PTC THERAPEUTICS, INC.
Business
PTC Therapeutics is a global biopharmaceutical company developing and commercializing clinically differentiated medicines for rare disorders affecting children and adults. The company offers commercial products including Sephience for phenylketonuria, Translarna and Emflaza for Duchenne muscular dystrophy, Upstaza/Kebilidi for aromatic L-amino acid decarboxylase deficiency, Evrysdi for spinal muscular atrophy, and Tegsedi and Waylivra for rare metabolic and neurological diseases. PTC operates through multiple geographic markets, including the United States, Europe, and Latin America, with a pipeline spanning splicing-modulation and inflammation/ferroptosis platforms targeting unmet neurological and metabolic needs.
Summary from 10-K filed 2026-02-19
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 1,731 | 807 | 938 | 699 | 539 | |
| Cost of product, collaboration and license sales, excluding amortization of acquired intangible assets | 47 | 57 | 65 | — | — | |
| Amortization of acquired intangible assets | 25 | 61 | 223 | 117 | 55 | |
| Research and development | 455 | 534 | 667 | 651 | 541 | |
| Selling, general and administrative | 347 | 301 | 333 | 326 | 286 | |
| Change in the fair value of contingent consideration | −800,000 | −4 | −128 | −26 | −500,000 | |
| Intangible asset impairment | — | 160 | 218 | 33 | — | |
| Tangible asset impairment and (gains) losses on transactions, net | −10 | 750,000 | — | — | — | |
| Total operating expenses | 864 | 1,109 | 1,377 | 1,146 | 913 | |
| Income (loss) from operations | 867 | −303 | −440 | −447 | −374 | |
| Interest expense, net | −152 | −167 | −129 | −91 | −86 | |
| Other (expense) income, net | −18 | 7 | 10 | −49 | −58 | |
| Gain on sale of priority review voucher | — | 100 | — | — | — | |
| Loss on extinguishment of debt | — | — | −138 | — | — | |
| Income (loss) before income tax (expense) benefit | 697 | −363 | −696 | −587 | −518 | |
| Income tax (expense) benefit | −14 | −176,000 | 70 | 28 | −6 | |
| Net income (loss) attributable to common stockholders | 683 | −363 | −627 | −559 | −524 | |
| Basic (in shares) | 80 | 77 | 75 | 72 | 70 | |
| Diluted (in shares) | 88 | 77 | 75 | 72 | 70 | |
| Basic | 8.58 | −4.73 | −8.37 | −7.79 | −7.43 | |
| Diluted | 7.78 | −4.73 | −8.37 | −7.79 | −7.43 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2025 2025-03-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 985 | — | 780 | 594 | 280 | |
| Marketable securities | 961 | — | 360 | 283 | 131 | |
| Trade and royalty receivables, net | 182 | — | 159 | 161 | 156 | |
| Inventory, net | 80 | — | 23 | 31 | 22 | |
| Prepaid expenses and other current assets | 67 | — | 44 | 150 | 106 | |
| Total current assets | 2,274 | — | 1,366 | 1,219 | 694 | |
| Fixed assets, net | 55 | — | 61 | 87 | 73 | |
| Intangible assets, net | 389 | — | 119 | 379 | 706 | |
| Goodwill | 82 | — | 82 | 82 | 82 | |
| Operating lease ROU assets | 80 | — | 57 | 92 | 102 | |
| Deposits and other assets | 18 | — | 21 | 36 | 49 | |
| Total assets | 2,899 | — | 1,705 | 1,896 | 1,706 | |
| Accounts payable and accrued expenses | 381 | — | 304 | 392 | 320 | |
| Current portion of long-term debt | 287 | — | — | — | — | |
| Deferred revenue | 2 | — | 6 | 801,000 | 1 | |
| Operating lease liabilities- current | 12 | — | 10 | 13 | 9 | |
| Finance lease liabilities- current | 3 | — | 3 | 3 | 3 | |
