CYTOKINETICS INC
Business
Cytokinetics is a biopharmaceutical company discovering and developing small-molecule muscle activators and inhibitors for cardiovascular and neuromuscular diseases. Its first approved product, MYQORZO (aficamten), a cardiac myosin inhibitor, treats symptomatic obstructive hypertrophic cardiomyopathy. The company is advancing omecamtiv mecarbil for heart failure with reduced ejection fraction, ulacamten for heart failure with preserved ejection fraction, and CK-089 for muscular dystrophy. Commercial distribution occurs through specialty sales forces; international expansion is supported by licensing partnerships with Sanofi and Bayer.
Summary from 10-K filed 2026-02-26
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 88 | 18 | 8 | 95 | 70 | |
| Research and development | 416 | 339 | 330 | 241 | 160 | |
| General and administrative | 284 | 215 | 174 | 178 | 97 | |
| Total operating expenses | 700 | 555 | 504 | 419 | 257 | |
| Operating loss | −612 | −536 | −496 | −324 | −186 | |
| Interest expense | −46 | −38 | −28 | −19 | −16 | |
| Non-cash interest expense on liabilities related to revenue participation right purchase agreements | −58 | −49 | −29 | −32 | −13 | |
| Interest and other income, net | 48 | 52 | 28 | 11 | 331,000 | |
| Change in fair value of derivative liabilities | 4 | 1 | 0 | 0 | — | |
| Change in fair value of liabilities related to RPI Transactions | −200,000 | −20 | 0 | 0 | — | |
| Debt conversion expense | −121 | 0 | 0 | — | — | |
| Net loss | −785 | −590 | −526 | −389 | −215 | |
| Net loss per share - basic | −6.54 | −5.26 | −5.45 | −4.33 | −2.8 | |
| Net loss per share - diluted | −6.54 | −5.26 | −5.45 | −4.33 | −2.8 | |
| Weighted-average number of shares used in computing net loss per share - basic | 120,103 | 111,979 | 96,524 | 89,825 | 76,886 | |
| Weighted-average number of shares used in computing net loss per share - diluted | 120,103 | 111,979 | 96,524 | 89,825 | 76,886 | |
| Unrealized (loss) gain on available-for-sale securities, net | −990,000 | 2 | 4 | −3 | −1 | |
| Foreign currency translation adjustments | −778,000 | 255,000 | −20,000 | 0 | 0 | |
| Comprehensive loss | −787 | −587 | −523 | −392 | −216 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 123 | 95 | 113 | 66 | 113 | |
| Short-term investments | 760 | 981 | 502 | 717 | 359 | |
| Accounts receivable | 18 | 17 | 1 | 147,000 | 52 | |
| Prepaid expenses and other current assets | 17 | 15 | 12 | 12 | 12 | |
| Total current assets | 917 | 1,108 | 628 | 795 | 536 | |
| Long-term investments | 335 | 145 | 41 | 47 | 152 | |
| Property and equipment, net | 79 | 66 | 69 | 80 | 73 | |
| Operating lease right-of-use assets | 76 | 75 | 79 | 83 | 73 | |
| Other assets | 17 | 8 | 8 | 10 | 7 | |
| Total assets | 1,425 | 1,402 | 824 | 1,015 | 841 | |
| Accounts payable | 22 | 20 | 22 | 26 | 21 | |
| Accrued liabilities | 83 | 55 | 43 | 44 | 34 | |
| Short-term operating lease liabilities | 19 | 19 | 18 | 13 | 15 | |
| Current portion of convertible and long-term debt | 41 | 12 | 10 | 958,000 | — | |
| Derivative liabilities measured at fair value | 31 | 11 | 0 | — | — | |
| Deferred revenue | 2 | 52 | 0 | — | — | |
| Other current liabilities | 4 | 10 | 11 | 1 | 2 | |
| Total current liabilities | 202 | 180 | 103 | 85 | 72 | |
| Term loans, net | 246 | 93 | 58 | 64 | 47 | |
| Convertible notes, net | 870 | 552 | — | — | — | |
| Liabilities related to revenue participation right purchase agreements, net | 521 | 462 | 380 | 301 | 179 | |
| Long-term operating lease liabilities | 108 | 113 | 120 | 127 | 112 | |
| Liabilities related to RPI Transactions measured at fair value | 137 | 137 | 0 | — | — | |
| Total liabilities | 2,084 | 1,537 | 1,211 | 1,123 | 597 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, $0.001 par value: Authorized: 10,000,000 shares; Issued and outstanding: none | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value: Authorized: 163,000,000 shares Issued and outstanding: 122,943,172 shares at December 31, 2025 and 118,209,139 shares at December 31, 2024 | 123,000 | 118,000 | 102,000 | 94,000 | 84,000 | |
| Additional paid-in capital | 2,826 | 2,564 | 1,726 | 1,482 | 1,452 | |
