Tenaya Therapeutics, Inc.
Business
Tenaya Therapeutics is a clinical-stage biotechnology company developing precision medicines for genetic heart disease. Its lead programs are AAV9-based gene therapies TN-201 for MYBPC3-associated hypertrophic cardiomyopathy and TN-401 for PKP2-associated arrhythmogenic right ventricular cardiomyopathy, both in Phase 1b/2 trials, plus TN-301, a selective HDAC6 inhibitor small molecule in Phase 1 development for heart failure with preserved ejection fraction. Tenaya operates as a fully integrated biopharmaceutical company with proprietary capabilities in target discovery, capsid engineering, promoter design, and AAV manufacturing.
Summary from 10-K filed 2026-03-11
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 69 | 87 | 98 | 95 | 54 | |
| General and administrative | 25 | 29 | 33 | 31 | 18 | |
| Total operating expenses | 93 | 116 | 131 | 126 | 73 | |
| Loss from operations | −93 | −116 | −131 | −126 | −73 | |
| Interest income | 3 | 5 | 7 | 2 | 108,000 | |
| Other income, net | 52,000 | 82,000 | 53,000 | 2,000 | −23,000 | |
| Total other income, net | 3 | 5 | 7 | 2 | 85,000 | |
| Net loss before income tax expense | −91 | −111 | −124 | −124 | −73 | |
| Net loss | −91 | −111 | −124 | −124 | −73 | |
| Net unrealized (loss) gain on marketable securities | −28,000 | 134,000 | 272,000 | −237,000 | −141,000 | |
| Comprehensive loss | −91 | −111 | −124 | −124 | −73 | |
| Net loss per share, basic | −0.59 | −1.31 | −1.68 | −2.76 | −4.1 | |
| Net loss per share, diluted | −0.59 | −1.31 | −1.68 | −2.76 | −4.1 | |
| Weighted-average shares used in computing net loss per share, basic | 153 | 85 | 74 | 45 | 18 | |
| Weighted-average shares used in computing net loss per share, diluted | 153 | 85 | 74 | 45 | 18 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 101 | 4 | 46 | 95 | 38 | |
| Short-term investments in marketable securities | — | 57 | 59 | 91 | 213 | |
| Prepaid expenses and other current assets | 5 | 6 | 7 | 7 | 4 | |
| Total current assets | 106 | 67 | 112 | 194 | 255 | |
| Property and equipment, net | 28 | 36 | 43 | 51 | 43 | |
| Operating lease right-of-use assets | 9 | 12 | 10 | 12 | 12 | |
| Other noncurrent assets | 4 | 5 | 6 | 5 | 4 | |
| Total assets | 147 | 120 | 171 | 279 | 314 | |
| Accounts payable | 4 | 5 | 6 | 10 | 11 | |
| Accrued and other current liabilities | 9 | 8 | 13 | 11 | 9 | |
| Operating lease liabilities, current | 3 | 3 | 4 | 4 | 2 | |
| Total current liabilities | 15 | 16 | 23 | 24 | 22 | |
| Operating lease liabilities, noncurrent | 8 | 11 | 8 | 11 | 14 | |
| Other noncurrent liabilities | 410,000 | 281,000 | 253,000 | 228,000 | 182,000 | |
| Total liabilities | 24 | 27 | 31 | 36 | 36 | |
| Commitments and contingencies (Note 4) | — | — | — | — | — | |
| Preferred stock, $0.0001 par value; 200,000,000 shares authorized as of December 31, 2025 and 2024; no shares issued and outstanding as of December 31, 2025 and 2024 | — | — | — | — | — | |
| Common stock, $0.0001 par value; 1,000,000,000 shares authorized as of December 31, 2025 and 2024; 216,760,283 and 86,542,340 shares issued and outstanding as of December 31, 2025 and 2024 | 21,000 | 8,000 | 7,000 | 7,000 | 4,000 | |
| Additional paid-in capital | 728 | 607 | 543 | 523 | 434 | |
| Accumulated other comprehensive income | 0 | 28,000 | −106,000 | −378,000 | −141,000 | |
| Accumulated deficit | −605 | −514 | −403 | −279 | −156 | |
| Total stockholders' equity | 123 | 93 | 139 | 243 | 279 | |
| Total liabilities and stockholders' equity | 147 | 120 | 171 | 279 | 314 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −91 | −111 | −124 | −124 | −73 | |
| Depreciation and amortization | 8 | 8 | 9 | 6 | 3 | |
| Amortization (accretion) of premium (discount) on marketable securities | 411,000 | −184,000 | 315,000 | −307,000 | 131,000 | |
| Stock-based compensation | 13 | 17 | 15 | 11 | 3 | |
| Non-cash operating lease expense | 2 | 3 | 3 | 2 | 1 | |
| Other | 423,000 | 383,000 | 217,000 | 217,000 | 61,000 | |
| Prepaid expenses and other current assets | 547,000 | 857,000 | 101,000 | −3 | −3 | |
| Other noncurrent assets | 571,000 | 656,000 | −601,000 | −815,000 | −3 | |
| Accounts payable | −1 | −581,000 | −3 | 2 | 9 | |
| Accrued and other current liabilities | 532,000 | −5 | 2 | 4 | 3 | |
| Operating lease liabilities | −3 | −4 | −4 | −3 | −1 | |
| Other noncurrent liabilities | 102,000 | 0 | 1,000 | −1,000 | 163,000 | |
| Net cash used in operating activities | −68 | −91 | −102 | −104 | −61 | |
| Purchases of property and equipment | −618,000 | −1 | −1 | −21 | −25 | |
| Purchases of marketable securities | 0 | −87 | −57 | −140 | −213 | |
| Proceeds from sales of marketable securities | 11 | 8 | — | — | — | |
| Proceeds from maturities of marketable securities | 46 | 81 | 107 | 245 | — | |
| Other | 0 | 17,000 | −25,000 | 8,000 | — | |
| Net cash provided by investing activities | 56 | 1 | 49 | 84 | −239 | |
| Proceeds from exercise of stock options and employee stock purchase plan | 139,000 | 979,000 | 682,000 | 380,000 | 374,000 | |
| Proceeds from exercise of warrants | 2 | 0 | — | — | — | |
| Proceeds from exercises of pre-funded warrants | 0 | 8,000 | — | — | — | |
| Net cash provided by financing activities | 108 | 48 | 4 | 78 | 209 | |
| Net change in cash, cash equivalents and restricted cash | 96 | −42 | −49 | 57 | −90 | |
| Property and equipment included in accounts payable and accrued and other current liabilities | 60,000 | 358,000 | 249,000 | 549,000 | 4 | |
| Offering cost included in accounts payable and accrued expenses and other current liabilities | 415,000 | 0 | — | — | — | |
| Issuance of warrant in connection with Loan Agreement | 0 | 175,000 | — | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Tenaya Therapeutics, Inc.'s CIK number?
Tenaya Therapeutics, Inc.'s SEC CIK number is 0001858848 (1858848). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Tenaya Therapeutics, Inc.'s SEC filings?
All of Tenaya Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Tenaya Therapeutics, Inc. last report earnings?
Tenaya Therapeutics, Inc. (TNYA) most recently filed an earnings 8-K with the SEC on May 6, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-208975). This is Tenaya Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Tenaya Therapeutics, Inc.'s most recent earnings 8-K?
Tenaya Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 6, 2026 under accession 0001193125-26-208975. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Tenaya Therapeutics, Inc.'s latest earnings 8-K →
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