Verastem, Inc.
Business
Verastem, Inc. is a late-stage development biopharmaceutical company focused on developing and commercializing small molecule medicines for RAS/MAPK pathway-driven cancers. Its main product candidates include avutometinib (a RAF/MEK clamp), defactinib (a FAK/PYK2 inhibitor), and VS-7375 (a KRAS G12D inhibitor), pursued as monotherapy and in combination regimens. Key business segments comprise its RAF/MEK inhibition, FAK inhibition and KRAS inhibition programs, clinical development programs (including RAMP and FRAME trials), and collaboration/licensing activities. Clinical and commercial activities operate through global clinical trials, strategic partnerships, third-party contract manufacturers, and regulatory submissions in the United States, Europe, Japan and other regions.
Summary from filing dated 2025-03-20
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 31 | 10 | — | 3 | 2 | |
| Cost of sales - product | 5 | — | — | — | — | |
| Cost of sales - intangible amortization | 700,000 | — | — | — | — | |
| Research and development | 115 | 81 | 61 | 51 | 39 | |
| Selling, general and administrative | 81 | 44 | 31 | 25 | 24 | |
| Total operating expenses | 201 | 125 | 92 | 76 | 63 | |
| Loss from operations | −170 | −115 | −92 | −73 | −61 | |
| Other expense | −203,000 | −123,000 | −109,000 | 47,000 | — | |
| Interest income | 4 | 4 | 6 | 1 | 181,000 | |
| Interest expense | −1 | −5 | −4 | −2 | −10 | |
| Loss on debt extinguishment | −2 | — | — | — | — | |
| Change in fair value of preferred stock tranche liability | — | 4 | 3 | — | — | |
| Change in fair value of warrant liability | −27 | −19 | — | — | — | |
| Change in fair value of Notes | −13 | — | — | — | — | |
| Net loss before taxes | −209 | −130 | −87 | −74 | −71 | |
| Income tax expense | — | −200,000 | — | 0 | 0 | |
| Net loss | −209 | −131 | −87 | −74 | −71 | |
| Net loss per share-basic | −3.02 | −3.66 | −3.96 | −4.57 | −4.9 | |
| Net loss per share-diluted | −3.02 | −3.66 | −3.96 | −4.57 | −4.9 | |
| Weighted average common shares outstanding used in computing net loss per share - basic | 69 | 36 | 22 | 16 | 15 | |
| Weighted average common shares outstanding used in computing net loss per share - diluted | 69 | 36 | 22 | 16 | 15 | |
| Unrealized gain (loss) on available-for-sale securities | — | −13,000 | 13,000 | −34,000 | −19,000 | |
| Change in fair value of Notes attributable to instrument specific credit risk | 5 | — | — | — | — | |
| Comprehensive loss | −204 | −131 | −87 | −74 | −71 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2024 2024-11-30 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 205 | 89 | — | 78 | 75 | |
| Accounts receivable, net | 9 | — | — | — | 31,000 | |
| Inventory | 2 | — | — | — | — | |
| Grant receivable | 200,000 | 200,000 | — | — | — | |
| Prepaid expenses and other current assets | 8 | 6 | — | 7 | 5 | |
| Total current assets | 223 | 95 | — | 144 | 93 | |
| Property and equipment, net | — | 32,000 | — | 37,000 | 92,000 | |
| Right-of-use asset, net | 500,000 | 1 | 1 | 1 | 2 | |
| Restricted cash | — | 241,000 | — | 241,000 | 241,000 | |
| Intangible assets, net | 16 | — | — | — | — | |
| Other assets | 6 | 5 | — | 5 | 58,000 | |
| Total assets | 246 | 102 | — | 150 | 95 | |
| Accounts payable | 12 | 4 | — | 7 | 5 | |
| Accrued expenses, short-term | 54 | 26 | — | 18 | 15 | |
| Vendor financing arrangement, short-term | 5 | — | — | — | — | |
| Lease liability, short-term | 535,000 | 995,000 | — | 941,000 | 794,000 | |
| Total current liabilities | 72 | 31 | — | 26 | 22 | |
| Long-term debt | 76 | 41 | — | 40 | 25 | |
| Vendor financing arrangement, long-term | 5 | — | — | — | — | |
| Lease liability, long-term | — | 535,000 | — | 530,000 | 1 | |
| Warrant liability | 36 | 58 | — | — | — | |
| Total liabilities | 189 | 130 | — | 71 | 48 | |
| Series B Convertible Preferred Stock, $0.0001 par value; 944 shares designated at December 31, 2025 and December 31, 2024, respectively; 0 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | — | — | — | 21 | — | |
