Akebia Therapeutics, Inc.
Business
Akebia Therapeutics, Inc. is a fully integrated biopharmaceutical company focused on developing, commercializing and supplying therapies for complications of kidney disease. It commercializes two oral products—Vafseo (vadadustat), an oral HIF prolyl hydroxylase inhibitor for anemia in dialysis patients, and Auryxia (ferric citrate) for hyperphosphatemia and iron deficiency anemia—while advancing HIF‑based candidates and other pipeline assets. Its operations include commercial sales, research and development, preclinical programs and licensing/collaboration arrangements. Akebia distributes products and collaborates with partners across the U.S., Europe, UK, Switzerland, Australia, Japan, Taiwan, Korea and through dialysis organizations, wholesalers and specialty pharmacies.
Summary from filing dated 2025-03-13
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 236 | 160 | 195 | 292 | 214 | |
| Cost of product and other revenue | 39 | 27 | 38 | 50 | 117 | |
| Amortization of intangible asset | 0 | 36 | 36 | 36 | 36 | |
| Total cost of goods sold | 39 | 63 | 74 | 86 | 153 | |
| Research and development | 62 | 38 | 63 | 130 | 148 | |
| Selling, general and administrative | 107 | 107 | 100 | 139 | 174 | |
| License | 3 | 3 | 3 | 3 | 3 | |
| Restructuring | 0 | 58,000 | 181,000 | 16 | 0 | |
| Total operating expenses | 173 | 147 | 167 | 288 | 326 | |
| Income (loss) from operations | 23 | −50 | −46 | −81 | −265 | |
| Interest expense | −24 | −18 | −6 | −16 | −20 | |
| Other income | 58,000 | 94,000 | 887,000 | 3 | 2 | |
| Change in fair value of warrant liability | −3 | −330,000 | 0 | — | — | |
| Loss on extinguishment of debt | 0 | −517,000 | 0 | −906,000 | 0 | |
| Loss on termination of lease | 0 | 0 | −500,000 | 0 | — | |
| Loss before income taxes | −4 | −69 | −52 | −94 | −283 | |
| Income tax expense | −2 | 0 | 0 | 0 | 0 | |
| Net loss | −5 | −69 | −52 | −94 | −283 | |
| Comprehensive loss | −5 | −69 | −52 | −94 | −283 | |
| Basic (in dollars per share) | −0.02 | −0.33 | −0.28 | −0.52 | −1.7 | |
| Diluted (in dollars per share) | −0.02 | −0.33 | −0.28 | −0.52 | −1.7 | |
| Basic (in shares) | 257 | 211 | 187 | 183 | 166 | |
| Diluted (in shares) | 257 | 211 | 187 | 183 | 166 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 185 | 52 | 43 | 90 | 150 | |
| Inventories | 16 | 16 | 16 | 22 | 38 | |
| Accounts receivable, net | 47 | 34 | 39 | 40 | 51 | |
| Prepaid expenses and other current assets | 5 | 11 | 20 | 33 | 33 | |
| Total current assets | 253 | 114 | 118 | 185 | 272 | |
| Property and equipment, net | 1 | 2 | 4 | 5 | 7 | |
| Operating right-of-use assets | 4 | 8 | 12 | 29 | 34 | |
| Goodwill | 59 | 59 | 59 | 59 | 55 | |
| Other long-term assets | 60 | 37 | 12 | 5 | 50 | |
| Total assets | 377 | 221 | 242 | 356 | 526 | |
| Accounts payable | 21 | 15 | 15 | 18 | 34 | |
| Accrued expenses and other current liabilities | 122 | 63 | 68 | 76 | 104 | |
| Short-term deferred revenue | 3 | 0 | 0 | 4 | 21 | |
| Working Capital Fund liability, current portion | 17 | 2 | 0 | — | — | |
| Total current liabilities | 163 | 81 | 100 | 130 | 256 | |
| Long-term operating lease liabilities | 0 | 4 | 9 | 29 | 34 | |
| Long-term debt, net | 48 | 39 | 17 | 34 | 0 | |
| Liability related to settlement royalties, net of current portion | 55 | 47 | 0 | — | — | |
| Liability related to sale of future royalties, net of current portion | 51 | 52 | 54 | 57 | 53 | |
| Working Capital Fund liability, net of current portion | 23 | 38 | 40 | 41 | — | |
| Warrant liability | 3 | 5 | 0 | — | — | |
| Other long-term liabilities | 2 | 5 | 9 | 16 | 83 | |
| Total liabilities | 344 | 270 | 272 | 351 | 449 | |
| Commitments and contingencies (Note 10) | — | — | — | — | — | |
