Verastem, Inc.
Business
Verastem is a biopharmaceutical company developing and commercializing novel medicines targeting RAS/MAPK pathway-driven cancers. The company markets AVMAPKI FAKZYNJA CO-PACK (avutometinib plus defactinib), the first FDA-approved treatment for KRAS-mutated recurrent low-grade serous ovarian cancer, approved in May 2025. The pipeline includes VS-7375, a potential best-in-class oral KRAS G12D inhibitor in Phase 1/2 trials, and preclinical programs targeting RAS/MAPK pathway-driven cancers. The company operates primarily in the U.S. market with ongoing geographic expansion efforts in Europe and Japan.
Summary from 10-K filed 2026-03-04
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 31 | 10 | — | 3 | 2 | |
| Cost of sales - product | 5 | — | — | — | — | |
| Cost of sales - intangible amortization | 700,000 | — | — | — | — | |
| Research and development | 115 | 81 | 61 | 51 | 39 | |
| Selling, general and administrative | 81 | 44 | 31 | 25 | 24 | |
| Total operating expenses | 201 | 125 | 92 | 76 | 63 | |
| Loss from operations | −170 | −115 | −92 | −73 | −61 | |
| Other expense | −203,000 | −123,000 | −109,000 | 47,000 | — | |
| Interest income | 4 | 4 | 6 | 1 | 181,000 | |
| Interest expense | −1 | −5 | −4 | −2 | −10 | |
| Loss on debt extinguishment | −2 | — | — | — | — | |
| Change in fair value of preferred stock tranche liability | — | 4 | 3 | — | — | |
| Change in fair value of warrant liability | −27 | −19 | — | — | — | |
| Change in fair value of Notes | −13 | — | — | — | — | |
| Net loss before taxes | −209 | −130 | −87 | −74 | −71 | |
| Income tax expense | — | −200,000 | — | 0 | 0 | |
| Net loss | −209 | −131 | −87 | −74 | −71 | |
| Net loss per share-basic | −3.02 | −3.66 | −3.96 | −4.57 | −4.9 | |
| Net loss per share-diluted | −3.02 | −3.66 | −3.96 | −4.57 | −4.9 | |
| Weighted average common shares outstanding used in computing net loss per share - basic | 69 | 36 | 22 | 16 | 15 | |
| Weighted average common shares outstanding used in computing net loss per share - diluted | 69 | 36 | 22 | 16 | 15 | |
| Unrealized gain (loss) on available-for-sale securities | — | −13,000 | 13,000 | −34,000 | −19,000 | |
| Change in fair value of Notes attributable to instrument specific credit risk | 5 | — | — | — | — | |
| Comprehensive loss | −204 | −131 | −87 | −74 | −71 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2024 2024-11-30 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 205 | 89 | — | 78 | 75 | |
| Accounts receivable, net | 9 | — | — | — | 31,000 | |
| Inventory | 2 | — | — | — | — | |
| Grant receivable | 200,000 | 200,000 | — | — | — | |
| Prepaid expenses and other current assets | 8 | 6 | — | 7 | 5 | |
| Total current assets | 223 | 95 | — | 144 | 93 | |
| Property and equipment, net | — | 32,000 | — | 37,000 | 92,000 | |
| Right-of-use asset, net | 500,000 | 1 | 1 | 1 | 2 | |
| Restricted cash | — | 241,000 | — | 241,000 | 241,000 | |
| Intangible assets, net | 16 | — | — | — | — | |
| Other assets | 6 | 5 | — | 5 | 58,000 | |
| Total assets | 246 | 102 | — | 150 | 95 | |
| Accounts payable | 12 | 4 | — | 7 | 5 | |
| Accrued expenses, short-term | 54 | 26 | — | 18 | 15 | |
| Vendor financing arrangement, short-term | 5 | — | — | — | — | |
| Lease liability, short-term | 535,000 | 995,000 | — | 941,000 | 794,000 | |
| Total current liabilities | 72 | 31 | — | 26 | 22 | |
| Long-term debt | 76 | 41 | — | 40 | 25 | |
| Vendor financing arrangement, long-term | 5 | — | — | — | — | |
| Lease liability, long-term | — | 535,000 | — | 530,000 | 1 | |
| Warrant liability | 36 | 58 | — | — | — | |
| Total liabilities | 189 | 130 | — | 71 | 48 | |
| Series B Convertible Preferred Stock, $0.0001 par value; 944 shares designated at December 31, 2025 and December 31, 2024, respectively; 0 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | — | — | — | 21 | — | |
| Preferred stock, $0.0001 par value; 5,000 shares authorized: Series A Convertible Preferred Stock, $0.0001 par value; 0 shares and 1,000 shares designated at December 31, 2025 and December 31, 2024, respectively, 0 shares and 1,000 shares issued and outstanding at December 31, 2025 and at December 31, 2024, respectively | — | — | — | — | — | |
| Common stock, $0.0001 par value; 300,000 shares authorized, 77,740 and 44,784 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 8,000 | 4,000 | — | 3,000 | 2,000 | |
