SAB Biotherapeutics, Inc.
Business
SAB Biotherapeutics is a clinical-stage biopharmaceutical company developing multi-specific, fully human immunoglobulin G (hIgG) antibodies to treat autoimmune and immune disorders. The company's lead candidate, SAB-142, is a human anti-thymocyte globulin targeting type 1 diabetes, currently in Phase 2b clinical trials (SAFEGUARD study). SAB Biotherapeutics uses proprietary transchromosomic cattle (Tc-Bovine) technology to produce human immunoglobulins without human plasma donors, enabling large-scale manufacturing of targeted, polyclonal antibodies. The company operates manufacturing and research facilities in Sioux Falls, South Dakota, and conducts global clinical development.
Summary from 10-K filed 2026-03-09
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 0 | 1 | 2 | 24 | 61 | |
| Research and development | 34 | 30 | 17 | 36 | 57 | |
| General and administrative | 15 | 14 | 24 | 16 | 17 | |
| Total operating expenses | 49 | 44 | 40 | 53 | 74 | |
| Loss from operations | −49 | −43 | −38 | −29 | −13 | |
| Changes in fair value of warrant liabilities | 63 | 5 | −5 | 10 | −4 | |
| Interest expense | −240,664 | −318,401 | −315,284 | — | — | |
| Interest income | 1 | 1 | 584,966 | 71,072 | 23,115 | |
| Other income | 3 | 2 | 435,089 | 33,754 | — | |
| Warrant issuance expense | −5 | 0 | — | — | — | |
| Total other income | 62 | 9 | −4 | 10 | −4 | |
| Net income (loss) | 13 | −34 | −42 | −19 | −17 | |
| Unrealized gain, change in fair value of available-for-sale securities, net of tax | 185,464 | 647 | — | — | — | |
| Foreign currency translation gain (loss) | 136,456 | −162,477 | 26,420 | — | — | |
| Total comprehensive income (loss) | 14 | −34 | −42 | −19 | — | |
| Basic income (loss) per common share | 0.22 | −3.68 | −7.64 | −4.31 | −0.63 | |
| Diluted loss per common share | −0.79 | −3.68 | −7.64 | −4.31 | −0.63 | |
| Weighted-average common shares outstanding - basic | 19 | 9 | 6 | 4 | 27 | |
| Weighted-average common shares outstanding - diluted | 61 | 9 | 6 | 4 | 27 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2022 2022-06-30 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 11 | 9 | 57 | 15 | 17 | |
| Short-term investments | 86 | 12 | 0 | — | — | |
| Accrued interest receivable | 900,000 | 100,000 | 0 | — | — | |
| Prepaid expenses and other current assets | 4 | 3 | 2 | 1 | — | |
| Total current assets | 101 | 24 | 59 | 22 | 28 | |
| Deferred issuance cost | 200,000 | 300,000 | 0 | — | — | |
| Long-term prepaid assets | 5 | 220,997 | 350,230 | 467,694 | 535,082 | |
| Long-term investments | 47 | — | — | — | — | |
| Operating lease right-of-use assets | 3 | 970,294 | 1 | 1 | 2 | |
| Financing lease right-of-use assets | 3 | 4 | 4 | 4 | 4 | |
| Property, plant and equipment, net | 13 | 15 | 20 | 23 | 25 | |
| Total assets | 173 | 44 | 84 | 51 | 59 | |
| Accounts payable | 3 | 2 | 945,927 | 4 | 5 | |
| Notes payable | 0 | 275,849 | 1 | 772,665 | 278,441 | |
| Accrued expenses and other current liabilities | 7 | 5 | 7 | 10 | 10 | |
| Operating lease liabilities, current portion | 797,402 | 393,430 | 669,946 | 490,794 | 1 | |
| Finance lease liabilities, current portion | 153,967 | 142,563 | 132,004 | 132,788 | 140,767 | |
| Total current liabilities | 11 | 8 | 11 | 15 | 16 | |
| Operating lease liabilities, noncurrent | 2 | 581,148 | 635,777 | 361,225 | 1 | |
| Finance lease liabilities, noncurrent | 3 | 3 | 3 | 4 | 4 | |
| Warrant liabilities | 6 | 6 | 12 | 320,930 | 1 | |
| Total liabilities | 21 | 18 | 27 | 20 | 22 | |
| Commitments and contingencies (Note 18) | — | — | — | — | — | |
| Common stock; $0.0001 par value; 800,000,000 shares authorized at December 31, 2025 and December 31, 2024; 47,664,564 and 9,343,533 shares issued at December 31, 2025 and December 31, 2024, respectively, and 47,609,899 and 9,288,868 outstanding at December 31, 2025 and December 31, 2024, respectively | 4,766 | 935 | 929 | 510 | 4,358 | |
| Treasury stock, at cost; 54,665 shares held at December 31, 2025 and December 31, 2024, respectively | −6 | −6 | −6 | −6 | −6 | |
