MACROGENICS INC
Business
MacroGenics Inc is a clinical-stage biopharmaceutical company that discovers, develops, manufactures and commercializes innovative antibody-based therapeutics for the treatment of cancer. It develops multi-specific antibody platforms (DART and TRIDENT), antibody‑drug conjugates (ADCs), and related monoclonal antibody programs, and provides outsourced contract development and commercial manufacturing services. Its business is organized around wholly owned clinical and preclinical pipeline programs, partnered and out‑licensed products, and its manufacturing/CDMO operations. It advances programs and distributes products through collaborations, partner arrangements and regulatory approvals in the U.S. and international markets.
Summary from filing dated 2025-03-20
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 150 | 150 | 59 | 152 | 77 | |
| Cost of product sales | 0 | 847,000 | 619,000 | 3 | 3 | |
| Cost of manufacturing services | 36 | 11 | 8 | 4 | 0 | |
| Research and development | 147 | 177 | 167 | 207 | 215 | |
| Selling, general and administrative | 39 | 71 | 52 | 59 | 63 | |
| Total costs and expenses | 222 | 261 | 227 | 273 | 280 | |
| Loss from operations | −73 | −111 | −168 | −121 | −203 | |
| Gain on royalty monetization arrangement | 0 | 0 | 151 | 0 | 0 | |
| Gain on sale of MARGENZA | 0 | 36 | 0 | 0 | — | |
| Interest and other income | 6 | 9 | 10 | 2 | 680,000 | |
| Interest and other expense | −9 | −1 | −1 | — | — | |
| Loss before income taxes | −75 | −66 | −9 | −120 | — | |
| Income tax (benefit) expense | −700,000 | 944,000 | 0 | 0 | — | |
| Net loss | −75 | −67 | −9 | −120 | −202 | |
| Unrealized gain (loss) on investments | 28,000 | 10,000 | −1,000 | 56,000 | −54,000 | |
| Comprehensive loss | −75 | −67 | −9 | −120 | −202 | |
| Basic and diluted net loss per common share, basic (in dollars per share) | −1.18 | −1.07 | −0.15 | −1.95 | −3.37 | |
| Basic and diluted net loss per common share, diluted (in dollars per share) | −1.18 | −1.07 | −0.15 | −1.95 | −3.37 | |
| Basic weighted average number of common shares outstanding (in shares) | 63 | 63 | 62 | 61 | 60 | |
| Diluted weighted average number of common shares outstanding (in shares) | 63 | 63 | 62 | 61 | 60 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 57 | 183 | 101 | 109 | 123 | |
| Marketable securities | 133 | 19 | 129 | 46 | 120 | |
| Accounts receivable | 13 | 4 | 10 | 56 | 10 | |
| Inventory, net | 8 | 0 | 1 | 1 | 4 | |
| Prepaid expenses and other current assets | 9 | 12 | 10 | 10 | 21 | |
| Total current assets | 220 | 217 | 251 | 222 | 280 | |
| Property, equipment and software, net | 13 | 18 | 22 | 30 | 38 | |
| Operating lease right-of-use assets | 23 | 25 | 24 | 27 | 17 | |
| Other non current assets | 1 | 2 | 1 | 1 | 1 | |
| Total assets | 257 | 262 | 298 | 280 | 335 | |
| Accounts payable | 5 | 5 | 6 | 5 | 16 | |
| Accrued expenses and other current liabilities | 22 | 29 | 24 | 29 | 34 | |
| Deferred revenue | 11 | 16 | 22 | 10 | 21 | |
| Lease liabilities | 5 | 5 | 4 | 5 | 5 | |
| Total current liabilities | 43 | 56 | 56 | 49 | 75 | |
| Liability related to future royalties | 70 | 0 | — | — | — | |