| Preferred stock, $0.0001 par value; 5,000 shares authorized: Series A Convertible Preferred Stock, $0.0001 par value; 0 shares and 1,000 shares designated at December 31, 2025 and December 31, 2024, respectively, 0 shares and 1,000 shares issued and outstanding at December 31, 2025 and at December 31, 2024, respectively | — | — | — | — | — | |
| Common stock, $0.0001 par value; 300,000 shares authorized, 77,740 and 44,784 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 8,000 | 4,000 | — | 3,000 | 2,000 | |
| Additional paid-in capital | 1,217 | 927 | — | 882 | 785 | |
| Accumulated other comprehensive income | 5 | — | — | 13,000 | — | |
| Accumulated deficit | −1,165 | −956 | — | −825 | −738 | |
| Total stockholders' equity (deficit) | 57 | −29 | — | 57 | 47 | |
| Total liabilities, convertible preferred stock and stockholders' equity | 246 | 102 | — | 150 | 95 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −209 | −131 | −87 | −74 | −71 | |
| Depreciation | 30,000 | 26,000 | 62,000 | 100,000 | 200,000 | |
| Amortization of acquired intangible assets | 698,000 | — | — | — | — | |
| Non-cash operating lease cost | −81,000 | −175,000 | −175,000 | −154,000 | — | |
| Stock-based compensation expense | 9 | 7 | 6 | 6 | 8 | |
| Amortization of deferred financing costs, debt discounts and premiums and discounts on available-for-sale marketable securities | 29,000 | −5,000 | −1 | 228,000 | 9 | |
| Change in fair value of preferred stock tranche liability | — | −4 | −3 | — | — | |
| Non-cash change in fair value of Notes | 7 | — | — | — | — | |
| Accounts receivable, net | −9 | — | 31,000 | 485,000 | −277,000 | |
| Grant receivable | — | −200,000 | — | — | — | |
| Inventory | −2 | — | — | — | — | |
| Prepaid expenses, other current assets and other assets | −3 | −596,000 | −6 | 744,000 | −2 | |
| Accounts payable | 8 | −3 | 2 | 3 | 623,000 | |
| Accrued expenses and other liabilities | 31 | 8 | 3 | −638,000 | 2 | |
| Deferred liabilities | — | −327,000 | −383,000 | 710,000 | — | |
| Net cash used in operating activities | −138 | −105 | −86 | −64 | −54 | |
| Purchases of property and equipment | — | −28,000 | — | — | −196,000 | |
| Purchases of intangible assets | −10 | — | — | — | — | |
| Purchases of investments | — | — | −96 | −18 | −86 | |
| Maturities of investments | — | 60 | 52 | 84 | 87 | |
| Net cash (used in) provided by investing activities | −10 | 60 | −44 | 66 | 87,000 | |
| Proceeds from the issuance of common stock and pre-funded warrants, net | 197 | 14 | 91 | 27 | 7 | |
| Proceeds from the issuance of warrants | — | 40 | — | — | — | |
| Proceeds from issuance of Series B Convertible Preferred Stock, net | — | — | 28 | — | — | |
| Proceeds from exercise of warrants | 34 | 875,000 | — | — | — | |
| Proceeds from long-term debt | 75 | — | 15 | 24 | 1 | |
| Repayment of long-term debt | −43 | — | −300,000 | — | — | |
| Payments for loan amendment | — | −150,000 | — | — | — | |
| Repayment of 2018 Notes | — | — | −300,000 | — | — | |
| Proceeds from insurance premium financing | 1 | 1 | 1 | — | — | |
| Payments on insurance premium financing | −1 | −1 | −1 | — | — | |
| Proceeds from the exercise of stock options and employee stock purchase program | 116,000 | 241,000 | 57,000 | 282,000 | 1 | |
| Net cash provided by financing activities | 263 | 55 | 134 | 52 | 7 | |
| Increase in cash, cash equivalents and restricted cash | 116 | 10 | 3 | 54 | −47 | |
| Cash paid for interest | 6 | 4 | 3 | 2 | 1 | |
| Cash paid for income tax expense | 185,000 | — | — | — | — | |
| Purchases of property and equipment included in accounts payable and accrued expenses | — | — | 7,000 | — | — | |
| Issuance costs included in accounts payable and accrued expenses | — | 32,000 | — | — | — | |
| Conversion of warrant liability into additional paid-in capital upon warrant exercise | 50 | 545,000 | — | — | — | |
| Right of use asset obtained in exchange for operating lease liability | — | 988,000 | — | — | — | |
| Purchases of intangible asset in accounts payable and accrued expenses | 8 | — | — | — | — |