| Accumulated other comprehensive income | 630,000 | 2 | −10,000 | −4 | −869,000 | |
| Accumulated deficit | −3,500 | −2,702 | −2,112 | −1,586 | −1,197 | |
| Total stockholders' deficit | −660 | −135 | −386 | −108 | 244 | |
| Total liabilities and stockholders' deficit | 1,425 | 1,402 | 824 | 1,015 | 841 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −785 | −590 | −526 | −389 | −215 | |
| Non-cash interest expense on liabilities related to revenue participation right purchase agreement | 58 | 49 | 29 | 32 | 13 | |
| Stock-based compensation expense | 112 | 98 | 72 | 48 | 27 | |
| Non-cash lease expense | 6 | 4 | 4 | 3 | 7 | |
| Loss on disposition of property and equipment | 0 | 45,000 | 0 | 0 | — | |
| Depreciation of property and equipment | 10 | 10 | 12 | 6 | 2 | |
| Realized (loss) gain on investment, net | −25,000 | −19,000 | 35,000 | 107,000 | — | |
| Interest receivable and amortization on investments | −16 | −33 | −16 | −5 | 5 | |
| Non-cash interest expense related to debt | 23 | 12 | 7 | 6 | 7 | |
| Accounts receivable | −1 | −15 | −1 | 57 | −47 | |
| Prepaid and other assets | −3 | −2 | 2 | −7 | −7 | |
| Accounts payable | 3 | −4 | −3 | 5 | 1 | |
| Deferred revenue | −51 | 52 | 0 | −87 | 0 | |
| Accrued and other liabilities | 34 | 14 | 17 | 11 | 15 | |
| Operating lease liabilities | −11 | −7 | −1 | 2 | 43 | |
| Other non-current liabilities | −6 | −1 | −10 | −4 | 4 | |
| Net cash used in operating activities | −510 | −396 | −414 | −300 | −143 | |
| Purchases of investments | −1,063 | −1,293 | −635 | −855 | −525 | |
| Investment in non-marketable equity security | −5 | 0 | 0 | — | — | |
| Maturities of investments | 1,104 | 744 | 871 | 605 | 423 | |
| Sales of investments | 6 | 0 | 5 | 0 | 3 | |
| Purchases of property and equipment | −25 | −4 | −1 | −11 | −49 | |
| Net cash (used in) provided by investing activities | 17 | −553 | 239 | −262 | −148 | |
| Repayment of finance lease liabilities | −204,000 | −939,000 | −858,000 | −944,000 | 0 | |
| Repayment of term loan | −11 | −9 | 0 | −48 | 0 | |
| Repayment of convertible debt | −403 | 0 | 0 | −140 | 0 | |
| Proceeds from issuance of convertible debt, net | 729 | 0 | 0 | 524 | 0 | |
| Proceeds from draw on RPI Multi Tranche Loan | 175 | 200 | 50 | — | — | |
| Proceeds from issuance of common stock related to private placement, net of issuance costs | 0 | 50 | 0 | 0 | 15 | |
| Proceeds from issuance of common stock under equity incentive and stock purchase plans | 36 | 53 | 18 | 18 | 12 | |
| Taxes paid related to net share settlement of equity awards | −2 | −20 | −11 | −10 | −4 | |
| Net cash provided by financing activities | 524 | 931 | 221 | 516 | 320 | |
| Effect of exchange rate changes | −715,000 | 209,000 | −20,000 | — | — | |
| Net (decrease) increase in cash, cash equivalents, and restricted cash | 30 | −18 | 46 | −45 | 30 | |
| Cash paid for interest | 23 | 26 | 10 | 15 | 9 | |
| Right-of-use assets recognized in exchange for operating lease obligations | 6 | 481,000 | 0 | 11 | 80 | |
| Amounts unpaid for purchases of property and equipment | 3 | 3 | 0 | 621,000 | 12 | |
| Issuance of common stock in connection with repurchase of convertible note | 108 | 0 | 0 | 317 | 0 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is CYTOKINETICS INC's CIK number?
CYTOKINETICS INC's SEC CIK number is 0001061983 (1061983). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find CYTOKINETICS INC's SEC filings?
All of CYTOKINETICS INC's EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did CYTOKINETICS INC last report earnings?
CYTOKINETICS INC (CYTK) most recently filed an earnings 8-K with the SEC on May 5, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-206360). This is CYTOKINETICS INC's most recent earnings filing of record — not a forecast of its next earnings date.
What is CYTOKINETICS INC's most recent earnings 8-K?
CYTOKINETICS INC's latest earnings 8-K (Item 2.02) was filed May 5, 2026 under accession 0001193125-26-206360. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View CYTOKINETICS INC's latest earnings 8-K →
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