Xencor Inc
Business
Xencor Inc is a clinical-stage biopharmaceutical company focused on discovering and developing engineered antibody therapeutics to treat cancer and autoimmune diseases using proprietary protein engineering capabilities and XmAb Fc domain technology. The company advances multiple wholly-owned bispecific and multi-specific antibody candidates through Phase 1 and Phase 2 clinical studies, including oncology programs (XmAb819, XmAb541, XmAb808) and autoimmune disease programs (XmAb942, plamotamab, XmAb657). Xencor generates revenue through product licenses, novel bispecific antibody collaborations, and technology licensing agreements with major pharmaceutical partners including Incyte, Amgen, Astellas, Johnson & Johnson, Alexion, and others, while retaining rights to internally develop certain prioritized programs.
Summary from 10-K filed 2026-02-25
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Collaborations, milestones, and royalties | 126 | 110 | 175 | 165 | 275 | |
| Research and development | 239 | 228 | 254 | 200 | 193 | |
| General and administrative | 64 | 61 | 53 | 47 | 39 | |
| Total operating expenses | 303 | 289 | 307 | 247 | 231 | |
| Operating loss | −178 | −178 | −132 | −82 | 44 | |
| Interest income | 28 | 32 | 19 | — | — | |
| Interest expense | −32 | −37 | −6 | −13,000 | — | |
| Gain (loss) on marketable equity securities, net | 102 | −31 | −395,000 | 23 | 39 | |
| Asset impairment charges | −9 | −20 | 0 | — | — | |
| Other, net | −73,000 | 50,000 | −31,000 | −148,000 | −1 | |
| Total other income (expense) | 88 | −57 | 13 | 28 | 39 | |
| Loss before income tax expense and noncontrolling interest | −90 | −235 | −120 | −55 | 83 | |
| Income tax expense | 3 | 2 | 14 | 700,000 | 0 | |
| Net loss including noncontrolling interest | −92 | −237 | −133 | −55 | 83 | |
| Net loss attributable to noncontrolling interest | −214,000 | −4 | −163,000 | 0 | 0 | |
| Net loss attributable to Xencor, Inc. | −92 | −233 | −133 | −55 | 83 | |
| Net loss per share attributable to Xencor, Inc. - basic (in dollars per share) | −1.24 | −3.58 | −2.2 | −0.93 | 1.42 | |
| Net loss per share attributable to Xencor, Inc. - diluted (in dollars per share) | −1.24 | −3.58 | −2.2 | −0.93 | 1.37 | |
| Weighted-average shares used in calculating net loss per share - basic (in shares) | 74 | 65 | 61 | 60 | 58 | |
| Weighted-average shares used in calculating net loss per share - diluted (in shares) | 74 | 65 | 61 | 60 | 60 | |
| Net unrealized gain (loss) on marketable debt securities | 2 | −2 | 8 | — | — | |
| Comprehensive loss | −90 | −238 | −125 | — | — | |
| Less: comprehensive loss attributable to the noncontrolling interest | −214,000 | −4 | −163,000 | — | — | |
| Comprehensive loss attributable to Xencor, Inc. | −90 | −235 | −125 | −61 | 81 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 54 | 41 | 54 | 54 | 143 | |
| Marketable debt securities | 381 | 409 | 498 | 527 | 154 | |
| Marketable equity securities | 113 | 48 | 42 | 42 | 37 | |
| Accounts receivable | 29 | 61 | 24 | 29 | 66 | |
| Prepaid expenses and other current assets | 23 | 19 | 18 | 23 | 24 | |
| Total current assets | 600 | 578 | 636 | 675 | 424 | |
| Restricted cash | 289,000 | 387,000 | 380,000 | 0 | — | |
| Marketable debt securities - long term | 176 | 257 | 146 | 4 | 300 | |
| Property and equipment, net | 53 | 60 | 66 | 59 | 28 | |
| Right-of-use assets | 38 | 38 | 34 | 34 | 32 | |
| Patents, licenses, and other intangible assets, net | 8 | 18 | 19 | 19 | 16 | |
| Other assets | 498,000 | 498,000 | 648,000 | 613,000 | 653,000 | |
| Total assets | 875 | 952 | 965 | 846 | 838 | |
| Accounts payable | 11 | 17 | 14 | 10 | 14 | |
| Accrued expenses | 35 | 19 | 24 | 19 | 19 | |
| Income tax payable | 4 | 0 | 5 | 0 | — | |
| Lease liabilities | 3 | 3 | 3 | 5 | 0 | |
| Liabilities related to the sales of future royalties | 43 | 48 | 28 | 0 | — | |
| Total current liabilities | 96 | 87 | 74 | 64 | 71 | |
| Long-term tax liabilities | 3 | 10 | — | — | — | |
| Lease liabilities, net of current portion | 65 | 65 | 59 | 55 | 34 | |
| Liabilities related to the sales of future royalties, net of current portion | 76 | 115 | 162 | 0 | — | |
| Total liabilities | 240 | 278 | 303 | 119 | 105 | |
| Commitments and contingencies | — | — | — | — | — | |
