PRECIGEN, INC.
Business
PRECIGEN, INC. is a discovery and clinical-stage biopharmaceutical company developing next-generation gene and cell therapies aimed at addressing unmet needs in immuno-oncology, autoimmune disorders, and infectious diseases. It offers product candidates and platform technologies including UltraCAR-T cell therapies, AdenoVerse gorilla adenovector immunotherapies, ActoBiotics microbe-based therapeutics, and the UltraPorator electroporation manufacturing device. The company reports two operating segments: Biopharmaceuticals (including Precigen and ActoBio) and Exemplar (MiniSwine research models and services). It distributes investigational therapies through clinical trials, collaborations with institutions such as the NCI, internal cGMP manufacturing, and commercial channels as programs progress toward approval.
Summary from filing dated 2025-03-19
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 10 | 4 | 6 | 27 | 14 | |
| Research and development | 41 | 53 | 49 | — | — | |
| Selling, general and administrative | 70 | 41 | 40 | — | — | |
| Impairment of goodwill | 4 | 7 | 10 | 482,000 | 0 | |
| Impairment of other noncurrent assets | 0 | 33 | 445,000 | 638,000 | 543,000 | |
| Total operating expenses | 120 | 139 | 106 | — | — | |
| Operating loss | −111 | −135 | −100 | — | — | |
| Change in fair value of warrant liabilities | −140 | 0 | 0 | — | — | |
| Interest expense | −4 | −6,000 | −468,000 | — | — | |
| Interest income | 3 | 1 | 3 | — | — | |
| Other income, net | 43,000 | 6 | 627,000 | — | — | |
| Total other (expense) income, net | −140 | 7 | 3 | — | — | |
| Loss before income taxes | −251 | −128 | −96 | −80 | −111 | |
| Income tax (expense) benefit | −3,000 | 2 | 458,000 | 189,000 | 160,000 | |
| Net loss | −251 | −126 | −96 | 28 | −92 | |
| Deemed dividend on preferred stock | −179 | 0 | 0 | — | — | |
| Net loss attributable to common shareholders | −430 | −126 | −96 | — | — | |
| Net loss per share attributable to common shareholders, basic (in dollars per share) | −1.37 | −0.47 | −0.39 | 0.14 | −0.47 | |
| Net loss per share attributable to common shareholders, diluted (in dollars per share) | −1.37 | −0.47 | −0.39 | 0.14 | −0.47 | |
| Weighted average shares outstanding, basic (in shares) | 313 | 268 | 245 | 200 | 198 | |
| Weighted average shares outstanding, diluted (in shares) | 313 | 268 | 245 | 200 | 198 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 30 | 30 | 8 | 5 | 36 | |
| Short-term investments | 68 | 68 | 55 | 51 | 72 | |
| Trade, less allowance for credit losses of $0 as of December 31, 2025 and 2024. | 4 | 926,000 | 902,000 | 978,000 | 1 | |
| Other | 446,000 | 237,000 | 673,000 | 13 | 566,000 | |
| Inventory | 10 | 0 | — | 287,000 | 326,000 | |
| Prepaid expenses and other | 3 | 3 | 4 | 5 | 5 | |
| Total current assets | 115 | 102 | 69 | 118 | 157 | |
| Long-term investments | 3 | 0 | — | 0 | 49 | |
| Property, plant and equipment, net | 14 | 14 | 7 | 7 | 9 | |
| Intangible assets, net | 3 | 4 | 41 | 44 | 52 | |
| Goodwill | 15 | 19 | 27 | 37 | 38 | |
| Right-of-use assets | 5 | 5 | 7 | 8 | 10 | |
| Other assets | 908,000 | 371,000 | 767,000 | 1 | 936,000 | |
| Total assets | 156 | 145 | 151 | 216 | 360 | |
| Accounts payable | 12 | 4 | 2 | 4 | 3 | |
| Accrued compensation and benefits | 10 | 8 | 8 | 6 | 8 | |
| Other accrued liabilities | 11 | 5 | 6 | 5 | 8 | |
| Indemnification accrual | 2 | 3 | 5 | — | — | |
| Deferred revenue | 517,000 | 589,000 | 509,000 | 25,000 | 1 | |
| Current portion of lease liabilities | 1 | 956,000 | 1 | 1 | 1 | |
| Total current liabilities | 37 | 22 | 23 | 79 | 35 | |
| Long-term debt | 93 | 0 | — | 0 | 180 | |
| Deferred revenue, net of current portion | 0 | 2 | 2 | 2 | 23 | |
| Lease liabilities, net of current portion | 4 | 5 | 6 | 7 | 9 | |
| Other long-term liabilities | 134,000 | 0 | — | — | 50,000 | |
| Warrant liabilities | 0 | 51 | — | — | — | |
| Total liabilities | 135 | 79 | 33 | 90 | 253 | |
| Commitments and contingencies (Note 15) | — | — | — | — | — | |
| Series A Preferred Stock, no par value, 81,000 shares authorized as of December 31, 2025 and December 31, 2024; zero and 79,000 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively (aggregate liquidation preference of zero as of December 31, 2025 and $79,000 as of December 31, 2024). | 0 | 28 | 0 | 0 | — | |