| Additional paid-in capital | 1,217 | 927 | — | 882 | 785 | |
| Accumulated other comprehensive income | 5 | — | — | 13,000 | — | |
| Accumulated deficit | −1,165 | −956 | — | −825 | −738 | |
| Total stockholders' equity (deficit) | 57 | −29 | — | 57 | 47 | |
| Total liabilities, convertible preferred stock and stockholders' equity | 246 | 102 | — | 150 | 95 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −209 | −131 | −87 | −74 | −71 | |
| Depreciation | 30,000 | 26,000 | 62,000 | 100,000 | 200,000 | |
| Amortization of acquired intangible assets | 698,000 | — | — | — | — | |
| Non-cash operating lease cost | −81,000 | −175,000 | −175,000 | −154,000 | — | |
| Stock-based compensation expense | 9 | 7 | 6 | 6 | 8 | |
| Amortization of deferred financing costs, debt discounts and premiums and discounts on available-for-sale marketable securities | 29,000 | −5,000 | −1 | 228,000 | 9 | |
| Change in fair value of preferred stock tranche liability | — | −4 | −3 | — | — | |
| Non-cash change in fair value of Notes | 7 | — | — | — | — | |
| Accounts receivable, net | −9 | — | 31,000 | 485,000 | −277,000 | |
| Grant receivable | — | −200,000 | — | — | — | |
| Inventory | −2 | — | — | — | — | |
| Prepaid expenses, other current assets and other assets | −3 | −596,000 | −6 | 744,000 | −2 | |
| Accounts payable | 8 | −3 | 2 | 3 | 623,000 | |
| Accrued expenses and other liabilities | 31 | 8 | 3 | −638,000 | 2 | |
| Deferred liabilities | — | −327,000 | −383,000 | 710,000 | — | |
| Net cash used in operating activities | −138 | −105 | −86 | −64 | −54 | |
| Purchases of property and equipment | — | −28,000 | — | — | −196,000 | |
| Purchases of intangible assets | −10 | — | — | — | — | |
| Purchases of investments | — | — | −96 | −18 | −86 | |
| Maturities of investments | — | 60 | 52 | 84 | 87 | |
| Net cash (used in) provided by investing activities | −10 | 60 | −44 | 66 | 87,000 | |
| Proceeds from the issuance of common stock and pre-funded warrants, net | 197 | 14 | 91 | 27 | 7 | |
| Proceeds from the issuance of warrants | — | 40 | — | — | — | |
| Proceeds from issuance of Series B Convertible Preferred Stock, net | — | — | 28 | — | — | |
| Proceeds from exercise of warrants | 34 | 875,000 | — | — | — | |
| Proceeds from long-term debt | 75 | — | 15 | 24 | 1 | |
| Repayment of long-term debt | −43 | — | −300,000 | — | — | |
| Payments for loan amendment | — | −150,000 | — | — | — | |
| Repayment of 2018 Notes | — | — | −300,000 | — | — | |
| Proceeds from insurance premium financing | 1 | 1 | 1 | — | — | |
| Payments on insurance premium financing | −1 | −1 | −1 | — | — | |
| Proceeds from the exercise of stock options and employee stock purchase program | 116,000 | 241,000 | 57,000 | 282,000 | 1 | |
| Net cash provided by financing activities | 263 | 55 | 134 | 52 | 7 | |
| Increase in cash, cash equivalents and restricted cash | 116 | 10 | 3 | 54 | −47 | |
| Cash paid for interest | 6 | 4 | 3 | 2 | 1 | |
| Cash paid for income tax expense | 185,000 | — | — | — | — | |
| Purchases of property and equipment included in accounts payable and accrued expenses | — | — | 7,000 | — | — | |
| Issuance costs included in accounts payable and accrued expenses | — | 32,000 | — | — | — | |
| Conversion of warrant liability into additional paid-in capital upon warrant exercise | 50 | 545,000 | — | — | — | |
| Right of use asset obtained in exchange for operating lease liability | — | 988,000 | — | — | — | |
| Purchases of intangible asset in accounts payable and accrued expenses | 8 | — | — | — | — |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Verastem, Inc.'s CIK number?
Verastem, Inc.'s SEC CIK number is 0001526119 (1526119). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Verastem, Inc.'s SEC filings?
All of Verastem, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Verastem, Inc. last report earnings?
Verastem, Inc. (VSTM) most recently filed an earnings 8-K with the SEC on Feb 4, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001104659-26-010036). This is Verastem, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Verastem, Inc.'s most recent earnings 8-K?
Verastem, Inc.'s latest earnings 8-K (Item 2.02) was filed Feb 4, 2026 under accession 0001104659-26-010036. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Verastem, Inc.'s latest earnings 8-K →
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