Tango Therapeutics, Inc.
Business
Tango Therapeutics is a clinical-stage biopharmaceutical company discovering and developing targeted oncology therapies designed to exploit synthetic lethality in cancers with specific genetic alterations. The company is advancing two MTA-cooperative PRMT5 inhibitors—vopimetostat for non-CNS cancers and TNG456, a brain-penetrant variant, for CNS cancers including glioblastoma—along with a CoREST inhibitor (TNG260) and HBS1L degrader (TNG961) in development. Tango operates as a clinical-stage developer relying on third-party contract manufacturing and conducting trials across multiple oncology indications in the United States and European Economic Area.
Summary from 10-K filed 2026-03-05
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total Revenue | 62 | 42 | 37 | 25 | 37 | |
| Research and development | 132 | 144 | 115 | 106 | 78 | |
| General and administrative | 42 | 44 | 36 | 30 | 18 | |
| Total operating expenses | 174 | 188 | 151 | 136 | 95 | |
| Loss from operations | −111 | −146 | −114 | −111 | −58 | |
| Interest income | 6 | 8 | 7 | 1 | 495,000 | |
| Other income, net | 4 | 8 | 6 | 1 | −248,000 | |
| Total other income, net | 10 | 16 | 13 | 3 | 247,000 | |
| Loss before income taxes | −102 | −130 | −102 | −108 | −58 | |
| Provision for income taxes | −4,000 | −200,000 | −100,000 | −100,000 | −300,000 | |
| Net loss | −102 | −130 | −102 | −108 | −58 | |
| Net loss per common share - basic | −0.87 | −1.19 | −1.08 | −1.23 | −0.94 | |
| Net loss per common share - diluted | −0.87 | −1.19 | −1.08 | −1.23 | −0.94 | |
| Weighted average number of common shares outstanding - basic | 116 | 109 | 95 | 88 | 62 | |
| Weighted average number of common shares outstanding - diluted | 116 | 109 | 95 | 88 | 62 | |
| Unrealized (loss) gain on marketable securities | −112,000 | 150,000 | 4 | −3 | −782,000 | |
| Comprehensive loss | −102 | −130 | −98 | −111 | −59 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 112 | 70 | 66 | 60 | 143 | |
| Marketable securities | 231 | 188 | 271 | 306 | 343 | |
| Restricted cash | 400,000 | 900,000 | 900,000 | 567,000 | 567,000 | |
| Prepaid expenses and other current assets | 10 | 8 | 9 | 7 | 5 | |
| Total current assets | 354 | 266 | 347 | 375 | 492 | |
| Property and equipment, net | 7 | 8 | 10 | 11 | 5 | |
| Operating lease right-of-use assets | 36 | 40 | 44 | 47 | 1 | |
| Restricted cash, net of current portion | 2 | 3 | 3 | 3 | 2 | |
| Other assets | 303,000 | 4,000 | 46,000 | 5,000 | 19,000 | |
| Total assets | 399 | 316 | 403 | 436 | 500 | |
| Accounts payable | 1 | 2 | 3 | 4 | 3 | |
| Accrued expenses and other current liabilities | 18 | 16 | 15 | 17 | 10 | |
| Operating lease liabilities | 3 | 2 | 2 | 2 | 2 | |
| Deferred revenue | 0 | 18 | 26 | 32 | 26 | |
| Total current liabilities | 22 | 38 | 46 | 56 | 41 | |
| Operating lease liabilities, net of current portion | 31 | 34 | 37 | 39 | — | |
| Deferred revenue, net of current portion | 0 | 45 | 67 | 92 | 115 | |
| Total liabilities | 53 | 117 | 149 | 187 | 155 | |
| Commitments and contingencies (Note 8) | — | — | — | — | — | |
| Preferred stock, $0.001 par value; 10,000,000 shares authorized; no shares issued and outstanding as of December 31, 2025 and 2024, respectively | — | — | — | — | — | |
| Common stock, $0.001 par value; 400,000,000 and 200,000,000 shares authorized at December 31, 2025 and December 31, 2024, respectively; 135,940,454 and 107,729,343 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 136,000 | 108,000 | 102,000 | 88,000 | 88,000 | |
