ILLUMINA, INC.
Business
ILLUMINA, INC. develops and sells sequencing- and array-based solutions for genetic and genomic analysis worldwide. It offers sequencing platforms, microarrays, consumables (reagents, flow cells, library preparation kits), informatics and bioinformatics software, and services including whole-genome sequencing, genotyping, noninvasive prenatal testing (NIPT) and laboratory support. Its operations are organized as a single Core Illumina reportable segment following the spin-off of GRAIL, with GRAIL’s Galleri multi-cancer test referenced separately. Illumina markets and distributes products directly and through life-science distributors across North America, Europe, Latin America, China, and the Asia‑Pacific region.
Summary from filing dated 2025-02-12
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 4,343 | 4,372 | 4,504 | 4,584 | 4,526 | |
| Amortization of acquired intangible assets | 66 | 127 | 191 | 173 | 71 | |
| Total cost of revenue | 1,473 | 1,511 | 1,760 | 1,612 | 1,372 | |
| Gross profit | 2,870 | 2,861 | 2,744 | 2,972 | 3,154 | |
| Research and development | 967 | 1,169 | 1,354 | 1,321 | 1,185 | |
| Selling, general and administrative | 1,086 | 1,092 | 1,612 | 1,297 | 2,092 | |
| Goodwill and intangible impairment | 0 | 1,889 | 827 | 3,914 | 0 | |
| Legal contingency and settlement | 10 | −456 | 20 | 619 | 0 | |
| Total operating expense | 2,063 | 3,694 | 3,813 | 7,151 | 3,277 | |
| Income (loss) from operations | 807 | −833 | −1,069 | −4,179 | −123 | |
| Interest income | 40 | 46 | 58 | 11 | 0 | |
| Interest expense | −101 | −100 | −77 | −26 | — | |
| Other income (expense), net | 340 | −292 | −29 | −142 | 1,068 | |
| Total other income (expense), net | 279 | −346 | −48 | −157 | 1,007 | |
| Income (loss) before income taxes | 1,086 | −1,179 | −1,117 | −4,336 | 884 | |
| Provision for income taxes | 236 | 44 | 44 | 68 | 122 | |
| Net income (loss) | 850 | −1,223 | −1,161 | −4,404 | 762 | |
| Basic (in dollars per share) | 5.47 | −7.69 | −7.34 | −28 | 5.07 | |
| Diluted (in dollars per share) | 5.45 | −7.69 | −7.34 | −28 | 5.04 | |
| Basic (in shares) | 155 | 159 | 158 | 157 | 150 | |
| Diluted (in shares) | 156 | 159 | 158 | 157 | 151 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 1,418 | 1,127 | 1,048 | 2,011 | 1,232 | |
| Short-term investments | 215 | 93 | 6 | 26 | 107 | |
| Accounts receivable, net | 854 | 735 | 734 | 671 | 648 | |
| Inventory, net | 564 | 547 | 587 | 568 | 431 | |
| Prepaid expenses and other current assets | 238 | 244 | 234 | 285 | 295 | |
| Total current assets | 3,289 | 2,746 | 2,609 | 3,561 | 2,713 | |
| Property and equipment, net | 759 | 815 | 1,007 | 1,091 | 1,024 | |
| Operating lease right-of-use assets | 370 | 419 | 544 | 653 | 672 | |
| Goodwill | 1,113 | 1,113 | 2,545 | 3,239 | 7,113 | |
| Intangible assets, net | 210 | 295 | 2,993 | 3,285 | 3,250 | |
| Deferred tax assets, net | 454 | 567 | 56 | — | — | |
| Other assets | 449 | 348 | 357 | 423 | 445 | |
| Total assets | 6,644 | 6,303 | 10,111 | 12,252 | 15,217 | |
| Accounts payable | 240 | 221 | 245 | 293 | 332 | |
| Accrued liabilities | 846 | 827 | 1,325 | 1,232 | 761 | |
| Term debt, current portion | 499 | 499 | 0 | 500 | 0 | |
| Total current liabilities | 1,585 | 1,547 | 1,570 | 2,773 | 1,093 | |
| Operating lease liabilities | 486 | 554 | 687 | 744 | 774 | |
| Term debt | 1,490 | 1,490 | 1,489 | 1,487 | — | |
| Other long-term liabilities | 360 | 339 | 620 | 649 | 915 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, $0.01 par value, 10 million shares authorized; no shares issued and outstanding at December 28, 2025 and December 29, 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.01 par value, 320 million shares authorized; 201 million shares issued and 153 million outstanding at December 28, 2025; 200 million shares issued and 159 million outstanding at December 29, 2024 | 2 | 2 | 2 | 2 | 2 | |
