Zai Lab Ltd
Business
Zai Lab Ltd is a patient-focused, commercial-stage global biopharmaceutical company that discovers, develops, and commercializes therapies addressing unmet needs in oncology, immunology, neuroscience, and infectious disease. It markets approved products such as ZEJULA, VYVGART (and VYVGART Hytrulo), NUZYRA, OPTUNE, QINLOCK, XACDURO, and AUGTYRO, and advances a pipeline of small molecules, biologics, ADCs, and medical devices. Its primary operations comprise commercial activities, integrated R&D (discovery through clinical development), manufacturing (in-house and CMOs), and licensing/collaboration. Zai Lab primarily serves Greater China (mainland China, Hong Kong, Macau, Taiwan) while engaging with U.S. and global partners and distributor channels.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Product revenue, net | 457 | 398 | 267 | 213 | 144 | |
| Collaboration revenue | 3 | 1 | 0 | 2 | 207,000 | |
| Total revenues | 460 | 399 | 267 | 215 | 144 | |
| Cost of product revenue | −191 | −147 | −96 | −74 | — | |
| Cost of collaboration revenue | −561,000 | −742,000 | 0 | 0 | — | |
| Research and development | −221 | −235 | −266 | −286 | −573 | |
| Selling, general, and administrative | −278 | −299 | −282 | −259 | −219 | |
| Gain on sale of intellectual property | 0 | 0 | 10 | 0 | 0 | |
| Loss from operations | −229 | −282 | −367 | −404 | −700 | |
| Interest income | 33 | 37 | 40 | 15 | 2 | |
| Interest expenses | −5 | −2 | 0 | — | — | |
| Foreign currency gains (losses) | 20 | −15 | −15 | −56 | 5 | |
| Other income, net | 4 | 5 | 7 | 3 | −10 | |
| Loss before income tax | −178 | −257 | −335 | — | — | |
| Income tax benefit | 3 | 0 | 0 | 0 | 0 | |
| Net loss | −176 | −257 | −335 | −443 | −704 | |
| Loss per share basic (in dollars per share) | −0.16 | −0.26 | −0.35 | −0.46 | −0.76 | |
| Loss per share diluted (in dollars per share) | −0.16 | −0.26 | −0.35 | −0.46 | −0.76 | |
| Weighted-average shares used in calculating net loss per ordinary share basic (in shares) | 1,095 | 989 | 966 | 958 | 930 | |
| Weighted-average shares used in calculating net loss per ordinary share diluted (in shares) | 1,095 | 989 | 966 | 958 | 930 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 680 | 450 | 790 | 1,008 | 964 | |
| Restricted cash, current | 100 | 100 | 0 | — | — | |
| Short-term investments | 10 | 330 | 16 | 0 | 445 | |
| Accounts receivable (net of allowance for credit losses of $31 and $25 as of December 31, 2025 and 2024, respectively) | 106 | 85 | 59 | 40 | 47 | |
| Notes receivable | 12 | 4 | 6 | 9 | 7 | |
| Inventories, net | 75 | 40 | 45 | 32 | 19 | |
| Prepayments and other current assets | 37 | 42 | 23 | 36 | 18 | |
| Total current assets | 1,019 | 1,050 | 940 | 1,124 | 1,501 | |
| Restricted cash, non-current | 1 | 1 | 1 | 800,000 | 803,000 | |
| Property and equipment, net | 47 | 48 | 54 | 58 | 43 | |
| Operating lease right-of-use assets | 19 | 21 | 15 | 20 | 14 | |
| Land use rights, net | 3 | 3 | 3 | 7 | 8 | |
| Intangible assets, net | 76 | 56 | 13 | 2 | 2 | |
| Deferred tax assets | 3 | 0 | — | — | — | |
| Other non-current assets | 3 | 6 | — | — | — | |
| Total assets | 1,172 | 1,186 | 1,036 | 1,220 | 1,610 | |
| Accounts payable | 142 | 101 | 113 | 66 | 126 | |
| Current operating lease liabilities | 6 | 8 | 7 | 7 | 6 | |
| Short-term debt | 205 | 132 | 0 | — | — | |
| Other current liabilities | 64 | 59 | 83 | 67 | 61 | |
| Total current liabilities | 416 | 299 | 203 | 140 | 193 | |
| Deferred income | 27 | 31 | 29 | 21 | 27 | |
| Non-current operating lease liabilities | 13 | 14 | 8 | 13 | 10 | |
| Other non-current liabilities | 0 | 325,000 | 325,000 | 0 | — | |
| Total liabilities | 457 | 345 | 240 | 175 | 230 | |
| Commitments and contingencies (Note 20) | — | — | — | — | — | |
| Ordinary shares (par value of $0.000006 per share; 5,000,000,000 shares authorized; 1,113,822,550 and 1,082,614,740 shares issued as of December 31, 2025 and 2024, respectively; 1,106,389,340 and 1,077,702,540 shares outstanding as of December 31, 2025 and 2024, respectively) | 7,000 | 7,000 | 6,000 | 6,000 | 6,000 | |
