NEUROCRINE BIOSCIENCES INC
Business
NEUROCRINE BIOSCIENCES INC is a neuroscience-focused biopharmaceutical company that discovers, develops and commercializes therapies for neuropsychiatric, neurological and neuroendocrine disorders. It offers FDA-approved VMAT2 inhibitors for tardive dyskinesia and chorea, a CRF1 receptor antagonist for congenital adrenal hyperplasia, licensed elagolix therapies for gynecologic conditions, and a diversified pipeline spanning small molecules, peptides, proteins, antibodies and gene therapies. Key operations include commercial sales, clinical development, outsourced manufacturing oversight, patent management and strategic collaborations. Products are marketed primarily in the U.S., with partner-led launches and royalty arrangements in Japan, select Asian and other international markets, using specialty pharmacies, distributors and dedicated specialty sales teams.
Summary from filing dated 2025-02-10
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 2,861 | 2,355 | 1,887 | 1,489 | 1,134 | |
| Cost of revenues | 52 | 34 | 40 | 23 | 14 | |
| Research and development | 1,016 | 731 | 565 | 464 | 328 | |
| Acquired in-process research and development | 17 | 13 | 144 | 0 | 105 | |
| Selling, general, and administrative | 1,156 | 1,007 | 888 | 753 | 583 | |
| Total operating expenses | 2,241 | 1,785 | 1,636 | 1,240 | 1,031 | |
| Operating income | 619 | 571 | 251 | 249 | 103 | |
| Unrealized (loss) gain on equity investments | −4 | −37 | 28 | 31 | 21 | |
| Charges associated with convertible senior notes | 0 | −138 | 0 | −70 | — | |
| Investment income and other, net | 90 | 91 | 53 | 4 | 4 | |
| Total other income (expense), net | 86 | −85 | 81 | −35 | −1 | |
| Income before provision for income taxes | 705 | 486 | 332 | 214 | 101 | |
| Provision for income taxes | 227 | 145 | 82 | 59 | 12 | |
| Net income | 479 | 341 | 250 | 155 | 90 | |
| Foreign currency translation adjustments, net of tax | 4 | −1 | 2 | 3 | 0 | |
| Unrealized gain (loss) on available-for-sale debt securities, net of tax | 4 | −100,000 | 13 | −9 | −4 | |
| Comprehensive income | 486 | 340 | 265 | 148 | 86 | |
| Earnings per share, basic (in USD per share) | 4.81 | 3.4 | 2.56 | 1.61 | 0.95 | |
| Earnings per share, diluted (in USD per share) | 4.67 | 3.29 | 2.47 | 1.56 | 0.92 | |
| Weighted average common shares outstanding, basic (in shares) | 100 | 100 | 98 | 96 | 95 | |
| Weighted average common shares outstanding, diluted (in shares) | 103 | 104 | 101 | 99 | 98 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 713 | 233 | 251 | 263 | 341 | |
| Available-for-sale debt securities | 767 | 843 | 781 | 726 | 371 | |
| Accounts receivable | 687 | 479 | 439 | 350 | 186 | |
| Inventory | 69 | 57 | 38 | 35 | 31 | |
| Prepaid expenses | 171 | 49 | — | — | — | |
| Other current assets | 116 | 64 | 98 | 79 | 46 | |
| Total current assets | 2,523 | 1,725 | 1,607 | 1,454 | 973 | |
| Deferred tax assets | 320 | 486 | 363 | 306 | 315 | |
| Available-for-sale debt securities | 1,063 | 740 | 688 | 299 | — | |
| Right-of-use assets | 455 | 509 | 277 | 87 | 97 | |
| Equity investments | 121 | 125 | 162 | 102 | — | |
| Property and equipment, net | 90 | 83 | 71 | 59 | 59 | |