| Common stock, no par value, 700,000,000 shares authorized as of December 31, 2025 and 400,000,000 authorized as of December 31, 2024; 353,910,926 shares and 292,869,097 shares issued as of December 31, 2025 and 2024, 353,910,926 shares and 292,869,097 shares outstanding as of December 31, 2025 and 2024, respectively. | 0 | 0 | 0 | 0 | 0 | |
| Additional paid-in capital | 2,362 | 2,129 | 2,085 | 1,998 | 2,023 | |
| Accumulated deficit | −2,341 | −2,091 | −1,964 | −1,869 | −1,916 | |
| Accumulated other comprehensive income | 7,000 | 12,000 | −2 | −3 | 203,000 | |
| Total shareholders' equity | 21 | 39 | 118 | 126 | 107 | |
| Total liabilities, mezzanine equity and shareholders' equity | 156 | 145 | 151 | 216 | 360 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 3 | 5 | 7 | 11 | 14 | |
| Gain (Loss) on disposals of assets, net | 14,000 | −2,000 | −72,000 | 421,000 | — | |
| Gain on debt retirement | 0 | 0 | −60,000 | −961,000 | 0 | |
| Loss on reclassification of cumulative foreign currency translation adjustments | 0 | 3 | 0 | 0 | 0 | |
| Change in fair value of warrant liabilities | 140 | 0 | 0 | — | — | |
| Amortization of discounts on investments, net | −2 | −883,000 | −2 | 832,000 | 1 | |
| Stock-based compensation expense | 11 | 9 | 10 | 10 | 14 | |
| Shares issued as payment for services | 527,000 | 553,000 | 545,000 | 575,000 | 577,000 | |
| Accretion of debt discount and amortization of deferred financing costs | 356,000 | 0 | 60,000 | 1 | 12 | |
| Total deferred tax (benefit) | 0 | −2 | −479,000 | −150,000 | −167,000 | |
| Issuance cost related to Warrants | 0 | 292,000 | 0 | 0 | — | |
| Other noncash items | 0 | 0 | 2,000 | 107,000 | 24,000 | |
| Trade | −3 | −24,000 | 76,000 | −2 | −6 | |
| Other | −209,000 | 438,000 | 12 | −11 | −330,000 | |
| Inventory | −9 | 0 | 0 | 2 | −2 | |
| Prepaid expenses and other | −93,000 | 981,000 | 748,000 | 3 | −1 | |
| Other assets | −556,000 | 120,000 | 129,000 | −101,000 | 305,000 | |
| Accounts payable | 9 | 2 | −2 | 379,000 | 420,000 | |
| Accrued compensation and benefits | 7 | 3 | 5 | −37,000 | 3 | |
| Other accrued liabilities | 7 | −2 | 782,000 | −2 | 2 | |
| Deferred revenue | −2 | 196,000 | 484,000 | −23 | 2 | |
| Lease liabilities | −9,000 | −55,000 | −107,000 | −107,000 | 97,000 | |
| Other long-term liabilities | 134,000 | 0 | 0 | −37,000 | −50,000 | |
| Indemnification Accruals | −737,000 | −2 | −14 | 13 | — | |
| Net cash used in operating activities | −88 | −68 | −67 | −65 | −56 | |
| Purchases of investments | −208 | −187 | −185 | 0 | −174 | |
| Sales and maturities of investments | 208 | 175 | 183 | 68 | 100 | |
| Purchases of property, plant and equipment | −2 | −9 | −2 | −5 | −7 | |
| Proceeds from sale of assets | 0 | 60,000 | 98,000 | 594,000 | 3 | |
| Net cash used in investing activities | −2 | −21 | −3 | 226 | −75 | |
| (Payments) Proceeds from issuance of common stock, net of issuance costs | −355,000 | 31 | 73 | 0 | — | |
| Proceeds from long-term debt, net of issuance costs | 93 | 0 | 0 | — | 0 | |
| Payments of long-term debt, including cost to retire of $120 in 2023 | 0 | 0 | −43 | −155 | −466,000 | |
| (Payments) Proceeds from issuance of Series A Preferred Stock and Warrants, net of issuance cost | −537,000 | 79 | 0 | 0 | — | |
| Cash Settlement of Performance Stock Units | −1 | 0 | 0 | — | — | |
| Payments to taxing authorities in connection with shares directly withheld from employees | −2 | 0 | 0 | — | — | |
| Proceeds from stock option exercises | 1 | 346,000 | 0 | 1,000 | — | |
| Net cash provided by financing activities | 90 | 111 | 30 | −155 | 121 | |
| Effect of exchange rate changes on cash, cash equivalents, and restricted cash | 35,000 | −27,000 | −320,000 | −827,000 | 217,000 | |
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 717,000 | 22 | −41 | 5 | −9 | |
| Cash paid during the period for interest | 4 | 7,000 | 1 | 9 | 7 | |
| Cash paid during the period for income taxes | 3,000 | 4,000 | 21,000 | 0 | 36,000 | |
| Accrued compensation paid in equity awards | 4 | 3 | 3 | 2 | — | |
| Conversion of preferred stock to common stock | 210 | 0 | 0 | — | — | |
| Settlement of warrants to equity | 190 | 0 | 0 | — | — | |
| Purchases of property and equipment included in accounts payable and other accrued liabilities | 214,000 | 341,000 | 566,000 | 40,000 | 820,000 | |
| Issuance costs included in accounts payable and other accrued liabilities | 0 | 892,000 | 0 | 0 | — |