| Deferred revenue, net of current portion | 56 | 56 | 59 | 59 | 0 | |
| Lease liabilities, net of current portion | 32 | 33 | 30 | 30 | 21 | |
| Other non current liabilities | 1 | 2 | 258,000 | 258,000 | 258,000 | |
| Total liabilities | 201 | 146 | 146 | 138 | 96 | |
| Common stock, 0.01 par value -- 125,000,000 shares authorized, 63,318,613 and 62,819,857 shares outstanding at December 31, 2025 and December 31, 2024, respectively | 633,000 | 628,000 | 621,000 | 617,000 | 613,000 | |
| Additional paid-in capital | 1,299 | 1,285 | 1,255 | 1,235 | 1,213 | |
| Accumulated other comprehensive gain | 32,000 | 4,000 | −6,000 | −5,000 | −61,000 | |
| Accumulated deficit | −1,244 | −1,170 | −1,103 | −1,094 | −974 | |
| Total stockholders' equity | 56 | 116 | 153 | 142 | 240 | |
| Total liabilities and stockholders' equity | 257 | 262 | 298 | 280 | 335 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 7 | 8 | 10 | 12 | 11 | |
| Amortization of premiums and discounts on marketable securities | −2 | −3 | −5 | 403,000 | 2 | |
| Share-based compensation | 14 | 29 | 18 | 20 | 23 | |
| Non-cash royalty revenue | −8 | 0 | 0 | — | — | |
| Non-cash interest expense | 8 | 0 | 1 | 0 | 0 | |
| Non-cash lease expense | 2 | −663,000 | 3 | 3 | 3 | |
| Other non-cash items | 0 | 2,000 | 423,000 | 3 | 2 | |
| (Gain) loss on disposal of assets | −10,000 | −57,000 | 111,000 | 0 | 0 | |
| Accounts receivable | −9 | 6 | 46 | −46 | 13 | |
| Inventory | −8 | −2 | 230,000 | 55,000 | −6 | |
| Prepaid expenses and other current assets | 3 | −2 | 215,000 | 11 | −4 | |
| Other non current assets | 0 | −170,000 | −7,000 | −14 | 3 | |
| Accounts payable | −280,000 | −2 | 1 | −11 | 7 | |
| Accrued expenses and other current liabilities | −7 | 5 | −5 | −5 | −607,000 | |
| Lease liabilities | −699,000 | 3 | −861,000 | 9 | −4 | |
| Deferred revenue | −5 | −9 | 11 | 49 | 9 | |
| Other non current liabilities | −916,000 | 2 | 0 | 0 | — | |
| Net cash used in operating activities | −81 | −68 | −78 | −87 | −144 | |
| Purchases of marketable securities | −208 | −77 | −240 | −121 | −231 | |
| Proceeds from sales and maturities of marketable securities | 96 | 190 | 161 | 195 | 201 | |
| Purchases of property, equipment and software | −2 | −4 | −2 | −4 | −6 | |
| Proceeds from sale of MARGENZA | 0 | 40 | 0 | 0 | — | |
| Proceeds from sales of equipment | 11,000 | 160,000 | 64,000 | 0 | 0 | |
| Net cash provided by (used in) investing activities | −114 | 149 | −80 | 71 | −37 | |
| Proceeds from issuance of common stock, net of offering costs | 0 | 0 | 616,000 | 1 | 118 | |
| Proceeds from stock option exercises and ESPP purchases | 129,000 | 3 | 553,000 | 574,000 | 5 | |
| Taxes paid related to net share settlement of equity awards | −288,000 | −2 | −306,000 | 0 | — | |
| Principal payments on royalty monetization arrangement | 0 | 0 | −157,000 | 0 | 0 | |
| Net proceeds from sale of future royalties | 70 | 0 | 150 | 0 | 0 | |
| Net cash provided by financing activities | 70 | 960,000 | 150 | 2 | 123 | |
| Net change in cash and cash equivalents | −126 | 82 | −8 | −15 | −58 | |
| Property and equipment included in accounts payable or accruals | 54,000 | 100,000 | 505,000 | 118,000 | 508,000 |