1 | |
| Investment | 0 | 2 | 2 | 2 | 2 | |
| Long-term prepaid expenses and other assets | 6 | 518,000 | — | — | — | |
| Total assets | 296 | 435 | 305 | 166 | 160 | |
| Accounts payable | 1 | 288,000 | 3 | 316,000 | 224,000 | |
| Accrued expenses and other current liabilities | 9 | 12 | 16 | 14 | — | |
| Lease liabilities | 4 | 3 | 2 | 2 | 1 | |
| Contingent value right liability | 0 | 8 | 16 | 0 | — | |
| Total current liabilities | 15 | 23 | 68 | 25 | 72 | |
| Lease liabilities, net of current portion | 9 | 11 | 9 | 10 | 9 | |
| Warrant liability | 141,000 | 4 | 6 | 19 | — | |
| Contingent value right liability, net of current portion | 392 | 388 | 343 | 0 | — | |
| Deferred tax liabilities, net | 7 | 16 | 16 | 0 | — | |
| Total liabilities | 423 | 442 | 445 | 72 | 137 | |
| Commitments and contingencies (Note 18) | — | — | — | — | — | |
| Preferred stock, value, issued | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value; 350,000,000 shares authorized as of December 31, 2025 and 2024; 26,011,106 and 25,767,369 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 3,000 | 3,000 | 1,000 | 15,000 | 12,000 | |
| Additional paid-in capital | 701 | 690 | 179 | 493 | 457 | |
| Accumulated deficit | −822 | −692 | −615 | −395 | −430 | |
| Accumulated other comprehensive loss | −5 | −5 | −5 | −5 | −5 | |
| Total stockholders deficit | −126 | −7 | −440 | 94 | 23 | |
| Total liabilities and stockholders deficit | 296 | 435 | 305 | 166 | 160 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 3 | 1 | 843,000 | 1 | 1 | |
| Non-cash lease expense | 778,000 | 2 | 2 | 1 | 1 | |
| Loss on disposal of property and equipment | 0 | 273,000 | 477,000 | −147,000 | 0 | |
| Stock-based compensation expense | 11 | 7 | 23 | 11 | 8 | |
| Loss on change in fair value of forward contract liabilities | 0 | 7 | — | — | — | |
| Loss on impairment of investment | 2 | 0 | — | — | — | |
| (Benefit) provision for deferred taxes | −9 | 287,000 | −19 | 0 | 0 | |
| Accounts receivable | −243,000 | 5 | 726,000 | 3 | −3 | |
| Unbilled receivable | 0 | 3 | 181,000 | −3 | 0 | |
| Prepaid expenses and other assets | −5 | 2 | −1 | 2 | −1 | |
| Accounts payable | 1 | −3 | 3 | 92,000 | −219,000 | |
| Deferred revenue | 0 | −6 | 5 | −65 | −45 | |
| Accrued expenses and other liabilities | −4 | −7 | −3 | 2 | 1 | |
| Net cash used in operating activities | −74 | −24 | −51 | −32 | −60 | |
| Purchases of property and equipment | −5 | −9 | −206,000 | −1 | −1 | |
| Proceeds from the sale of property and equipment | 0 | 351,000 | 0 | 0 | 0 | |
| Net cash used in investing activities | −5 | −9 | 35 | −15 | −17 | |
| Proceeds from issuance of Series A Preferred Stock, gross in private placement | 0 | 40 | 20 | 0 | 0 | |
| Net proceeds from issuance of common stock and Series B Preferred Stock in private placement | 0 | 124 | — | 0 | 0 | |
| Equity offering costs | −624,000 | −66,000 | 0 | — | — | |
| Proceeds from exercise of common warrants | 0 | 3 | 0 | 0 | 0 | |
| Proceeds from exercise of stock options | 323,000 | 1 | 0 | 156,000 | 778,000 | |
| Distribution of Contingent Value Rights | −8 | 0 | — | — | — | |
| Net cash (used in) provided by financing activities | −8 | 168 | −13 | 39 | 53 | |
| Effect of exchange rate changes on cash | 45,000 | −21,000 | −53,000 | 20,000 | −3,000 | |
| Net change in cash, cash equivalents, and restricted cash | −87 | 136 | −30 | −7 | −25 | |
| Purchase of property and equipment not yet paid | 18,000 | 847,000 | 128,000 | 17,000 | 224,000 | |
| Equity offering costs in accrued liabilities | 30,000 | 451,000 | 0 | — | 24,000 | |
| Operating lease right-of-use assets obtained in exchange for operating lease liabilities | 844,000 | 5 | — | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Cartesian Therapeutics, Inc.'s CIK number?
Cartesian Therapeutics, Inc.'s SEC CIK number is 0001453687 (1453687). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Cartesian Therapeutics, Inc.'s SEC filings?
All of Cartesian Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Cartesian Therapeutics, Inc. last report earnings?
Cartesian Therapeutics, Inc. (RNAC) most recently filed an earnings 8-K with the SEC on Apr 30, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001453687-26-000081). This is Cartesian Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Cartesian Therapeutics, Inc.'s most recent earnings 8-K?
Cartesian Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed Apr 30, 2026 under accession 0001453687-26-000081. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Cartesian Therapeutics, Inc.'s latest earnings 8-K →
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