Revolution Medicines, Inc.
Business
Revolution Medicines is a clinical-stage precision oncology company developing novel targeted therapies for RAS-addicted cancers using proprietary small-molecule inhibitors. The company's pipeline comprises RAS(ON) Inhibitors—direct inhibitors of the active form of RAS proteins—designed as monotherapies, combination regimens with other RAS(ON) Inhibitors, or partnered with standard-of-care therapies, across pancreatic cancer, non-small cell lung cancer, and colorectal cancer indications. The company is advancing multiple clinical programs including daraxonrasib (multi-selective), zoldonrasib (G12D-selective), elironrasib (G12C-selective), and RMC-5127 (G12V-selective), with regulatory designations including Breakthrough Therapy Designation for multiple candidates and orphan drug designation for pancreatic cancer applications.
Summary from 10-K filed 2026-02-25
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 0 | 0 | 12 | 35 | 29 | |
| Research and development | 987 | 592 | 423 | 253 | 187 | |
| General and administrative | 195 | 97 | 76 | 41 | 30 | |
| Total operating expenses | 1,182 | 690 | 499 | 294 | 217 | |
| Loss from operations | −1,182 | −690 | −487 | −258 | −188 | |
| Interest income | 91 | 87 | 47 | 9 | 929,000 | |
| Interest expense | −24 | 0 | 0 | — | — | |
| Change in fair value of warrant liability and contingent earn-out shares | −15 | 4 | 115,000 | 0 | 0 | |
| Other expense, net: | −37,000 | −3 | −303,000 | 0 | −12,000 | |
| Total non-operating income, net | 51 | 89 | 47 | 9 | 917,000 | |
| Income (loss) before provision for income taxes | −1,131 | −601 | −440 | −249 | −187 | |
| Benefit from income taxes | 0 | 800,000 | 4 | 400,000 | 0 | |
| Net loss | −1,131 | −600 | −436 | −249 | −187 | |
| Net loss per share attributable to common stockholders, basic | −5.95 | −3.58 | −3.86 | −3.08 | −2.57 | |
| Net loss per share attributable to common stockholders, diluted | −5.95 | −3.58 | −3.86 | −3.08 | −2.57 | |
| Weighted-average common shares used to compute net loss per share, basic | 190 | 168 | 113 | 81 | 73 | |
| Weighted-average common shares used to compute net loss per share, diluted | 190 | 168 | 113 | 81 | 73 | |
| Unrealized gain on investments, net | 2 | 777,000 | 2 | 2 | −492,000 | |
| Comprehensive loss | −1,129 | −599 | −434 | −250 | −188 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 384 | 543 | 696 | 161 | 108 | |
| Marketable securities | 1,642 | 1,746 | 1,157 | 484 | 469 | |
| Prepaid expenses and other current assets | 49 | 38 | 25 | 11 | 7 | |
| Total current assets | 2,075 | 2,328 | 1,879 | 660 | 590 | |
| Property and equipment, net | 33 | 24 | 23 | 19 | 12 | |
| Operating lease right-of-use asset | 132 | 118 | 77 | 55 | 60 | |
| Intangible assets, net | 56 | 57 | 58 | 59 | 60 | |
| Goodwill | 15 | 15 | 15 | 15 | 15 | |
| Restricted cash | 5 | 4 | 3 | 2 | 2 | |
| Long-term deposits | 24 | 12 | — | — | — | |
| Other noncurrent assets | 15 | 2 | 7 | 3 | 758,000 | |
| Total assets | 2,355 | 2,558 | 2,062 | 812 | 738 | |
| Accounts payable | 65 | 54 | 62 | 21 | 14 | |
| Accrued expenses and other current liabilities | 209 | 97 | 75 | 29 | 28 | |
| Operating lease liability, current | 16 | 13 | 7 | 7 | 6 | |
| Total current liabilities | 290 | 164 | 144 | 62 | 60 | |
| Deferred tax liability | 2 | 2 | 3 | 7 | 7 | |
| Operating lease liability, noncurrent | 142 | 123 | 81 | 57 | 60 | |
| Liability related to the sale of future royalties | 268 | 0 | — | — | — | |
| Warrant liability | 19 | 3 | 7 | 0 | — | |
| Other noncurrent liabilities | 1 | 670,000 | 1 | 301,000 | 634,000 | |
| Total liabilities | 723 | 293 | 236 | 127 | 135 | |
| Commitments and contingencies (Note 8) | — | — | — | — | — | |
| Preferred stock, $0.0001 par value; 10,000,000 shares authorized at December 31, 2025 and December 31, 2024, respectively; none issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value; 300,000,000 shares authorized as of December 31, 2025 and December 31, 2024, respectively; 197,001,401 and 185,896,625 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively | 19,000 | 18,000 | 16,000 | 9,000 | 8,000 | |
| Additional paid-in capital | 4,497 | 4,002 | 2,963 | 1,388 | 1,056 | |
| Accumulated other comprehensive income | 3 | 1 | 544,000 | −2 | −376,000 | |
| Accumulated deficit | −2,900 | −1,738 | −1,138 | −701 | −453 | |