| Common stock, $0.01 par value: Authorized 200,000 shares Issued and outstanding 71,872 and 70,256 shares at December 31, 2025 and 2024, respectively | 718,000 | 703,000 | 611,000 | 601,000 | 595,000 | |
| Additional paid-in capital | 1,429 | 1,382 | 1,131 | 1,072 | 1,018 | |
| Accumulated other comprehensive income (loss) | 2 | −663,000 | 1 | −7 | −2 | |
| Accumulated deficit | −796 | −704 | −471 | −338 | −283 | |
| Total stockholders equity attributable to Xencor, Inc. | 636 | 678 | 662 | 727 | 734 | |
| Noncontrolling interest | 0 | −4 | 337,000 | 0 | — | |
| Total noncontrolling interest and stockholders equity | 636 | 674 | 662 | 727 | 734 | |
| Total liabilities and stockholders equity | 875 | 952 | 965 | 846 | 838 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 11 | 12 | 11 | 9 | 7 | |
| Accretion of discount on marketable debt securities, net | −3 | −16 | −14 | 127,000 | 3 | |
| Stock-based compensation | 43 | 53 | 54 | 49 | 37 | |
| Gain on sale of marketable securities, net | −14 | −37,000 | 0 | — | — | |
| Change in fair value of marketable equity securities | −87 | 31 | 395,000 | −5 | −2 | |
| Non-cash royalty revenue related to the sale of future royalties | −80 | −67 | −15 | — | — | |
| Non-cash interest expense on liabilities related to the sale of future royalties | 32 | 37 | 6 | — | — | |
| Equity received in connection with license agreement | 0 | 0 | −10 | −5 | −22 | |
| Abandonment of capitalized intangibles | 0 | 2 | 1 | 2 | 900,000 | |
| Loss on disposal of assets | 0 | 2 | 1 | 145,000 | 462,000 | |
| Accounts receivable | 29 | −33 | 20 | — | — | |
| Interest receivable from marketable debt securities | 3 | −3 | −1 | −530,000 | 655,000 | |
| Prepaid expenses and other assets | 9 | 159,000 | 5 | 634,000 | −14 | |
| Accounts payable | −4 | 3 | 4 | −4 | 5 | |
| Accrued expenses | 14 | −4 | 5 | −715,000 | 2 | |
| Income taxes | 4 | −4 | 14 | — | — | |
| Operating lease, net | 400,000 | 2 | 3 | 23 | 1 | |
| Deferred revenue | 0 | 0 | −30 | −7 | −55 | |
| Other assets and liabilities, net | −7 | 0 | 0 | — | — | |
| Net cash used in operating activities | −135 | −202 | −78 | 24 | −17 | |
| Purchase of marketable debt securities | −299 | −595 | −783 | −388 | −510 | |
| Purchase of property and equipment | −3 | −6 | −18 | −38 | −13 | |
| Purchase of patents | 0 | −3 | −3 | −5 | −3 | |
| Proceeds from sales of marketable equity securities | 37 | 7 | 0 | 0 | — | |
| Proceeds from sales and maturities of marketable debt securities | 405 | 590 | 693 | 307 | 485 | |
| Proceeds from sale of property and equipment | 0 | 0 | 1,000 | 0 | 19,000 | |
| Net cash provided by (used in) investing activities | 140 | −8 | −111 | −120 | −46 | |
| Proceeds from the exercises of stock options | 9 | 6 | 3 | 4 | 12 | |
| Proceeds from issuance of common stock under the Employee Stock Purchase Plan | 1 | 2 | 2 | 2 | 2 | |
| Proceeds from issuance of common stock and pre-funded warrants | 0 | 201 | 0 | 0 | 29 | |
| Common stock and pre-funded warrants issuance costs | 0 | −12 | 0 | 0 | — | |
| Proceeds from the sale of future royalties | 0 | 0 | 183 | 0 | 0 | |
| Proceeds from noncontrolling interest | 0 | 0 | 500,000 | 0 | 0 | |
| Cash paid to acquire noncontrolling interest | −2 | 0 | 0 | — | — | |
| Net cash provided by financing activities | 8 | 197 | 189 | 6 | 43 | |
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 13 | −13 | 228,000 | −90 | −20 | |
| Interest paid | 5,000 | 33,000 | 22,000 | 13,000 | 14,000 | |
| Income taxes paid | 7 | 6 | 0 | 700,000 | 0 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Xencor Inc's CIK number?
Xencor Inc's SEC CIK number is 0001326732 (1326732). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Xencor Inc's SEC filings?
All of Xencor Inc's EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Xencor Inc last report earnings?
Xencor Inc (XNCR) most recently filed an earnings 8-K with the SEC on May 6, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001326732-26-000042). This is Xencor Inc's most recent earnings filing of record — not a forecast of its next earnings date.
What is Xencor Inc's most recent earnings 8-K?
Xencor Inc's latest earnings 8-K (Item 2.02) was filed May 6, 2026 under accession 0001326732-26-000042. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Xencor Inc's latest earnings 8-K →
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