ACADIA PHARMACEUTICALS INC
Business
ACADIA PHARMACEUTICALS INC is a biopharmaceutical company focused on developing and commercializing medicines for central nervous system (CNS) disorders and rare neurodevelopmental diseases. It commercializes NUPLAZID (pimavanserin) for Parkinson’s disease psychosis and DAYBUE (trofinetide) for Rett syndrome and advances a pipeline including ACP-101, ACP-204 and ACP-711. The company operates through two core franchises—neuroscience and neuro-rare diseases—supported by R&D, regulatory and commercial functions. It markets and distributes products primarily in the United States and Canada and pursues approvals and launches in the European Union, Japan and other global markets via specialty pharmacies, distributors and direct-to-patient channels.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 1,072 | 958 | 726 | 517 | 484 | |
| Cost of product sales | 89 | 82 | 42 | 10 | 19 | |
| Research and development | 329 | 303 | 352 | 362 | 239 | |
| Selling, general and administrative | 549 | 488 | 407 | 369 | 396 | |
| Gain on sale of non-financial asset | 0 | −147 | 0 | 0 | — | |
| Total operating expenses | 967 | 727 | 800 | 741 | 655 | |
| Income (loss) from operations | 105 | 231 | −73 | −224 | −170 | |
| Interest income, net | 32 | 25 | 17 | 7 | 591,000 | |
| Other income | 2 | 2 | 5 | 4 | 2 | |
| Income (loss) before income taxes | 139 | 258 | −51 | −213 | −168 | |
| Income tax (benefit) expense | −252 | 32 | 10 | 3 | 351,000 | |
| Consolidated net income | 391 | 226 | −61 | −216 | −168 | |
| Earnings (net loss) per share, Basic | 2.32 | 1.37 | −0.37 | −1.34 | −1.05 | |
| Earnings (net loss) per share, diluted | 2.3 | 1.36 | −0.37 | −1.34 | −1.05 | |
| Weighted average common shares outstanding, basic | 168 | 166 | 164 | 162 | 160,493 | |
| Weighted average common shares outstanding, diluted | 170 | 166 | 164 | 162 | 160,493 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 178 | 320 | 189 | 115 | 147 | |
| Investment securities, available-for-sale | 642 | 436 | 250 | 302 | 373 | |
| Accounts receivable, net | 121 | 99 | 98 | 62 | 64 | |
| Interest and other receivables | 27 | 6 | 4 | 885,000 | 978,000 | |
| Inventory | 35 | 22 | 36 | 7 | 8 | |
| Prepaid expenses | 60 | 56 | 39 | 21 | 24 | |
| Total current assets | 1,062 | 938 | 616 | 508 | 618 | |
| Property and equipment, net | 8 | 4 | 5 | 6 | 8 | |
| Operating lease right-of-use assets | 47 | 47 | 52 | 56 | 58 | |
| Intangible assets, net | 109 | 120 | 65 | 0 | — | |
| Restricted cash | 8 | 9 | 6 | 6 | 6 | |
| Long-term inventory | 77 | 70 | 5 | 5 | 6 | |
| Deferred tax assets | 250 | 0 | — | — | — | |
| Other assets | 4 | 359,000 | 476,000 | 8 | 4 | |
| Total assets | 1,564 | 1,188 | 749 | 588 | 700 | |
| Accounts payable | 11 | 16 | 18 | 13 | 7 | |
| Accrued liabilities | 266 | 379 | 237 | 113 | 89 | |
| Total current liabilities | 277 | 395 | 254 | 126 | 96 | |
| Operating lease liabilities | 41 | 42 | 48 | 53 | 56 | |
| Other long-term liabilities | 19 | 18 | 15 | 9 | 7 | |
| Total liabilities | 337 | 455 | 317 | 187 | 159 | |
| Commitments and contingencies (Note 9) | — | — | — | — | — | |