| Total stockholders' equity | 1,631 | 2,265 | 1,826 | 685 | 603 | |
| Total liabilities and stockholders' equity | 2,355 | 2,558 | 2,062 | 812 | 738 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −1,131 | −600 | −436 | −249 | −187 | |
| Loss on disposal of fixed assets | 32,000 | 118,000 | 52,000 | 19,000 | 119,000 | |
| Amortization of intangible assets | 900,000 | 1 | 1 | 1 | 1 | |
| Stock-based compensation expense | 118 | 79 | 62 | 31 | 21 | |
| Depreciation and amortization | 8 | 7 | 5 | 4 | — | |
| Change in fair value of warrant liability and contingent earn-out shares | 15 | −4 | 115,000 | 0 | 0 | |
| Non-cash interest expense on liabilities related to sale of future royalties | 24 | 0 | 0 | — | — | |
| Net amortization of premium or discount on marketable securities | −28 | −45 | −22 | −3 | 3 | |
| Amortization of operating lease right-of-use asset | 8 | 4 | 3 | 5 | 3 | |
| Accounts receivable | 0 | 1 | 3 | 1 | 464,000 | |
| Prepaid expenses and other current assets | −10 | −10 | −3 | −4 | 198,000 | |
| Accounts payable | 10 | −6 | 32 | 7 | 2 | |
| Accrued expenses and other current liabilities | 112 | 22 | 15 | 2 | 9 | |
| Deferred revenue | 0 | 0 | −4 | −14 | −2 | |
| Operating lease liability | −957,000 | −245,000 | −2 | −2 | −1 | |
| Deferred tax liability | 0 | −762,000 | −4 | −419,000 | 0 | |
| Long-term deposits | −12 | −8 | −2 | — | — | |
| Other noncurrent assets | −13 | 2 | 870,000 | −2 | 81,000 | |
| Other noncurrent liabilities | 537,000 | 212,000 | 157,000 | −190,000 | 151,000 | |
| Net cash used in operating activities | −898 | −557 | −351 | −224 | −147 | |
| Purchases of marketable securities | −1,795 | −2,137 | −1,059 | −613 | −671 | |
| Maturities of marketable securities | 1,923 | 1,593 | 724 | 599 | 527 | |
| Sales of marketable securities | 6 | 0 | 0 | — | — | |
| Purchases of property and equipment | −16 | −10 | −8 | −11 | −7 | |
| Net cash provided by (used in) investing activities | 118 | −554 | −343 | −24 | −142 | |
| Cash, cash equivalents and restricted cash acquired in connection with EQRx Acquisition, net of transaction costs | 0 | 0 | 841 | 0 | 0 | |
| Proceeds from the sale of future royalties, net of issuance costs | 244 | 0 | 0 | — | — | |
| Proceeds from issuance of common stock, net of issuance costs | 0 | 728 | 324 | 248 | 281 | |
| Proceeds from issuance of common stock from at-the-market offering, net of transaction costs | 348 | 119 | 62 | 50 | 10 | |
| Proceeds from issuance of common stock pursuant to stock option exercises | 21 | 12 | 3 | — | — | |
| Proceeds from issuance of common stock related to employee stock purchase plan | 8 | 5 | 3 | 2 | 2 | |
| Tax payment for common stock withheld in satisfaction of withholding tax requirements | 0 | 0 | −4 | 0 | 0 | |
| Exercise of warrants | 4,000 | 0 | 0 | — | — | |
| Payments of deferred offering costs | 220,000 | 284,000 | 0 | 42,000 | −424,000 | |
| Net cash provided by financing activities | 622 | 959 | 1,229 | 301 | 294 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | −158 | −152 | 536 | 53 | 5 | |
| Issuance of common stock for EQRx acquisition | 0 | 0 | 1,086 | 0 | 0 | |
| Fair value of net assets acquired in connection with EQRx Acquisition | 0 | 0 | 291 | 0 | 0 | |
| Purchases of property and equipment in accounts payable and accrued expenses and other current liabilities | 2 | 2 | 3 | 1 | 1 | |
| Right-of-use assets obtained in exchange for operating lease liabilities | 22 | 45 | 25 | 0 | 35 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Revolution Medicines, Inc.'s CIK number?
Revolution Medicines, Inc.'s SEC CIK number is 0001628171 (1628171). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Revolution Medicines, Inc.'s SEC filings?
All of Revolution Medicines, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Revolution Medicines, Inc. last report earnings?
Revolution Medicines, Inc. (RVMD) most recently filed an earnings 8-K with the SEC on May 6, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-208918). This is Revolution Medicines, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Revolution Medicines, Inc.'s most recent earnings 8-K?
Revolution Medicines, Inc.'s latest earnings 8-K (Item 2.02) was filed May 6, 2026 under accession 0001193125-26-208918. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Revolution Medicines, Inc.'s latest earnings 8-K →
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