| Additional paid-in capital | 268 | 156 | 153 | 84 | 76 | |
| Accumulated other comprehensive income (loss) | 186,510 | −135,410 | 26,420 | — | — | |
| Accumulated deficit | −111 | −124 | −90 | −48 | −33 | |
| Total stockholders' equity | 151 | 26 | 57 | 31 | 37 | |
| Total liabilities and stockholders' equity | 173 | 44 | 84 | 51 | 59 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 3 | 5 | 4 | 3 | 1 | |
| Amortization of finance right-of-use assets | 100,000 | 100,000 | 100,000 | 100,000 | — | |
| Stock-based compensation expense | 5 | 3 | 2 | 3 | 2 | |
| Net realized and unrealized gain on investment in short-term securities | −73,967 | — | — | — | — | |
| Accretion of discounts on short-term investments | −88,631 | −237,093 | — | — | — | |
| Write-off of deferred issuance costs | 261,105 | — | — | — | — | |
| Accrued interest receivable | −891,826 | −54,955 | — | — | — | |
| Prepaid expenses and other current assets | −5 | −590,461 | −523,610 | — | — | |
| Operating lease right-of-use assets and liabilities, net | 67,420 | −23,458 | 387,299 | — | — | |
| Accounts payable | 1 | 923,323 | −3 | −779,425 | −3 | |
| Deferred grant income | — | −1 | 1 | −100,000 | 0 | |
| Accrued expense and other current liabilities | 941,524 | −1 | −2 | −3 | 3 | |
| Net cash used in operating activities | −45 | −34 | −25 | −23 | 2 | |
| Proceeds from the sale of equipment | 500 | — | 44,450 | 76,390 | 0 | |
| Purchases of equipment | −933,156 | −337,262 | −197,154 | −2 | −11 | |
| Purchases of investment securities | −142 | −37 | — | — | — | |
| Sales and maturities of investments | 21 | 26 | — | — | — | |
| Net cash used in investing activities | −122 | −12 | −152,704 | −2 | −11 | |
| Proceeds from the 2025 PIPE, net of Series B issuance costs | 169 | — | — | — | — | |
| Payment of deferred issuance costs | −758 | −261,105 | — | — | — | |
| Proceeds from issuance of notes payable | — | 515,986 | 765,194 | 1 | −3 | |
| Principal payments of notes payable | −275,849 | −1 | −1 | −2 | −1 | |
| Principal payments on finance leases | −142,563 | −132,003 | −126,985 | −161,055 | −203,124 | |
| Proceeds from exercise of stock options | — | 20,409 | 9,582 | 76,971 | 6,750 | |
| Tax payments for share settlement of restricted stock units | −11,205 | −24,931 | — | — | — | |
| Net cash provided by (used in) financing activities | 168 | −1 | 67 | 1 | 36 | |
| Effect of exchange rate changes on cash and cash equivalents | −213,497 | −241,198 | 18,144 | — | — | |
| Net increase (decrease) in cash and cash equivalents | 2 | −48 | 42 | −24 | 27 | |
| Cash paid for interest | 242,032 | 373,954 | 245,481 | 293,392 | 294,459 | |
| Right-of-use assets obtained in exchange for operating lease liabilities | 2 | 368,425 | 993,811 | 65,088 | 505,187 | |
| Deferred issuance costs included in accrued expenses | 149,387 | — | — | — | — | |
| Reclassification of warrants from liability to equity | 91 | — | — | — | — | |
| Reclassification of Redeemable Preferred Stock to Permanent Equity upon Requisite Approval | 16 | — | — | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is SAB Biotherapeutics, Inc.'s CIK number?
SAB Biotherapeutics, Inc.'s SEC CIK number is 0001833214 (1833214). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find SAB Biotherapeutics, Inc.'s SEC filings?
All of SAB Biotherapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did SAB Biotherapeutics, Inc. last report earnings?
SAB Biotherapeutics, Inc. (SABS) most recently filed an earnings 8-K with the SEC on Mar 29, 2024, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0000950170-24-038429). This is SAB Biotherapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is SAB Biotherapeutics, Inc.'s most recent earnings 8-K?
SAB Biotherapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed Mar 29, 2024 under accession 0000950170-24-038429. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View SAB Biotherapeutics, Inc.'s latest earnings 8-K →
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