| Preferred stock, $0.0001 par value; 5,000,000 shares authorized at December 31, 2025 and 2024; no shares issued and outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value; 225,000,000 shares authorized at December 31, 2025 and 2024; 170,309,376 shares and 166,708,856 shares issued and outstanding at December 31, 2025 and 2024, respectively | 16,000 | 16,000 | 16,000 | 16,000 | 16,000 | |
| Additional paid-in capital | 3,039 | 2,937 | 2,863 | 2,771 | 2,695 | |
| Accumulated deficit | −1,813 | −2,204 | −2,431 | −2,370 | −2,154 | |
| Accumulated other comprehensive income | 1 | 292,000 | 24,000 | −975,000 | −192,000 | |
| Total stockholders equity | 1,227 | 733 | 432 | 400 | 541 | |
| Total liabilities and stockholders equity | 1,564 | 1,188 | 749 | 588 | 700 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net income (loss) | 391 | 226 | −61 | −216 | −168 | |
| Stock-based compensation | 52 | 67 | 66 | 68 | 64 | |
| Amortization of premiums and accretion of discounts on investment securities | −5 | −9 | −8 | −3 | 2 | |
| Amortization of intangible assets | 11 | 15 | 4 | 0 | 1 | |
| Gain on sale of non-financial asset | 0 | −147 | 0 | 0 | — | |
| Gain on strategic investment | 0 | 0 | −5 | −4 | −2 | |
| Depreciation | 900,000 | 900,000 | 2 | 2 | 2 | |
| Loss on sale of investment securities | 0 | 0 | 524,000 | 0 | 0 | |
| Deferred income taxes (including benefit from valuation allowance) | −250 | 0 | 0 | — | — | |
| Accounts receivable, net | −23 | −472,000 | −36 | 2 | −16 | |
| Interest and other receivables | −21 | −2 | −3 | 93,000 | 1 | |
| Inventory | −18 | −50 | −29 | 2 | −4 | |
| Prepaid expenses and other current assets | −4 | −17 | −18 | 2 | 2 | |
| Operating lease right-of-use assets | 9 | 8 | 6 | 7 | 6 | |
| Other assets | −3 | 117,000 | −33,000 | −48,000 | 10,000 | |
| Accounts payable | −5 | −1 | 5 | 6 | −2 | |
| Accrued liabilities | −19 | 71 | 93 | 24 | −8 | |
| Operating lease liabilities | −7 | −8 | −6 | −8 | −5 | |
| Long-term liabilities | 1 | 3 | 6 | 2 | 2 | |
| Net cash provided by operating activities | 110 | 158 | 17 | −114 | −126 | |
| Purchases of investment securities | −693 | −505 | −370 | −363 | −493 | |
| Sale and maturity of investment securities | 494 | 329 | 430 | 436 | 423 | |
| Proceeds from sale of non-financial asset | 0 | 147 | 0 | 0 | — | |
| Proceeds from sales of strategic investment | 0 | 0 | 12 | 0 | 0 | |
| Net purchases of property and equipment | −5 | −523,000 | −50,000 | 0 | −1 | |
| Payment of milestone and contingent payments in connection with asset acquisition | −99 | 0 | −40 | 0 | 0 | |
| Net cash (used in) provided by investing activities | −303 | −31 | 32 | 73 | −71 | |
| Proceeds from issuance of common stock, net of issuance costs | 50 | 7 | 25 | 8 | 18 | |
| Net cash provided by financing activities | 50 | 7 | 25 | 8 | 18 | |
| Effect of exchange rate changes on cash | 26,000 | −94,000 | −18,000 | 6,000 | 7,000 | |
| Net (decrease) increase in cash, cash equivalents and restricted cash | −143 | 134 | 74 | −33 | −179 | |
| Cash paid for income taxes | 25 | 20 | 6 | 2 | 1 | |
| Accrued inventory purchases | 1 | 1 | 0 | 0 | — | |
| Stock based compensation capitalized | 426,000 | 425,000 | 79,000 | — | — | |
| Accrued milestone and contingent payments in connection with asset acquisition | 0 | 99 | 30 | 0 | 0 |