ZEVRA THERAPEUTICS, INC.
Business
Zevra Therapeutics, Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing therapeutics for rare diseases. It offers approved medicines (MIPLYFFA, OLPRUVA and AZSTARYS through a partnership) and a portfolio of clinical and preclinical product candidates including celiprolol and KP1077, together with related development, licensing and intellectual property management. Key business segments include commercial operations, clinical development, in‑licensing and acquisitions, and partnered products supported by regulatory, medical affairs and market access functions. The company markets in the U.S., pursues EU approvals and distributes via specialty pharmacies, third‑party distributors, contract manufacturers and strategic partners.
Summary from filing dated 2025-03-12
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue, net | 107 | 24 | 27 | 10 | 29 | |
| Cost of product revenue (excluding $X and $X in intangible asset amortization for the years ended XXX XX, 20XX, and 20XX, respectively, shown separately below) | 16 | 7 | 2 | — | — | |
| Intangible asset amortization | 4 | 6 | 800,000 | — | — | |
| Impairment of intangible assets | 59 | 0 | — | — | — | |
| Research and development | 13 | 42 | 40 | 20 | 10 | |
| Selling, general and administrative | 78 | 55 | 34 | 15 | — | |
| Total operating expenses | 90 | 97 | 74 | 53 | 21 | |
| Loss from operations | −63 | −87 | −50 | −43 | 8 | |
| Gain on sale of PRV | 148 | 0 | — | — | — | |
| Interest expense | −8 | −7 | −2 | — | — | |
| Fair value adjustment related to warrant and CVR liability | 2 | 2 | — | — | — | |
| Fair value adjustment related to investments | 149,000 | −18,000 | 613,000 | −577,000 | — | |
| Interest and other income, net | 7 | 2 | 5 | 2 | 261,000 | |
| Total other income (expense) | 150 | −3 | 4 | 16 | −16 | |
| Income (loss) before income taxes | 87 | −90 | −46 | −27 | −9 | |
| Income tax expense | −3 | −15 | 0 | 33,000 | −34,000 | |
| Net income (loss) | 83 | −106 | −46 | −27 | −9 | |
| Basic (in dollars per share) | 1.4 | −2.28 | −1.3 | −0.78 | −2.11 | |
| Diluted (in dollars per share) | 1.35 | −2.28 | — | — | −2.11 | |
| Basic (in shares) | 55 | 46 | 35 | 34 | 30 | |
| Diluted (in shares) | 57 | 46 | — | — | 30 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2023 2023-09-30 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 62 | 34 | 43 | — | 65 | |
| Securities at fair value, current | 129 | 36 | 25 | — | 17 | |
| Accounts and other receivables | 23 | 11 | 17 | — | 8 | |
| Prepaid expenses and other current assets | 7 | 4 | 2 | — | 2 | |
| Inventories, current | 2 | 2 | 0 | — | — | |
| Total current assets | 223 | 86 | 87 | — | 93 | |
| Securities at fair value, noncurrent | 48 | 6 | 0 | — | 0 | |
| Inventories, noncurrent | 879,000 | 11 | 10 | — | 671,000 | |
| Property and equipment, net | 489,000 | 356,000 | 736,000 | — | 794,000 | |
| Operating lease right-of-use assets | 1 | 657,000 | 790,000 | — | 988,000 | |
| Goodwill | 5 | 5 | 5 | — | 0 | |
| Intangible assets, net | 6 | 69 | 69 | — | 0 | |
| Other long-term assets | 143,000 | 384,000 | 94,000 | — | 53,000 | |
| Total assets | 285 | 178 | 172 | — | 115 | |
| Accounts payable and accrued expenses | 12 | 25 | 28 | — | 6 | |
| Current portion of operating lease liabilities | 419,000 | 420,000 | 543,000 | — | 480,000 | |
| Current portion of discount and rebate liabilities | 12 | 6 | — | — | — | |
| Current portion of income tax payable | 14 | 0 | — | — | — | |
| Other current liabilities | 1 | 2 | 3 | — | 719,000 | |
| Total current liabilities | 39 | 34 | 74 | — | 12 | |
| Long-term debt | 62 | 60 | 5 | — | — | |
| Warrant liability | 10 | 18 | — | — | — | |
| Income tax payable | 7 | 14 | 0 | — | — | |
| Operating lease liabilities, less current portion | 859,000 | 372,000 | 456,000 | — | 843,000 | |
| Discount and rebate liabilities, less current portion | 10 | 8 | — | — | — | |