| Additional paid-in capital | 7,822 | 7,525 | 9,555 | 9,207 | 8,938 | |
| Accumulated other comprehensive (loss) income | −10 | 22 | −1 | 3 | 17 | |
| Accumulated deficit | −392 | −1,242 | −19 | 1,142 | 5,485 | |
| Treasury stock, at cost; 48 million shares and 41 million shares at December 28, 2025 and December 29, 2024, respectively | −4,699 | −3,934 | −3,792 | −3,755 | −3,702 | |
| Total stockholders equity | 2,723 | 2,373 | 5,745 | 6,599 | 10,740 | |
| Total liabilities and stockholders equity | 6,644 | 6,303 | 10,111 | 12,252 | 15,217 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation expense | 203 | 224 | 235 | 215 | 176 | |
| Amortization of intangible assets | 67 | 130 | 197 | 179 | 75 | |
| Share-based compensation expense | 275 | 370 | 380 | 366 | 754 | |
| Deferred income taxes | 119 | −112 | −33 | −23 | −76 | |
| Net (gains) losses on strategic investments | −328 | 312 | 40 | 122 | −18 | |
| Change in fair value of contingent consideration liabilities | −18 | −315 | −24 | −205 | 4 | |
| Goodwill and intangible impairment | 23 | 1,889 | 827 | — | — | |
| Property and equipment and right-of-use asset impairment | 4 | 46 | 100 | 9 | 6 | |
| Non-cash charitable contribution | 19 | 0 | 0 | — | — | |
| Gain on Helix contingent value right | 0 | −15 | −10 | 7 | −30 | |
| Other | 18 | 14 | 17 | 8 | 23 | |
| Accounts receivable | −108 | −25 | −40 | −12 | −164 | |
| Inventory | −17 | 19 | −20 | −135 | −58 | |
| Prepaid expenses and other current assets | −8 | −14 | 11 | 16 | −64 | |
| Operating lease right-of-use assets and liabilities, net | −34 | −32 | −16 | −8 | −13 | |
| Other assets | −21 | −15 | 5 | 19 | −27 | |
| Accounts payable | 2 | −4 | −44 | −38 | 60 | |
| Accrued liabilities | 0 | −440 | 15 | 381 | 101 | |
| Other long-term liabilities | 33 | 28 | −1 | −19 | 13 | |
| Net cash provided by operating activities | 1,079 | 837 | 478 | 392 | 545 | |
| Net purchases of property and equipment | −148 | −128 | −195 | −286 | −208 | |
| Net sales (purchases) of strategic investments | 103 | −52 | −6 | −40 | 246 | |
| Cash paid for acquisitions and intangible assets, net of cash acquired | −10 | −81 | −30 | −265 | −2,444 | |
| Cash received for Helix contingent value right | 0 | 83 | 0 | 0 | — | |
| Net cash used in investing activities | −55 | −178 | −231 | −591 | −1,069 | |
| Common stock repurchases | −742 | −116 | 0 | 0 | 0 | |
| Taxes paid related to net share settlement of equity awards | −40 | −32 | −40 | −54 | −511 | |
| Proceeds from issuance of common stock | 44 | 56 | 67 | 63 | 60 | |
| Payments on contingent consideration liabilities | −1 | −1 | −1 | 0 | — | |
| Proceeds from debt, net of issuance costs | — | — | −1 | — | — | |
| Proceeds from debt, net of issuance costs | 495 | 1,241 | 0 | 991 | 988 | |
| Payments on debt obligations | −500 | −750 | −1,235 | 0 | −517 | |
| GRAIL cash deconsolidated as a result of spin-off | 0 | −968 | 0 | 0 | — | |
| Net cash used in financing activities | −744 | −570 | −1,210 | 1,000 | −51 | |
| Effect of exchange rate changes on cash and cash equivalents | 11 | −10 | 0 | −22 | −3 | |
| Net increase (decrease) in cash and cash equivalents | 291 | 79 | −963 | 779 | −578 | |
| Cash paid for interest | 95 | 83 | 73 | 17 | 9 | |
| Cash paid for income taxes (see Note 10) | 73 | 105 | 65 | 122 | 233 | |
| Cash paid for operating lease liabilities | 114 | 132 | 123 | 112 | 96 | |
| Purchases of property and equipment included in accounts payable and accrued liabilities | 22 | 4 | 12 | 16 | — | |
| GRAIL net assets, excluding cash and cash equivalents, deconsolidated as a result of spin-off | 0 | 1,770 | 0 | — | — |