| Preferred stock $0.00001 par value, 25,000,000 shares authorized; no shares issued and outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock: $0.00001 par value; 350,000,000 shares authorized at December 31, 2025 and 2024; 265,424,818 and 224,848,992 shares issued and outstanding at December 31, 2025 and 2024, respectively | 2,000 | 2,000 | 2,000 | 2,000 | 1,000 | |
| Additional paid-in capital | 1,716 | 1,629 | 1,578 | 1,562 | 1,537 | |
| Accumulated other comprehensive income | 6,000 | 6,000 | 6,000 | 6,000 | 6,000 | |
| Accumulated deficit | −1,684 | −1,678 | −1,609 | −1,557 | −1,460 | |
| Total stockholders' equity (deficit) | 33 | −49 | −31 | 5 | 74 | |
| Total liabilities and stockholders' equity (deficit) | 377 | 221 | 242 | 356 | 526 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation | 1 | 1 | 2 | 2 | — | |
| Amortization of intangible asset | 0 | 36 | 36 | 36 | 36 | |
| Bad debt expense | 1 | 876,000 | 0 | — | — | |
| Non-cash royalty revenue related to sale of future royalties | −2 | −2 | −2 | −2 | −821,000 | |
| Non-cash research and development expense | 0 | 0 | 782,000 | 9 | 0 | |
| Non-cash interest expense | 22 | 13 | −2 | 2 | 1 | |
| Non-cash operating lease expense | 5 | 4 | 4 | −2 | −2 | |
| Non-cash loss on extinguishment of debt | 0 | 294,000 | 0 | 406,000 | — | |
| Non-cash write-off on termination of lease | 0 | 0 | −825,000 | 0 | — | |
| Charge for purchase of IPR&D asset | 13 | 0 | 0 | — | — | |
| Write-down of inventory | 3 | 4 | 2 | 30 | 16 | |
| Change in excess inventory purchase commitments | 0 | 2 | 2 | −68 | 33 | |
| Stock-based compensation expense | 11 | 8 | 9 | 18 | 23 | |
| Gain on the sale of property and equipment | −172,000 | 0 | 0 | — | — | |
| Change in fair value of embedded debt derivative | 0 | 0 | −760,000 | −1 | −600,000 | |
| Accounts receivable | −14 | 4 | 994,000 | 11 | −24 | |
| Inventory | −23 | −28 | −3 | 19 | −26 | |
| Prepaid expenses and other current assets | 8 | 9 | 12 | 1 | −19 | |
| Other long-term assets | −3 | 622,000 | −1 | −6 | 6 | |
| Accounts payable | 3 | −1 | −5 | 2 | −12 | |
| Accrued expense and other current liabilities | 49 | −13 | −10 | −38 | −25 | |
| Operating lease liabilities | −5 | −4 | −5 | 2 | — | |
| Deferred revenue | 3 | 0 | −4 | 5 | 2 | |
| Other long-term liabilities | −112,000 | −6 | −6 | 2 | −12 | |
| Net cash provided by (used in) operating activities | 68 | −41 | −23 | −73 | −253 | |
| Purchase of equipment | −291,000 | −33,000 | 0 | −114,000 | −59,000 | |
| Proceeds from the sale of property and equipment | 172,000 | 0 | 0 | — | — | |
| Purchase of IPR&D asset, including transaction costs | −8 | 0 | 0 | — | — | |
| Net cash used in investing activities | −8 | −33,000 | 0 | −114,000 | 40 | |
| Proceeds from the issuance of debt | 10 | 45 | 0 | — | — | |
| Payments of issuance costs related to BlackRock Credit Agreement | −63,000 | −1 | 0 | — | — | |
| Proceeds from the issuance of common stock, net of issuance costs | 66 | 42 | 7 | 7 | 88 | |
| Proceeds from the sale of stock under employee stock purchase plan | 230,000 | 154,000 | 85,000 | 410,000 | 746,000 | |
| Proceeds from the exercise of common stock options | 2 | 385,000 | 1,000 | 67,000 | 0 | |
| Repayment of WCF liability | −1 | 0 | 0 | — | — | |
| Repayment of liability related to settlement royalties | −4 | 0 | 0 | — | — | |
| Repayment of term debt | −462,000 | −37 | −32 | — | — | |
| Net cash provided by (used in) financing activities | 73 | 50 | −25 | 15 | 134 | |
| Increase (decrease) in cash, cash equivalents and restricted cash | 133 | 9 | −49 | −59 | −79 | |
| Issuance of warrants in connection with BlackRock Credit Agreement | 2 | 5 | 0 | — | — | |
| Cashless exercise of warrants in connection with BlackRock Credit Agreement | 7 | 0 | 0 | — | — | |
| Purchase of IPR&D asset included in accrued expenses and other current liabilities | 5 | 0 | 0 | — | — | |
| Cash paid for interest | 6 | 5 | 6 | 7 | 10 |