| Other noncurrent assets | 60 | 52 | 50 | 25 | 4 | |
| Total assets | 4,632 | 3,719 | 3,251 | 2,369 | 2,073 | |
| Accounts payable and accrued liabilities | 674 | 462 | 449 | 348 | 226 | |
| Other current liabilities | 69 | 46 | 36 | 21 | 20 | |
| Total current liabilities | 743 | 508 | 655 | 538 | 246 | |
| Noncurrent operating lease liabilities | 415 | 455 | 258 | 94 | 105 | |
| Other noncurrent liabilities | 220 | 166 | 106 | 30 | 12 | |
| Total liabilities | 1,378 | 1,129 | 1,019 | 661 | 699 | |
| Preferred stock, $0.001 par value; 5.0 shares authorized; no shares issued and outstanding | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value; 220.0 shares authorized; 100.1 and 99.4 shares issued and outstanding, respectively | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | |
| Additional paid-in capital | 2,792 | 2,555 | 2,382 | 2,122 | 2,011 | |
| Accumulated other comprehensive income | 13 | 6 | 7 | −8 | −2 | |
| Retained earnings | 448 | 29 | −157 | −407 | −636 | |
| Total stockholders equity | 3,253 | 2,590 | 2,232 | 1,708 | 1,374 | |
| Total liabilities and stockholders equity | 4,632 | 3,719 | 3,251 | 2,369 | 2,073 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation | 218 | 196 | 194 | 173 | 134 | |
| Impairment charges associated with leased properties | 700,000 | 14 | 0 | — | — | |
| Depreciation | 26 | 24 | 18 | 15 | 11 | |
| Accretion of discount on available-for-sale debt securities, net | −13 | −26 | −18 | 4 | 7 | |
| Amortization of acquired intangible assets | 4 | 4 | 4 | 500,000 | 0 | |
| Deferred tax assets | 165 | −123 | −57 | 19 | 4 | |
| Non-cash lease expense | 27 | 10 | −900,000 | — | — | |
| Other | 700,000 | 100,000 | 700,000 | 2 | −3 | |
| Accounts receivable | −211 | −40 | −89 | −162 | −28 | |
| Inventory | −15 | −19 | 5 | −3 | −3 | |
| Accounts payable and accrued liabilities | 160 | 43 | 49 | 115 | 57 | |
| Income tax assets and liabilities | −19 | 50 | 92 | — | — | |
| Other assets and liabilities, net | −44 | −54 | −29 | −17 | −9 | |
| Cash flows from operating activities | 783 | 595 | 390 | 339 | 257 | |
| Purchases of available-for-sale debt securities | −1,320 | −1,056 | −1,380 | −621 | −800 | |
| Sales and maturities of available-for-sale debt securities | 1,089 | 968 | 972 | 511 | 698 | |
| Purchases of equity investments | 0 | 0 | −31 | −8 | −5 | |
| Capital expenditures | −34 | −38 | −28 | −17 | −23 | |
| Cash flows from investing activities | −264 | −127 | −467 | −177 | −130 | |
| Issuances of common stock under benefit plans | 129 | 122 | 65 | 45 | 28 | |
| Repurchases of common stock | −168 | −300 | 0 | 0 | — | |
| Payments to settle convertible senior notes | 0 | −309 | 0 | −279 | −100,000 | |
| Cash flows from financing activities | −38 | −487 | 65 | −234 | 27 | |
| Effect of exchange rate changes on cash and cash equivalents | 0 | 0 | 300,000 | −1 | 0 | |
| Change in cash and cash equivalents and restricted cash | 480 | −18 | −12 | −73 | 154 | |
| Accrued capital expenditures | 2 | 2 | 3 | 700,000 | 2 | |
| Right-of-use assets acquired through operating leases | 0 | 272 | 201 | 0 | 23 | |
| Cash paid for interest | 0 | 2 | 4 | 7 | 9 | |
| Cash paid for income taxes | 81 | 218 | 52 | 14 | 5 |