ANAPTYSBIO, INC
Business
Anaptysbio is a clinical-stage biotechnology company developing immunology therapeutics for autoimmune and inflammatory diseases. The company's pipeline includes rosnilimab (selective pathogenic T cell depleter, Phase 2b in rheumatoid arthritis), ANB033 (CD122 antagonist, Phase 1b in celiac disease and eosinophilic esophagitis), and ANB101 (BDCA2 modulator, Phase 1a). Anaptysbio also monetizes value from out-licensed programs: Jemperli (dostarlimab, PD-1 antagonist) partnered with GSK generating royalties, and imsidolimab (IL-36R antagonist) partnered with Vanda generating milestones and royalties.
Summary from 10-K filed 2026-03-03
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Collaboration revenue | 235 | 91 | 17 | 10 | 63 | |
| Research and development | 136 | 164 | 132 | 89 | 98 | |
| General and administrative | 51 | 42 | 42 | 37 | 21 | |
| Acquired in-process research and development | 0 | 0 | 7 | 0 | 0 | |
| Total operating expenses | 187 | 206 | 182 | 125 | 120 | |
| Income (loss) from operations | 48 | −115 | −164 | −115 | −57 | |
| Interest income | 13 | 20 | 19 | 8 | 431,000 | |
| Non-cash interest expense for the sale of future royalties | −80 | −50 | −18 | −21 | −1 | |
| Other income (expense), net | 5 | 14,000 | −2,000 | 12,000 | 37,000 | |
| Total other (expense) income, net | −61 | −30 | 788,000 | −14 | −982,000 | |
| Loss before income taxes | −13 | −145 | −164 | −129 | −58 | |
| (Provision) benefit for income taxes | −164,000 | −3,000 | 4,000 | −24,000 | 0 | |
| Net loss | −13 | −145 | −164 | −129 | −58 | |
| Unrealized (loss) gain on available for sale securities | −329,000 | 1 | 4 | −5 | — | |
| Comprehensive loss | −14 | −144 | −159 | −134 | −58 | |
| Basic (in dollars per share) | −0.46 | −5.12 | −6.08 | −4.57 | −2.11 | |
| Diluted (in dollars per share) | −0.46 | −5.12 | −6.08 | −4.57 | −2.11 | |
| Basic (in shares) | 29 | 28 | 27 | 28 | 27 | |
| Diluted (in shares) | 29 | 28 | 27 | 28 | 27 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 238 | 123 | 36 | 71 | 496 | |
| Receivables from collaborative partners | 34 | 41 | 7 | 1 | 876,000 | |
| Short-term investments | 73 | 262 | 355 | 370 | 52 | |
| Prepaid expenses and other current assets | 5 | 6 | 9 | 5 | 5 | |
| Total current assets | 350 | 432 | 407 | 447 | 554 | |
| Property and equipment, net | 1 | 2 | 2 | 2 | 2 | |
| Operating lease right-of-use assets | 13 | 14 | 16 | 18 | 20 | |
| Long-term investments | 0 | 35 | 27 | 143 | 67 | |
| Other long-term assets | 256,000 | 256,000 | 256,000 | 256,000 | 256,000 | |
| Total assets | 364 | 484 | 452 | 610 | 643 | |
| Accounts payable | 4 | 4 | 5 | 3 | 2 | |
| Accrued expenses | 33 | 40 | 31 | 22 | 13 | |
| Current portion of operating lease liability | 2 | 2 | 2 | 2 | 2 | |
| Total current liabilities | 39 | 45 | 37 | 26 | 16 | |
| Liability related to sale of future royalties | 277 | 353 | 311 | 304 | 251 | |
| Operating lease liability, net of current portion | 12 | 14 | 16 | 18 | 19 | |
| Preferred stock, $0.001 par value, 10,000 shares authorized and no shares, issued or outstanding at December 31, 2025 and December 31, 2024, respectively | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.001 par value, 500,000 shares authorized, 28,019 shares and 30,473 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 28,000 | 30,000 | 27,000 | 29,000 | 28,000 | |
| Additional paid in capital | 810 | 830 | 703 | 718 | 679 | |