| Additional paid-in capital | 3,343 | 3,264 | 2,975 | 2,893 | 2,826 | |
| Accumulated deficit | −2,629 | −2,453 | −2,196 | −1,861 | −1,418 | |
| Accumulated other comprehensive income | 30 | 51 | 38 | 26 | −24 | |
| Treasury stock (at cost 7,433,210 and 4,912,200 shares as of December 31, 2025 and 2024, respectively) | −29 | −21 | −21 | −12 | −4 | |
| Total shareholders equity | 716 | 841 | 796 | 1,046 | 1,380 | |
| Total liabilities and shareholders equity | 1,172 | 1,186 | 1,036 | 1,220 | 1,610 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Allowance for credit losses | 6,000 | 8,000 | 6,000 | 1,000 | 10,000 | |
| Inventory write-down | 12 | 815,000 | 973,000 | 477,000 | 1 | |
| Depreciation and amortization expenses | 15 | 12 | 9 | 8 | 6 | |
| Impairment of property and equipment | 0 | 0 | 57,000 | 0 | 0 | |
| Amortization of deferred income | −5 | −4 | −3 | −3 | −521,000 | |
| Share-based compensation | 66 | 71 | 80 | 61 | 41 | |
| Loss (gain) from fair value changes of equity investment with readily determinable fair value | 2 | 6 | −3 | 9 | 15 | |
| Losses on disposal of property and equipment | 542,000 | 453,000 | 159,000 | 560,000 | 29,000 | |
| Gain on disposal of land use right | 0 | 0 | −408,000 | 0 | 0 | |
| Noncash lease expenses | 9 | 8 | 9 | 8 | 6 | |
| Foreign currency remeasurement impact | −20 | 15 | 15 | 56 | −11 | |
| Amortization of debt issuance cost | 194,000 | 700,000 | 0 | 0 | — | |
| Accounts receivable | −19 | −27 | −20 | 4 | −42 | |
| Notes receivable | −8 | 2 | 2 | −2 | −7 | |
| Inventories | −47 | 4 | −15 | −15 | −7 | |
| Prepayments and other current assets | 5 | −19 | 12 | −19 | −7 | |
| Deferred tax assets | −3 | 0 | 0 | — | — | |
| Other non-current assets | −374,000 | −1 | 187,000 | — | — | |
| Accounts payable | 20 | −2 | 37 | −54 | 64 | |
| Other current liabilities | 5 | −22 | 20 | 7 | 30 | |
| Operating lease liabilities | −7 | −9 | −8 | −8 | −5 | |
| Deferred income | 745,000 | 7 | 11 | −1 | 11 | |
| Other non-current liabilities | −325,000 | 0 | 325,000 | 0 | 0 | |
| Net cash used in operating activities | −151 | −215 | −198 | −368 | −549 | |
| Purchases of short-term investments | −10 | −330 | −134 | −260 | −445 | |
| Proceeds from maturity of short-term investment | 330 | 16 | 118 | 705 | 744 | |
| Proceeds from the sale of equity investment | 1 | 0 | 0 | — | — | |
| Purchases of property and equipment | −8 | −6 | −7 | −25 | −18 | |
| Proceeds from the sale of property and equipment | 87,000 | 29,000 | 122,000 | 0 | 3,000 | |
| Acquisition of intangible assets | −5 | −56 | −1 | −399,000 | −653,000 | |
| Proceeds from sale of intellectual property | 0 | 0 | 10 | 0 | 0 | |
| Proceeds from disposal of land use right | 0 | 0 | 4 | 0 | 0 | |
| Net cash provided by (used in) investing activities | 308 | −375 | −11 | 420 | 250 | |
| Proceeds from short-term debt | 207 | 132 | 0 | 0 | — | |
| Repayment of short-term bank borrowings | −139 | −284,000 | 0 | 0 | 0 | |
| Payments of debt issuance costs | −194,000 | −700,000 | 0 | 0 | — | |
| Proceeds from exercises of stock options | 14 | 3 | 2 | 6 | 7 | |
| Proceeds from issuance of ordinary shares upon public offerings | 0 | 217 | 0 | 0 | — | |
| Payments of public offering costs | −854,000 | −1 | 0 | 0 | −2 | |
| Taxes paid related to settlement of equity awards | −8 | 0 | −9 | −8 | −4 | |
| Net cash provided by (used in) financing activities | 72 | 350 | −6 | −2 | 820 | |
| Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash | 478,000 | −310,000 | −3 | −6 | 1 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 230 | −240 | −218 | 44 | 522 | |
| Cash paid for interest | 5 | 2 | 0 | 0 | 0 | |
| Payables for purchase of property and equipment | 486,000 | 449,000 | 2 | 5 | 3 | |
| Payables for acquisition of intangible assets | 22 | 3 | 12 | 163,000 | 191,000 | |
| Payables for public offering costs | 168,000 | 994,000 | 0 | 0 | 0 | |
| Right-of-use asset acquired under operating leases | 6 | 15 | 4 | 15 | 2 | |
| Receivables for stock option exercise under equity incentive plans | 0 | 70,000 | 0 | 0 | — |