Eledon Pharmaceuticals, Inc.
Business
Eledon Pharmaceuticals, Inc. is a clinical-stage biotechnology company developing immunomodulatory therapies that target the CD40 Ligand (CD40L) pathway, with a primary focus on tegoprubart to protect transplanted organs and treat ALS. Its main product is tegoprubart, an engineered anti-CD40L IgG1 antibody under clinical development for kidney allograft prevention, xenotransplantation, islet cell transplantation, and ALS (IgAN deprioritized). The company operates research and development, clinical programs, intellectual property management, and third-party manufacturing partnerships. Eledon conducts clinical trials and seeks regulatory approvals across the United States, Canada, the United Kingdom, Australia and other international markets through investigator-initiated studies and collaborative arrangements.
Summary from filing dated 2025-03-20
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 66 | 52 | 30 | 27 | 24 | |
| General and administrative | 17 | 19 | 13 | 13 | 13 | |
| Total operating expenses | 83 | 71 | 43 | 88 | 37 | |
| Other income, net | 4 | 4 | 3 | 462,000 | 7,000 | |
| Change in fair value of warrant liabilities | 33 | 31 | — | — | — | |
| Loss before income taxes | −46 | −36 | −117 | −88 | −37 | |
| Provision for income taxes | −35,000 | −431,000 | 0 | 0 | 2 | |
| Net loss | −46 | −36 | −117 | −88 | −35 | |
| Unrealized loss on available-for-sale securities, net | −2,000 | — | — | — | — | |
| Comprehensive loss | −46 | −36 | — | — | — | |
| Basic earnings per share of common stock | −0.52 | −0.66 | −4.73 | −6.16 | −2.33 | |
| Diluted earnings per share of common stock | −0.52 | −0.66 | −4.73 | −6.16 | −2.33 | |
| Weighted-average common shares outstanding, basic | 82 | 49 | 25 | 14 | 15 | |
| Weighted-average common shares outstanding, diluted | 82 | 49 | 25 | 14 | 15 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 23 | 21 | 5 | 56 | 85 | |
| Short-term investments | 111 | 120 | 46 | 0 | — | |
| Prepaid expenses and other current assets | 2 | 4 | 5 | 3 | 4 | |
| Total current assets | 136 | 144 | 56 | 60 | 88 | |
| Operating lease right-of-use asset, net | 613,000 | 926,000 | 365,000 | 739,000 | 768,000 | |
| In-process research and development | 32 | 32 | 32 | 32 | 32 | |
| Other assets | 322,000 | 363,000 | 186,000 | 150,000 | 400,000 | |
| Total assets | 169 | 177 | 89 | 93 | 171 | |
| Accounts payable | 4 | 6 | 967,000 | 2 | 2 | |
| Current operating lease liability | 358,000 | 314,000 | 383,000 | 363,000 | 369,000 | |
| Accrued expenses and other liabilities | 14 | 5 | 3 | 4 | 2 | |
| Total current liabilities | 18 | 12 | 4 | 6 | 4 | |
| Deferred tax liability | 2 | 2 | 2 | 2 | 2 | |
| Non-current operating lease liability | 283,000 | 640,000 | 0 | 383,000 | 400,000 | |
| Warrant liabilities | 11 | 45 | 76 | — | — | |
| Total liabilities | 32 | 59 | 82 | 9 | 7 | |
| Commitments and contingencies (Note 7) | — | — | — | — | — | |
| Common stock, $0.001 par value, 300,000,000 and 200,000,000 shares authorized at December 31, 2025 and 2024, respectively; 75,430,033 and 59,789,275 shares issued and outstanding at December 31, 2025 and 2024, respectively | 75,000 | 60,000 | 24,000 | 14,000 | 14,000 | |
| Additional paid-in capital | 482 | 418 | 327 | 287 | 279 | |
| Accumulated other comprehensive income | 24,000 | 26,000 | — | — | — | |
| Accumulated deficit | −401 | −356 | −319 | −203 | −115 | |
| Total stockholders' equity | 81 | 62 | −48 | 84 | 164 | |
| Total liabilities, convertible preferred stock and stockholders' equity | 169 | 177 | 89 | 93 | 171 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Gain on lease termination | — | −10,000 | — | — | — | |
| Non-cash lease expense | 313,000 | 359,000 | — | — | — | |
| Accretion of investment discounts | −2 | −3 | −1 | — | — | |
| Stock-based compensation | 10 | 13 | 7 | 8 | 8 | |
| Deferred tax provision | 5,000 | 431,000 | — | — | — | |
| Prepaid expenses and other assets | 1 | 1 | −2 | 654,000 | −2 | |
| Accounts payable, accrued expenses and other liabilities | 7 | 8 | −3 | 2 | — | |
| Operating lease liabilities | −313,000 | −339,000 | −363,000 | −367,000 | −200,000 | |
| Net cash used in operating activities | −62 | −47 | −40 | −28 | −29 | |
| Purchase of available-for-sale short-term investments | −161 | −156 | −78 | — | — | |
| Proceeds from maturities of available-for-sale short-term investments | 172 | 86 | 33 | — | — | |
| Net cash provided by (used in) investing activities | 11 | −70 | −45 | — | — | |
| Proceeds from issuances of common stock and pre-funded warrants, net | 54 | 133 | 33 | — | — | |
| Proceeds from exercise of stock options | 230,000 | 215,000 | — | — | 1,000 | |
| Net cash provided by financing activities | 54 | 134 | 33 | — | −449,000 | |
| Net change in cash and cash equivalents | 2 | 16 | −52 | −28 | −29 | |
| Unrealized gain (loss) on available-for-sale securities | −2,000 | 26,000 | — | — | — | |
| Common stock exchange for warrants | 4,000 | — | — | — | 1,000 | |
| Offering costs accrued but not yet paid | 4,000 | — | — | — | — | |
| Increase in operating right-of-use lease asset and liability due to new lease | — | 920,000 | — | — | — | |
| Settlement of warrant liability into common stock due to exercise | — | 446,000 | — | — | — |