| Accumulated other comprehensive (loss) gain | −24,000 | 305,000 | −797,000 | −5 | −422,000 | |
| Accumulated deficit | −773 | −759 | −614 | −450 | −322 | |
| Total stockholders equity | 37 | 71 | 88 | 262 | 356 | |
| Total liabilities and stockholders equity | 364 | 484 | 452 | 610 | 643 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization | 559,000 | 606,000 | 652,000 | 675,000 | 619,000 | |
| Stock-based compensation | 36 | 34 | 33 | 27 | 15 | |
| Accretion/amortization of investments, net | −5 | −10 | −11 | −3 | 493,000 | |
| Amortization of right-of-use assets operating | 2 | 2 | 2 | 2 | 1 | |
| Receivables from collaborative partners | 7 | −34 | −5 | −543,000 | −876,000 | |
| Prepaid expenses and other assets | 2 | 3 | −4 | −813,000 | −2 | |
| Accounts payable and other liabilities | −87 | −34 | 11 | 10 | −5 | |
| Operating lease liabilities | −2 | −2 | −2 | −2 | −72,000 | |
| Net cash provided by (used in) operating activities | 20 | −135 | −121 | −74 | −46 | |
| Purchase of investments | −196 | −380 | −304 | −803 | −119 | |
| Sales and maturities of investments | 425 | 476 | 449 | 408 | 159 | |
| Purchases of property and equipment | −87,000 | −358,000 | −807,000 | −358,000 | −1 | |
| Net cash provided by investing activities | 228 | 95 | 145 | −395 | 39 | |
| Proceeds from public offerings, net of underwriters' fees | 0 | 94 | 0 | 0 | — | |
| Proceeds from issuance of common stock | 14 | 6 | 2 | 12 | 3 | |
| Proceeds from the sale of future royalties | 0 | 50 | 0 | 35 | 250 | |
| Principal repayment of liability for sale of future royalties | −77 | −15 | −12 | −2 | 0 | |
| Payments for repurchase of common stock | −69 | −456,000 | −50 | 0 | 0 | |
| Payment for net share settlement of equity awards | −1 | −8 | 0 | 0 | — | |
| Payments for offering costs, net | 0 | −492,000 | 0 | 0 | — | |
| Payments for issuance costs related to the sale of future royalties | 0 | −103,000 | −43,000 | −336,000 | −255,000 | |
| Net cash (used in) provided by financing activities | −133 | 127 | −59 | 44 | 252 | |
| Net increase (decrease) in cash and cash equivalents | 115 | 87 | −35 | −424 | 245 | |
| Interest portion of repayment for sale of future royalties | 80 | 42 | 0 | 0 | 0 | |
| State income taxes paid | 78,000 | 0 | 0 | — | — | |
| Amounts accrued for property and equipment | 0 | 7,000 | 8,000 | 154,000 | 31,000 | |
| Amounts accrued for repurchase of common stock | 382,000 | 0 | 456,000 | 0 | 0 | |
| Receivable related to issuance of common stock, upon exercise of stock options | 29,000 | 0 | −51,000 | 40,000 | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is ANAPTYSBIO, INC's CIK number?
ANAPTYSBIO, INC's SEC CIK number is 0001370053 (1370053). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find ANAPTYSBIO, INC's SEC filings?
All of ANAPTYSBIO, INC's EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did ANAPTYSBIO, INC last report earnings?
ANAPTYSBIO, INC (ANAB) most recently filed an earnings 8-K with the SEC on May 12, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-219500). This is ANAPTYSBIO, INC's most recent earnings filing of record — not a forecast of its next earnings date.
What is ANAPTYSBIO, INC's most recent earnings 8-K?
ANAPTYSBIO, INC's latest earnings 8-K (Item 2.02) was filed May 12, 2026 under accession 0001193125-26-219500. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View ANAPTYSBIO, INC's latest earnings 8-K →
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