Adaptive Biotechnologies Corp
Business
Adaptive Biotechnologies Corp harnesses the adaptive immune system to read immune receptor genetics and translate those insights into diagnostic and therapeutic products and services. Its offerings include an immunosequencing platform and related tools (clonoSEQ, MIRA, pairSEQ and antibody discovery) for detection, antigen mapping and therapeutic candidate characterization, plus clinical diagnostic testing and assay services for biopharmaceutical partners. The company operates two businesses: an MRD business (clonoSEQ clinical diagnostic testing and MRD Pharma services) and an Immune Medicine business (drug discovery and IM Pharma partnerships). It distributes tests and services through U.S. clinical channels with payor coverage and EMR integrations, supports biopharmaceutical clinical trials worldwide, and licenses technology to international partner laboratories.
Summary from filing dated 2025-03-03
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Revenue | 277 | 179 | 170 | 185 | 154 | |
| Cost of revenue | 71 | 72 | 76 | 58 | 49 | |
| Research and development | 94 | 103 | 122 | 142 | 142 | |
| Sales and marketing | 95 | 85 | 89 | 96 | 95 | |
| General and administrative | 73 | 73 | 84 | 89 | 75 | |
| Amortization of intangible assets | 2 | 2 | 2 | 2 | 2 | |
| Impairment of long-lived assets | 0 | 7 | 25 | — | — | |
| Total operating expenses | 334 | 342 | 397 | 385 | 363 | |
| Loss from operations | −57 | −163 | −227 | −200 | −209 | |
| Interest and other income, net | 9 | 15 | 16 | 4 | 2 | |
| Interest expense | −12 | −12 | −14 | −4 | — | |
| Net loss | −59 | −160 | −225 | −200 | −207 | |
| Add: Net (income) loss attributable to noncontrolling interest | −42,000 | 103,000 | 54,000 | 177,000 | 19,000 | |
| Net loss attributable to Adaptive Biotechnologies Corporation | −59 | −159 | −225 | −200 | −207 | |
| Net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic | −0.39 | −1.08 | −1.56 | −1.4 | −1.48 | |
| Net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, diluted | −0.39 | −1.08 | −1.56 | −1.4 | −1.48 | |
| Weighted-average shares used in computing net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic | 152 | 147 | 144 | 143 | 140 | |
| Weighted-average shares used in computing net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, diluted | 152 | 147 | 144 | 143 | 140 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 70 | 48 | 65 | 90 | 139 | |
| Short-term marketable securities (amortized cost of $156,246 and $174,186, respectively) | 156 | 174 | 281 | 408 | 214 | |
| Accounts receivable, net | 50 | 42 | 38 | 40 | 17 | |
| Inventory | 10 | 8 | 14 | 14 | 19 | |
| Prepaid expenses and other current assets | 13 | 11 | 11 | 9 | 13 | |
| Total current assets | 300 | 284 | 410 | 562 | 403 | |
| Property and equipment, net | 34 | 49 | 68 | 83 | 85 | |
| Operating lease right-of-use assets | 41 | 46 | 52 | 81 | 88 | |
| Long-term marketable securities (amortized cost of $13,220 and $33,682, respectively) | 13 | 34 | — | — | 217 | |
| Restricted cash | 3 | 3 | 3 | 2 | 2 | |
| Intangible assets, net | 2 | 3 | 5 | 7 | 9 | |
| Goodwill | 119 | 119 | 119 | 119 | 119 | |
| Other assets | 1 | 2 | 4 | 2 | 875,000 | |
| Total assets | 513 | 539 | 661 | 857 | 923 | |
| Accounts payable | 6 | 7 | 8 | 8 | 3 | |
| Accrued liabilities | 8 | 8 | 9 | 12 | 9 | |
| Accrued compensation and benefits | 17 | 16 | 14 | 16 | 16 | |
| Current portion of operating lease liabilities | 9 | 10 | 9 | 9 | 5 | |