| Liability for sale of future royalties- current | 283 | — | 258 | 194 | 72 | |
| Total current liabilities | 968 | — | 581 | 603 | 406 | |
| Long-term debt | — | — | 285 | 284 | 572 | |
| Contingent consideration payable | — | 0 | 800,000 | 36 | 164 | |
| Operating lease liabilities- noncurrent | 94 | — | 75 | 98 | 101 | |
| Finance lease liabilities- noncurrent | 3 | — | 16 | 17 | 19 | |
| Liability for sale of future royalties- noncurrent | 2,025 | — | 1,824 | 1,620 | 686 | |
| Other long-term liabilities | 14 | — | 21 | 141,000 | 3 | |
| Total liabilities | 3,104 | — | 2,803 | 2,714 | 2,053 | |
| Common stock, $0.001 par value. Authorized 250,000,000 shares; issued and outstanding 81,474,366 shares at December 31, 2025. Authorized 250,000,000 shares; issued and outstanding 77,704,188 shares at December 31, 2024. | 80,000 | — | 77,000 | 75,000 | 72,000 | |
| Additional paid-in capital | 2,748 | — | 2,575 | 2,466 | 2,305 | |
| Accumulated other comprehensive income (loss) | 11 | — | −26 | −1 | 5 | |
| Accumulated deficit | −2,964 | — | −3,647 | −3,284 | −2,657 | |
| Total stockholders' deficit | −205 | — | −1,098 | −819 | −347 | |
| Total liabilities and stockholders' deficit | 2,899 | — | 1,705 | 1,896 | 1,706 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 39 | 76 | 237 | 129 | 64 | |
| Non-cash operating lease expense | 7 | 8 | 10 | 10 | 7 | |
| Non-cash royalty revenue related to sale of future royalties | −229 | −182 | −93 | −49 | −23 | |
| Non-cash interest expense on liability related to sale of future royalties | 215 | 207 | 105 | 73 | 78 | |
| Change in valuation of contingent consideration | −800,000 | −4 | −128 | −26 | −500,000 | |
| Tangible asset impairment | 1 | 4 | — | — | — | |
| Loss on sale of fixed assets | 100,000 | 4 | — | — | — | |
| Gain on lease terminations | — | −2 | — | — | — | |
| Gain on lease modification | −11 | −5 | — | — | — | |
| Unrealized (gain) loss on ClearPoint Equity Investments | −6 | −8 | 2 | 4 | 6 | |
| Unrealized loss on ClearPoint convertible debt security | — | 2 | 3 | 6 | 8 | |
| Realized loss on sale of ClearPoint Equity Investment | 7 | — | 782,000 | — | — | |
| Realized loss on ClearPoint convertible debt security | — | 622,000 | — | — | — | |
| Realized gain on sale of marketable securities - equity investments | — | — | −4 | — | — | |
| Unrealized gain on marketable securities - equity investments | −4 | −3 | −3 | 8 | −2 | |
| Non-cash stock consideration, milestone payment | — | — | 30 | — | — | |
| Disposal of asset | 163,000 | 345,000 | 806,000 | 80,000 | — | |
| Deferred income taxes | −3,000 | −56 | −47 | −34 | 377,000 | |
| Amortization of discounts on investments, net | −18 | −13 | −2 | 2 | 5 | |
| Amortization of debt issuance costs | 1 | 1 | 2 | 2 | 2 | |
| Loss on extinguishment of debt | — | — | 56 | — | — | |
| Share-based compensation expense | 75 | 75 | 102 | 110 | 104 | |
| Unrealized foreign currency transaction losses (gains), net | 3 | −10 | −14 | 13 | 47 | |
| Inventory, net | −54 | 6 | −8 | −7 | 2 | |
| Prepaid expenses and other current assets | −37 | 99 | −45 | −52 | −15 | |
| Trade and royalty receivables, net | −10 | 2 | −2 | −48 | −45 | |
| Deposits and other assets | 3 | 12 | 5 | −3 | −232,000 | |
| Accounts payable and accrued expenses | 72 | −33 | 48 | 28 | 46 | |
| Other liabilities | −17 | 12 | −2 | −5 | −7 | |
| Deferred revenue | −4 | 5 | −550,000 | 1 | −4 | |
