vTv Therapeutics Inc.
Business
vTv Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing orally administered therapies for metabolic and inflammatory diseases. Its main product candidate is cadisegliatin (TTP399), a liver-selective glucokinase activator being developed as an adjunct to insulin for type 1 diabetes, alongside other programs including an oral GLP-1 receptor agonist (TTP273), Nrf2/Bach1 modulators (HPP3033), and a PDE4 inhibitor (HPP737). The company conducts clinical development internally and through collaborations and licensing arrangements, with partnered programs and third-party manufacturing. vTv pursues regulatory and clinical activities in the United States and internationally, including trials in the Middle East and other partner territories.
Summary from filing dated 2025-03-20
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 0 | 1 | 0 | 2 | 4 | |
| Research and development | 18 | 12 | 14 | 12 | 13 | |
| General and administrative | 15 | 14 | 12 | 12 | 12 | |
| Total operating expenses | 33 | 25 | 26 | 25 | 26 | |
| Operating loss | −33 | −24 | −26 | −23 | −22 | |
| Interest income | 2 | 2 | 472,000 | 352,000 | 1,000 | |
| Interest expense | −6,000 | 0 | −13,000 | — | — | |
| Loss before income taxes and noncontrolling interest | −31 | −23 | −26 | −25 | −18 | |
| Income tax provision | 0 | 100,000 | 0 | 200,000 | 100,000 | |
| Net loss before noncontrolling interest | −31 | −23 | −26 | −25 | −18 | |
| Net loss attributable to noncontrolling interest | −4 | −4 | −6 | −6 | −5 | |
| Net loss attributable to vTv Therapeutics Inc. | −27 | −18 | −20 | −19 | −13 | |
| Net loss attributable to vTv Therapeutics Inc. common shareholders | −27 | −18 | −20 | −19 | −13 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 89 | 37 | 9 | 12 | 13 | |
| Prepaid expenses | 743,000 | 1 | — | — | — | |
| Other current assets | 218,000 | 175,000 | — | — | — | |
| Total current assets | 90 | 38 | 11 | 27 | 16 | |
| Other assets | 6,000 | 153,000 | — | — | — | |
| Total assets | 90 | 38 | 11 | 33 | 25 | |
| Accounts payable and accrued expenses | 7 | 5 | 10 | 7 | 8 | |
| Current portion of operating lease liabilities | 0 | 169,000 | 169,000 | 154,000 | 184,000 | |
| Total current liabilities | 7 | 5 | 11 | 8 | 8 | |
| Contract liabilities, net of current portion | 19 | 19 | 19 | 19 | 0 | |
| Total liabilities | 25 | 24 | 30 | 27 | 10 | |
| Commitments and contingencies | — | — | — | — | — | |
| Additional paid-in capital | 391 | 312 | 256 | 255 | 238 | |
| Accumulated deficit | −327 | −300 | −281 | −266 | −249 | |
| Total stockholders equity attributable to vTv Therapeutics Inc. | 64 | 12 | −25 | −11 | −10 | |
| Noncontrolling interest | 0 | 2 | 0 | — | — | |
| Total stockholders equity | 64 | 14 | −25 | −11 | −10 | |
| Total liabilities, redeemable noncontrolling interest and stockholders equity | 90 | 38 | 11 | 33 | 25 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation expense | 16,000 | 89,000 | 90,000 | 100,000 | 100,000 | |
| Loss on disposal of property and equipment | 6,000 | 0 | 0 | — | — | |
| Loss from G42 Promissory Note early redemption | 0 | 0 | 313,000 | 0 | 0 | |
| Non-cash interest income | 0 | 0 | −100,000 | −352,000 | 0 | |
| Share-based compensation expense | 4 | 3 | 2 | 1 | 2 | |
| Realized gain on sale of investment in Reneo Pharmaceuticals, Inc. | 0 | 0 | −3 | 0 | 0 | |
| Impairment of investments in Anteris Bio, Inc. | 0 | 0 | 4 | 0 | 0 | |
| Prepaid expenses | 449,000 | −216,000 | 2 | −403,000 | −839,000 | |
| Other current assets | −43,000 | 60,000 | −37,000 | — | — | |
| Other assets | 125,000 | 119,000 | 105,000 | — | — | |
| Accounts payable and accrued expenses | 2 | −5 | 3 | −856,000 | 2 | |
| Contract liabilities | 0 | −17,000 | 0 | 7 | −1 | |
| Other liabilities | −169,000 | −169,000 | −154,000 | 0 | −50,000 | |
| Net cash used in operating activities | −25 | −25 | −19 | −16 | −19 | |
| Proceed from sale of investments in Reneo Pharmaceuticals, Inc. | 0 | 0 | 4 | 0 | 0 | |
| Net cash provided by (used in) investing activities | 0 | 0 | 4 | −21,000 | 0 | |
| Proceeds from sale of Class A common stock, pre-funded and common warrants, net of offering costs | 77 | 0 | 0 | — | — | |
| Proceeds from sale of Class A common stock and pre-funded warrants, net of offering costs | 0 | 50 | 0 | 0 | 0 | |
| Proceeds from issuance of Class A common stock, net of offering costs | 0 | 2 | 0 | 0 | 27 | |
| Proceeds from sale of Class A common stock to collaboration partner, net of offering costs | 0 | 0 | 12 | 5 | 0 | |
| Proceeds from the exercise of stock options | 16,000 | 0 | 0 | 0 | 47,000 | |
| Taxes paid related to net share settlement of equity awards | −51,000 | 0 | 0 | — | — | |
| Proceeds from debt issuance | 392,000 | 0 | 566,000 | 776,000 | 887,000 | |
| Repayment of notes payable | −392,000 | −191,000 | −599,000 | −808,000 | −715,000 | |
| Net cash provided by financing activities | 77 | 53 | 12 | 15 | 27 | |
| Net increase (decrease) in cash, cash equivalents | 52 | 27 | −3 | −1 | 8 | |
| Cash paid for interest | 6,000 | 2,000 | 14,000 | 15,000 | 11,000 | |
| Cash paid for income taxes | 0 | 100,000 | 0 | 200,000 | 115,000 | |
| Reclassification of noncontrolling interest to additional paid-in capital | 2 | 5 | 0 | 0 | — |