| Current portion of deferred revenue | 45 | 56 | 49 | 64 | 80 | |
| Current portion of revenue interest liability, net | 5 | 865,000 | — | — | — | |
| Total current liabilities | 90 | 98 | 88 | 110 | 114 | |
| Operating lease liabilities, less current portion | 70 | 79 | 89 | 99 | 107 | |
| Deferred revenue, less current portion | 1 | 27 | 45 | 59 | 99 | |
| Revenue interest liability, net, less current portion | 127 | 132 | 131 | 125 | — | |
| Other long-term liabilities | 20,000 | 20,000 | — | — | — | |
| Total liabilities | 288 | 337 | 353 | 393 | 319 | |
| Commitments and contingencies (Note 12) | — | — | — | — | — | |
| Preferred stock: $0.0001 par value, 10,000,000 shares authorized at December 31, 2025 and 2024; no shares issued and outstanding at December 31, 2025 and 2024 | — | — | — | — | — | |
| Common stock: $0.0001 par value, 340,000,000 shares authorized at December 31, 2025 and 2024; 153,779,418 and 147,773,744 shares issued and outstanding at December 31, 2025 and 2024, respectively | 15,000 | 14,000 | 14,000 | 14,000 | 14,000 | |
| Additional paid-in capital | 1,582 | 1,506 | 1,453 | 1,387 | 1,324 | |
| Accumulated other comprehensive gain | 253,000 | 166,000 | 215,000 | −4 | −1 | |
| Accumulated deficit | −1,363 | −1,304 | −1,144 | −919 | −719 | |
| Total Adaptive Biotechnologies Corporation shareholders equity | 219 | 203 | 308 | 464 | 604 | |
| Noncontrolling interest | 6 | −224,000 | −121,000 | −67,000 | 110,000 | |
| Total shareholders equity | 225 | 202 | 308 | 464 | 604 | |
| Total liabilities and shareholders equity | 513 | 539 | 661 | 857 | 923 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation expense | 16 | 18 | 21 | 19 | 12 | |
| Noncash lease expense | 5 | 5 | 7 | 7 | 7 | |
| Share-based compensation expense | 51 | 54 | 63 | 55 | 43 | |
| Investment amortization | −3 | −8 | −9 | 741,000 | 7 | |
| Impairment of long-lived assets | 0 | 7 | 25 | — | — | |
| Write-off of inventory | 563,000 | 2 | 1 | — | — | |
| Revenue interest purchase agreement interest | −2 | 3 | 5 | — | — | |
| Other | 578,000 | 141,000 | 172,000 | −19,000 | −78,000 | |
| Accounts receivable, net | −9 | −4 | 2 | −23 | −7 | |
| Inventory | −998,000 | 5 | −3 | 817,000 | −5 | |
| Prepaid expenses and other current assets | −2 | 83,000 | −2 | 4 | 1 | |
| Accounts payable and accrued liabilities | 665,000 | 671,000 | −5 | 7 | 4 | |
| Operating lease right-of-use assets and liabilities | −10 | −9 | −9 | −4 | 9 | |
| Deferred revenue | −37 | −10 | −29 | −56 | −58 | |
| Other | 142,000 | 27,000 | −73,000 | 169,000 | −275,000 | |
| Net cash used in operating activities | −46 | −95 | −156 | −184 | −193 | |
| Purchases of property and equipment | −3 | −4 | −11 | −16 | −62 | |
| Purchases of marketable securities | −182 | −244 | −430 | −279 | −317 | |
| Proceeds from maturities of marketable securities | 223 | 326 | 570 | 298 | 560 | |
| Net cash provided by investing activities | 38 | 78 | 130 | 3 | 181 | |
| Proceeds from exercise of stock options | 18 | 241,000 | 2 | 8 | 27 | |
| Proceeds from capital contributions for Digital Biotechnologies, Inc. | 13 | 0 | 0 | — | 429,000 | |
| Cash provided by financing activities | 30 | 241,000 | 2 | 132 | 27 | |
| Net increase (decrease) in cash, cash equivalents and restricted cash | 22 | −17 | −24 | −49 | 16 | |
| Purchases of equipment included in accounts payable and accrued liabilities | 509,000 | 1 | 687,000 | 2 | 682,000 | |
| Cash paid for interest | 13 | 9 | 9 | 494,000 | — |