| Payments on contingent consideration | −5 | −2 | — | −10 | — | |
| Net cash provided by (used in) operating activities | 711 | −108 | −158 | −357 | −251 | |
| Purchases of fixed assets | −9 | −7 | −28 | −32 | −28 | |
| Proceeds from sale of fixed assets | 70,000 | 28 | — | — | — | |
| Proceeds from sale of priority review voucher | — | 150 | — | — | — | |
| Purchases of marketable securities- available for sale | −1,364 | −608 | −174 | −53 | −333 | |
| Purchases of marketable securities- equity investments | −54 | −59 | −38 | −23 | −210 | |
| Sale of marketable securities- available for sale | 784 | 550 | 22 | 405 | 843 | |
| Sale of marketable securities- equity investments | 59 | 48 | 132 | 113 | 4 | |
| Sale of ClearPoint Equity Investments | 12 | — | 3 | — | — | |
| Proceeds from settlement of Clearpoint convertible debt security | — | 10 | — | — | — | |
| Acquisition of product rights and licenses | −291 | −68 | −92 | −120 | −57 | |
| Net cash (used in) provided by investing activities | −862 | 44 | −177 | 290 | 219 | |
| Proceeds from exercise of options | 93 | 29 | 24 | 15 | 17 | |
| Proceeds from employee stock purchase plan | 6 | 5 | 6 | 6 | 6 | |
| Repayment of senior secured term loan | — | — | −300 | — | — | |
| Debt extinguishment costs related to senior secured term loan | — | — | −82 | — | — | |
| Cash consideration received from A&R Royalty Purchase Agreement | 240 | 242 | 1,000 | — | — | |
| Debt issuance costs related to senior secured term loan | — | — | −282,000 | −11 | — | |
| Payments on contingent consideration obligation | −6 | −18 | — | −40 | — | |
| Payment of finance lease principal | −2 | −1 | −1 | −1 | −2 | |
| Net cash provided by financing activities | 331 | 256 | 646 | 168 | 21 | |
| Effect of exchange rate changes on cash | 23 | −7 | 3 | −3 | −8 | |
| Net increase in cash and cash equivalents | 203 | 185 | 314 | 99 | −19 | |
| Cash paid for interest | 6 | 6 | 36 | 18 | 10 | |
| Federal | 27 | — | — | — | — | |
| Total income taxes paid, net of refunds recieved | 37 | 18 | 14 | 5 | 8 | |
| Right-of-use assets obtained in exchange for operating lease obligations | 28 | 6 | — | 36 | 645,000 | |
| Acquisition of product rights and licenses | 1 | 420,000 | 55 | 33 | 22 | |
| Fixed asset additions through tenant improvement allowance | 766,000 | 19 | — | — | — | |
| Capital expenditures unpaid at the end of period | 126,000 | 70,000 | — | 308,000 | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is PTC THERAPEUTICS, INC.'s CIK number?
PTC THERAPEUTICS, INC.'s SEC CIK number is 0001070081 (1070081). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find PTC THERAPEUTICS, INC.'s SEC filings?
All of PTC THERAPEUTICS, INC.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did PTC THERAPEUTICS, INC. last report earnings?
PTC THERAPEUTICS, INC. (PTCT) most recently filed an earnings 8-K with the SEC on May 7, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001070081-26-000011). This is PTC THERAPEUTICS, INC.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is PTC THERAPEUTICS, INC.'s most recent earnings 8-K?
PTC THERAPEUTICS, INC.'s latest earnings 8-K (Item 2.02) was filed May 7, 2026 under accession 0001070081-26-000011. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View PTC THERAPEUTICS, INC.'s latest earnings 8-K →
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