| Other long-term liabilities | 2 | 5 | 7 | — | 25,000 | |
| Total liabilities | 130 | 138 | 110 | — | 40 | |
| Commitments and contingencies (Note K) | — | — | — | — | — | |
| Undesignated preferred stock, $X.X par value, X shares authorized, X shares issued or outstanding as of XXX XX, 20XX, or December 31, 20XX | 0 | 0 | — | — | 0 | |
| Common stock, $X.X par value, X shares authorized; X shares issued and X shares outstanding as of XXXX XX, 20XX; X shares issued and X shares outstanding as of December 31, 20XX | 6,000 | 5,000 | — | — | — | |
| Additional paid-in capital | 588 | 555 | 473 | — | 436 | |
| Treasury stock, at cost | −11 | −11 | −11 | — | −8 | |
| Accumulated deficit | −422 | −505 | −400 | — | −354 | |
| Accumulated other comprehensive (loss) income | −764,000 | 631,000 | −43,000 | — | 113,000 | |
| Total stockholders' equity | 155 | 40 | 62 | 62 | 75 | |
| Total liabilities and stockholders' equity | 285 | 178 | 172 | — | 115 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 13 | 15 | 6 | 4 | 2 | |
| Inventory obsolescence charge | 12 | 6 | 0 | — | — | |
| Income tax expense | 3 | 15 | 0 | — | — | |
| Depreciation and amortization expense | 4 | 6 | 1 | 944,000 | 257,000 | |
| Non-cash interest expense | 3 | 2 | 0 | 0 | 8,000 | |
| Non-cash lease expense | 602,000 | 552,000 | — | — | — | |
| Accretion on investments | −3 | −890,000 | 0 | — | — | |
| Loss on sublease and disposal of property and equipment | 63,000 | 218,000 | 157,000 | 9,000 | 76,000 | |
| Consulting fees paid in common stock | 75,000 | 474,000 | — | — | — | |
| Loss on foreign currency exchange rates | 2 | 219,000 | −198,000 | −91,000 | 0 | |
| Accounts and other receivables | −12 | 7 | −9 | −7 | 1 | |
| Prepaid expenses and other current assets | −3 | −2 | 152,000 | −894,000 | −825,000 | |
| Inventories | −1 | −9 | 206,000 | 147,000 | 0 | |
| Other long-term assets | 451,000 | 0 | −5,000 | 386,000 | 0 | |
| Accounts payable and accrued expenses | −16 | −4 | 11 | 3 | −1 | |
| Discount and rebate liabilities | 7 | 431,000 | 3 | 4 | 0 | |
| Operating lease liabilities | −675,000 | −626,000 | −439,000 | −389,000 | −326,000 | |
| Other liabilities | −1 | 835,000 | 360,000 | −74,000 | 723,000 | |
| Net cash used in operating activities | −2 | −70 | −34 | −19 | 10 | |
| Purchases of property and equipment | −835,000 | 0 | −296,000 | −93,000 | −102,000 | |
| Disposals of property and equipment | 448,000 | 0 | — | — | — | |
| Purchases of investments | −310 | −41 | −46 | — | — | |
| Maturities of investments | 179 | 25 | 59 | 1 | — | |
| Proceeds from sale of PRV | 150 | 0 | — | — | — | |
| Payment of royalty to XOMA | 0 | −6 | 0 | — | — | |
| Net cash provided by (used in) investing activities | 18 | −22 | −17 | −37 | −16 | |
| Proceeds from issuance of debt, net of lender fees | 0 | 59 | 42 | 13 | 0 | |
| Repayment of debt | 0 | −43 | −18 | 0 | — | |
| Proceeds from insurance financing arrangements | 0 | 1 | 1 | 1 | 0 | |
| Proceeds from Employee Stock Purchase Plan | 615,000 | 1 | — | — | — | |
| Proceeds from issuance of stock | 0 | 65 | 6 | 0 | — | |
| Proceeds from issuance of common stock for options exercised | 3 | 2 | 0 | — | — | |
| Proceeds from issuance of common stock for warrants exercised | 9 | 0 | — | 0 | 31 | |
| Payments of principal on insurance financing arrangements | −372,000 | −431,000 | −564,000 | −1 | 0 | |
| Payment of deferred financing costs | 0 | −2 | 0 | — | — | |
| Net cash provided by financing activities | 12 | 82 | 28 | 8 | 113 | |
| Effect of exchange rate changes on cash and cash equivalents | 28,000 | 454,000 | 44,000 | 204,000 | 0 | |
| Net increase (decrease) in cash and cash equivalents | 29 | −9 | −22 | −47 | 108 | |
| Cash paid for interest | 5 | 5 | 456,000 | 321,000 | 218,000 | |
| Right-of-use assets obtained in exchange for lease liabilities | 1 | 419,000 | 0 | — | — |