| Additional paid-in capital | 949 | 701 | 624 | 523 | 507 | |
| Accumulated other comprehensive income | 224,000 | 336,000 | 186,000 | −4 | −765,000 | |
| Accumulated deficit | −603 | −502 | −371 | −270 | −161 | |
| Total stockholders' equity | 346 | 200 | 253 | 249 | 345 | |
| Total liabilities and stockholders' equity | 399 | 316 | 403 | 436 | 500 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −102 | −130 | −102 | — | — | |
| Depreciation | 2 | 3 | 2 | 2 | 900,000 | |
| Noncash operating lease expense | 4 | 4 | 4 | 2 | 1 | |
| Stock-based compensation | 26 | 29 | 19 | 14 | 8 | |
| Accretion on marketable securities | −3 | −5 | −3 | — | — | |
| Other, net | −77,000 | 23,000 | 22,000 | −669,000 | 254,000 | |
| Accounts receivable | — | — | 2 | — | — | |
| Prepaid expenses and other current assets | −2 | 370,000 | −2 | −2 | −3 | |
| Other long-term assets | −299,000 | 43,000 | −41,000 | 122,000 | −139,000 | |
| Accounts payable | −825,000 | −1 | −2 | 1 | 1 | |
| Accrued expenses and other liabilities | 1 | 1 | −2 | 8 | 4 | |
| Operating lease liabilities | −3 | −2 | −2 | 2 | −1 | |
| Deferred revenue | −62 | −30 | −32 | −17 | −12 | |
| Net cash used in operating activities | −139 | −132 | −118 | −109 | −60 | |
| Purchase of property and equipment | −1 | −754,000 | −2 | −8 | −2 | |
| Sales and maturities of marketable securities | 225 | 328 | 354 | 243 | 191 | |
| Purchases of marketable securities | −264 | −241 | −311 | −209 | −372 | |
| Net cash (used in) provided by investing activities | −41 | 86 | 41 | 26 | −183 | |
| Proceeds from issuance of common stock and pre-funded warrants | 212 | 42 | 80 | — | — | |
| Proceeds from issuance of common stock upon exercise of stock options and purchase of shares under ESPP | 10 | 6 | 2 | 2 | 1 | |
| Return of capital from a stockholder - related party | — | — | 689,000 | — | — | |
| Payment of transaction costs | −36,000 | — | −241,000 | −8,000 | — | |
| Net cash provided by financing activities | 223 | 48 | 82 | 2 | 357 | |
| Net change in cash, cash equivalents and restricted cash | 43 | 2 | 6 | −81 | 114 | |
| Cash paid for leases | 6 | 6 | 6 | 1 | 2 | |
| Purchases of property and equipment included in accounts payable and accrued expenses | — | — | 38,000 | 131,000 | 154,000 | |
| Operating lease liabilities from obtaining right-of-use assets | 1 | 210,000 | — | 48 | — | |
| Revaluation of right-of-use asset and lease liability upon lease remeasurement | 1 | 497,000 | −228,000 | 300,000 | 5 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Tango Therapeutics, Inc.'s CIK number?
Tango Therapeutics, Inc.'s SEC CIK number is 0001819133 (1819133). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Tango Therapeutics, Inc.'s SEC filings?
All of Tango Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Tango Therapeutics, Inc. last report earnings?
Tango Therapeutics, Inc. (TNGX) most recently filed an earnings 8-K with the SEC on May 13, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-221677). This is Tango Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Tango Therapeutics, Inc.'s most recent earnings 8-K?
Tango Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 13, 2026 under accession 0001193125-26-221677. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Tango Therapeutics, Inc.'s latest earnings 8-K →
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